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Type 2 diabetes and obesity among sub-Saharan African native and migrant populations: dissection of environment and endogenous predisposition

Objective

Migration from Sub-Saharan Africa (SSA) to Europe is increasing. The limited evidence suggests that the risk of type 2 diabetes (T2D) and obesity among SSA migrants is higher than among their SSA peers living in Africa and European host populations. The reasons for these observations are only poorly understood, but may involve migration-related changes in lifestyle, genetic predisposition as well as pe¬culiarities in perceptions and practises. Contrasting the increasing number of African migrants in Europe, the health status and needs of these populations remain largely unexamined, and have only insufficiently been integrated into national plans, policies and strategies. Implementation of tailored intervention programmes among migrants implic¬itly requires the identification and the disentanglement of environmental, lifestyle and genetic factors modifying T2D and obesity risk.

The RODAM project addresses these fundamental health issues among a homogeneous, and one of the largest SSA migrant groups in Europe (i.e. Ghanaians). RODAM thus aims to contribute to the understanding of the complex interplay between environment, lifestyle, (epi)genetic as well as social factors in T2D and obesity among SSA immigrants, and to identify specific risk factors to guide intervention and prevention and to provide a basis for improving diagnosis and treatment.

In a multi-centre study, 6,250 Ghanaians aged >25 years will be re¬cruited in rural and urban Ghana, Germany, the Netherlands, and the UK. The differences in prevalence rates within Ghana on the one hand, and three European countries on the other, will allow us to unravel environmental, lifestyle and (epi)genetic as well as social factors in relation to T2D and obesity.

The proposed study will generate relevant results that will ultimately guide intervention programmes and will provide a basis for improving diagnosis and treatment among SSA migrants in Europe as well as in their counterparts in Africa and beyond.

Field of science

  • /medical and health sciences/clinical medicine/endocrinology/diabetes
  • /social sciences/sociology/demography/human migration

Call for proposal

FP7-HEALTH-2011-two-stage
See other projects for this call

Funding Scheme

CP-FP-SICA - Small/medium-scale focused research project for specific cooperation actions dedicated to international cooperation partner countries(SICA)

Coordinator

ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Address
Meibergdreef 15
1105AZ Amsterdam
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 796 318,45
Administrative Contact
Frank J.M. Groen (Mr.)

Participants (8)

KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY KUMASI
Ghana
EU contribution
€ 280 480
Address
Private Mail Bag, University Post Office
ASH Kumasi
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ellis Owusu-Dabo (Dr.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 675 680
Address
Chariteplatz 1
10117 Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eveline Fraessdorf (Ms.)
LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER
United Kingdom
EU contribution
€ 438 560
Address
Keppel Street
WC1E 7HT London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Greg Dow (Mr.)
DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG POTSDAM REHBRUECKE
Germany
EU contribution
€ 168 040
Address
Arthur-scheunert-allee 114-116
14558 Nuthetal
Activity type
Research Organisations
Administrative Contact
Judith Schaefer (Dr.)
UNIVERSITY OF GHANA
Ghana
EU contribution
€ 160 200
Address
.
N/A Legon Accra
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mary Twum-Barima (Ms.)
IMAGENES GMBH

Participation ended

Germany
Address
Robert Roessle Strasse 10
13125 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Martin Stock (Mr.)
FEDERATION INTERNATIONALE DU DIABETE

Participation ended

Belgium
EU contribution
€ 18 361,55
Address
Chaussee De La Hulpe 166
1170 Bruxelles
Activity type
Other
Administrative Contact
Silver Bahendeka (Dr.)
Source Bioscience plc
United Kingdom
EU contribution
€ 454 560
Address
Orchard Place, Business Park 1
NG8 6PX Nottingham
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Nick Cox (Mr.)