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Type 2 diabetes and obesity among sub-Saharan African native and migrant populations: dissection of environment and endogenous predisposition

Objectif

Migration from Sub-Saharan Africa (SSA) to Europe is increasing. The limited evidence suggests that the risk of type 2 diabetes (T2D) and obesity among SSA migrants is higher than among their SSA peers living in Africa and European host populations. The reasons for these observations are only poorly understood, but may involve migration-related changes in lifestyle, genetic predisposition as well as pe¬culiarities in perceptions and practises. Contrasting the increasing number of African migrants in Europe, the health status and needs of these populations remain largely unexamined, and have only insufficiently been integrated into national plans, policies and strategies. Implementation of tailored intervention programmes among migrants implic¬itly requires the identification and the disentanglement of environmental, lifestyle and genetic factors modifying T2D and obesity risk.

The RODAM project addresses these fundamental health issues among a homogeneous, and one of the largest SSA migrant groups in Europe (i.e. Ghanaians). RODAM thus aims to contribute to the understanding of the complex interplay between environment, lifestyle, (epi)genetic as well as social factors in T2D and obesity among SSA immigrants, and to identify specific risk factors to guide intervention and prevention and to provide a basis for improving diagnosis and treatment.

In a multi-centre study, 6,250 Ghanaians aged >25 years will be re¬cruited in rural and urban Ghana, Germany, the Netherlands, and the UK. The differences in prevalence rates within Ghana on the one hand, and three European countries on the other, will allow us to unravel environmental, lifestyle and (epi)genetic as well as social factors in relation to T2D and obesity.

The proposed study will generate relevant results that will ultimately guide intervention programmes and will provide a basis for improving diagnosis and treatment among SSA migrants in Europe as well as in their counterparts in Africa and beyond.

Appel à propositions

FP7-HEALTH-2011-two-stage
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Coordinateur

ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Adresse
Meibergdreef 15
1105AZ Amsterdam
Pays-Bas

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Frank J.M. Groen (Mr.)
Contribution de l’UE
€ 796 318,45

Participants (8)

KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY KUMASI
Ghana
Contribution de l’UE
€ 280 480
Adresse
Private Mail Bag, University Post Office
ASH Kumasi

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Ellis Owusu-Dabo (Dr.)
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Allemagne
Contribution de l’UE
€ 675 680
Adresse
Chariteplatz 1
10117 Berlin

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Eveline Fraessdorf (Ms.)
LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER
United Kingdom
Contribution de l’UE
€ 438 560
Adresse
Keppel Street
WC1E 7HT London

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Greg Dow (Mr.)
DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG POTSDAM REHBRUECKE
Allemagne
Contribution de l’UE
€ 168 040
Adresse
Arthur-scheunert-allee 114-116
14558 Nuthetal

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Type d’activité
Research Organisations
Contact administratif
Judith Schaefer (Dr.)
UNIVERSITY OF GHANA
Ghana
Contribution de l’UE
€ 160 200
Adresse
.
N/A Legon Accra

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Mary Twum-Barima (Ms.)
IMAGENES GMBH

Participation terminée

Allemagne
Adresse
Robert Roessle Strasse 10
13125 Berlin

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Martin Stock (Mr.)
FEDERATION INTERNATIONALE DU DIABETE

Participation terminée

Belgique
Contribution de l’UE
€ 18 361,55
Adresse
Chaussee De La Hulpe 166
1170 Bruxelles

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Type d’activité
Other
Contact administratif
Silver Bahendeka (Dr.)
Source Bioscience plc
United Kingdom
Contribution de l’UE
€ 454 560
Adresse
Orchard Place, Business Park 1
NG8 6PX Nottingham

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Nick Cox (Mr.)