Objective The essence of this proposal is to establish a collaborative training network which will develop novel immune-regulatory molecules from Bifidobacterium infantis 35624, for treatment of inflammatory diseases. A multidisciplinary team of four prestigious European partners has been assembled (SME & Coordinator - Alimentary Health Ltd (expert in developing probiotic products); Swiss Institute for Asthma and Allergy Research, (expert in immune-regulation); Vienna Institute of Biotechnology at Universität für Bodenkultur (expert in glycobiology); and University College Cork, Alimentary Pharmabiotics Centre and Department of Microbiology (expert in bioinformatics and glycobiology assembly in probiotic bacteria). Each partner will provide unique critical expertise, through knowledge, personnel and facilities which will be complementary and additive and will provide the synergistic expertise required to successfully deliver on the goal of this project and forge a long-lasting relationship. The end result: a unique opportunity for cross-sector state-of-the-art knowledge transfer and dissemination, through the identification of molecules from B. infantis 35624 with proven efficacy in the treatment of IBS and other inflammatory conditions – expected to have major commercialization, economic and health implications.B. infantis 35624 is a commensal micro-organism, originally isolated from human gastrointestinal tissue, which has demonstrated unique properties in human clinical studies. B. infantis 35624 consumption is associated with significant improvement in the composite score for abdominal pain/discomfort, bloating/distention, and/or bowel movement difficulty compared with placebo in two appropriately designed studies. No other bacterial strain has shown significant improvement in Irritable Bowel Syndrome (IBS) symptoms. The exact mechanisms underpinning the clinical benefit are not known but modulation of the host immune response is strongly believed to play a role. Fields of science medical and health sciencesclinical medicinepneumologyasthmanatural sciencesbiological sciencesmicrobiologybacteriologymedical and health scienceshealth sciencesinflammatory diseasesmedical and health sciencesbasic medicineimmunologymedical and health sciencesclinical medicineallergology Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2011-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Call for proposal FP7-PEOPLE-2011-IAPP See other projects for this call Funding Scheme MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Coordinator SCHWEIZERISCHES FORSCHUNGSINSTITUT FUER HOCHGEBIRGSKLIMA UND MEDIZIN IN DAVOS Address Promenade 35 7270 Davos platz Switzerland See on map Region Schweiz/Suisse/Svizzera Ostschweiz Graubünden / Grigioni / Grischun Activity type Research Organisations Administrative Contact Liam O'mahony (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all ALIMENTARY HEALTH LTD Ireland EU contribution € 317 791,00 Address Kinsale road building 2800 cork airport business park N/A Cork See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jennifer Roper (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Ireland EU contribution € 121 059,00 Address Western road T12 YN60 Cork See on map Region Ireland Southern South-East Activity type Higher or Secondary Education Establishments Administrative Contact David O'connell (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UNIVERSITAET FUER BODENKULTUR WIEN Austria EU contribution € 207 192,00 Address Gregor mendel strasse 33 1180 Wien See on map Region Ostösterreich Wien Wien Activity type Higher or Secondary Education Establishments Administrative Contact Friedrich Altmann (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data ALIMENTARY HEALTH PHARMA DAVOS AG Switzerland EU contribution € 141 863,00 Address Obere strasse 22 7270 Davos platz See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jennifer Roper (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data
