Skip to main content

Design of Novel Portable-Sensors Based on Suspension Arrays Composed of Monoclonal Antibody and
Bacteriophage Carrying Magnetically Loaded Nanoparticles and Surface Enhanced Raman Spectroscopy

Objective

In this project, we aim to develop nanotechnology-based systems for detection of pathogenic bacteria in several aqueous media mainly in environmental water based on suspension arrays together with a portable custom-designed detection system. The six objectives (six work packages) are as follows: (i) Nanostructured sensors surfaces, in which electron-beam, photo-, soft and dip-pen lithographies will be applied in the fabrication of functionalized low-cost (disposable) SERS substrates, specially designed for simultaneus Raman and Fluorescence enhancement; (ii) nanosorbents and their mixtures as suspension arrays against the target bacteria for capturing units in which firstly magnetically loaded nanoparticles will be produced and labelled/barcoaded with fluorosence dies and/or quantum dots and then bacteriophages, monoclonal antibodies, and/or aptamers will be immobilized onto these nanoparticles as bioligands to recognize and capture the target bacteria specifically; their mixtures will form the suspension arrays; (iii) target bacteria and bacteriophages; the target bacteria (as water pollutants), are Escherichia coli, Enterococcus species and Bacteroides ovatus; bacteriophages which will recognize these bacteria will be selected/produced as bioligands; (iv) aptamers; they will be selected/modified/produced; (v) sensors/array systems; a portable “Raman Spectrometer/Fluorescence Detector System” will be designed/produced that will be used together with the nanostructured sensors platforms, and finally (vi) validation; the materials and systems developed will be validated. This is a multidisciplinary and technological project and therefore brings together experts from different disciplines both from academia and industry. Basicly, the knowledge that will be developed/ accumulated at lab scale during the project will be transfered to the industrial partners for prototype productions, and then these will bring back to the academical institutions for validation tests.

Field of science

  • /natural sciences/biological sciences/microbiology/bacteriology
  • /engineering and technology/electrical engineering, electronic engineering, information engineering/electronic engineering/sensors

Call for proposal

FP7-PEOPLE-2011-IAPP
See other projects for this call

Funding Scheme

MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP)

Coordinator

HACETTEPE UNIVERSITESI
Address
Hacettepe Universitesi Beytepe Kampusu Rektorluk Binasi
06800 Cankaya Ankara
Turkey
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 243 328,80
Administrative Contact
Erhan Biskin (Prof.)

Participants (6)

BIYOMEDTEK BIYOMEDIKAL TEKNOLOJILERDERNEGI IKTISADI ISLETMESI
Turkey
EU contribution
€ 227 757,20
Address
Beysukent Mahallesi Dumluka
06800 Cankaya Ankara
Activity type
Other
Administrative Contact
Sinan Egri (Mr.)
UNIVERSITY OF BRIGHTON
United Kingdom
EU contribution
€ 314 998,20
Address
Lewes Road Mithras House
BN2 4AT Brighton
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Jonathan Caplin (Dr.)
BILKENT UNIVERSITESI VAKIF
Turkey
EU contribution
€ 201 262,60
Address
Eskisehir Yolu 8 Km
06800 Bilkent Ankara
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Abdullah Atalar (Prof.)
APTARES AG

Participation ended

Germany
EU contribution
€ 235 096,40
Address
Am Scheunenviertel 1
15749 Mittenwalde
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Claudia Dahmen (Ms.)
GATE Elektronik Sanayi Ve Ticaret A.S
Turkey
EU contribution
€ 203 956,50
Address
Istanbul Yolu Ayas Kav. 16. Km 1-A
06370 Ankara
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Altug Kulengİr (Mr.)
ELIAVA BIO PREPARATIONS LTD
Georgia
EU contribution
€ 199 323,30
Address
Gotua Street 3
0160 Tbilisi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Nina Chanishvili (Mrs.)