Objective "The main objective of the EXGENOMES project is to develop new and improved thermostable enzymes for use, as reagents, in large-scale DNA synthesis and/or that can act on unnatural components such as in LNA (Locked Nucleic Acids). The target source for the new enzymes is a range of self-replicating mobile genetic elements (phages, plasmids and transposons) from thermophilic bacteria. Increased understanding of self-replication in many mobile genetic elements, such as phi29, has now made the commercial development of new self-priming & strand-displacing polymerases and other enzymes, much more plausible. A number of candidate enzymes, such as a new transposon-coded Thermus DNA polymerase are at hand for this project in the thermophilic bacteria & phage genome bank at Matis.Nucleic acids based technologies now underpin a large and fast-growing industry, including research, diagnostics and pharmaceutical production. Thermophilic enzymes have played a key role in this development, as polymerases (DNA and RNA), ligases, nucleases, reverse transcriptases, polynucleotide kinases, lysozymes and more, are of great importance in the research industry today. The partner SME´s are all active players in this area from bioprospecting (Prokazyme), laboratory distribution (A&A Biotechnologies), LNA manufacture & diagnostics (Exiqon) to DNA vaccine production (Touchlight Genetics).Together with the highly competent RTD partners the consortium is well positioned to implement the project according to its goals. The successful development of new thermostable polymerases and other enzymes with the desired properties would have a substantial impact on strengthening the current market status of the SME partners, resulting in growth in income and employment." Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acidsnatural sciencesbiological sciencesmicrobiologybacteriologynatural sciencesbiological sciencesmicrobiologyvirologynatural sciencesbiological sciencesgeneticsDNAnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Programme(s) FP7-SME - Specific Programme "Capacities": Research for the benefit of SMEs Topic(s) SME-2011-1 - Research for SMEs Call for proposal FP7-SME-2011 See other projects for this call Funding Scheme BSG-SME - Research for SMEs Coordinator PROKAZYME EHF Address Vinlandsleio 14 113 Reykjavik Iceland See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Jakob Kristjansson (Dr.) Links Contact the organisation Opens in new window EU contribution € 332 749,00 Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all A&A BIOTECHNOLOGY SC Poland EU contribution € 285 840,00 Address Ul strzelca 40 80-299 Gdansk See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Slawomir Dabrowski (Dr.) Links Contact the organisation Opens in new window Website Opens in new window TOUCHLIGHT GENETICS LIMITED GB EU contribution € 154 177,00 Address Queen anne street 40 W1G 9EL London See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Neil Porter (Dr.) Links Contact the organisation Opens in new window Website Opens in new window EXIQON AS Denmark EU contribution € 143 834,00 Address Bygstubben 9 2950 Vedbaek See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) projects.administrative_contact Peter Mouritzen (Dr.) Links Contact the organisation Opens in new window Website Opens in new window MATIS OHF Iceland EU contribution € 0,00 Address Vinlandsleid 12 113 Reykjavik See on map Activity type Research Organisations projects.administrative_contact Gudmunur Hreggvidsson (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIWERSYTET GDANSKI Poland EU contribution € 0,00 Address Ul. bazynskiego 8 80309 Gdansk See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Tadeusz Kaczorowski (Prof.) Links Contact the organisation Opens in new window Website Opens in new window MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ W WARSZAWIE Poland EU contribution € 0,00 Address Ul. ksiecia trojdena 4 02109 Warsaw See on map Activity type Research Organisations projects.administrative_contact Janusz Bujnicki (Prof.) Links Contact the organisation Opens in new window Website Opens in new window IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE GB EU contribution € 0,00 Address South kensington campus exhibition road SW7 2AZ London See on map Activity type Higher or Secondary Education Establishments projects.administrative_contact Tatjana Palalic (Ms.) Links Contact the organisation Opens in new window Website Opens in new window
