Objetivo The goal of this project is to develop new types of biosensors based on two different approaches: (i) a new bioanalytic microsystem platform for cell growth, manipulation and analysis using on-chip integrated microtubes and (ii) the use of synthetic self-propelled nanomotors for bioanalytical and biosensing applications. Based on the novel “Lab-in-a-tube” concept, we will design a multifunctional device for the capturing, growth and sensing of single cell behaviours inside “glass” microtubes to be employed for diverse biological applications. We will decorate the walls of the microtubes with proteins from the extracellular matrix enabling the long-term study of cellular changes such as mitosis time, spindle reorientation, DNA damage and cellular differentiation. These microtubes are fabricated by the well-established rolled-up nanotechnology developed in the host institution. Moreover, the multifunctionality of the “Lab-in-a-tube” platform will be extended by integrating different modules into a single microtubular unit, bringing up several applications such as optofluidics(bio)sensors, electrodes for electrochemical control and sensing, and magnetic biodetection.At the IIN institute in IFW Dresden, we are pioneers on the fabrication of catalytic microjet engines (microbots) and their use for transporting different kinds of objects in vitro into a fluid. The remote controlled motion of these autonomous microbots and the transport of microobjects and cells to specific targets within lab-on-a-chip systems is possible. Their walls can be biofunctionalized with enzymes, antibodies or DNA, the catalytic microbots representing a novel and unique tool for biosensing, environmental and biomedical applications. Our next step is to use biocompatible fuels to propel these microbots with the final aim of transporting and delivering drugs in vivo.The separation of cancer cells, bacteria and other biomaterials to build up new tissues or to replace disease cells are also aimed. Ámbito científico engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsengineering and technologyenvironmental biotechnologybiosensingnatural sciencesbiological sciencesgeneticsDNAengineering and technologyother engineering and technologiesmicrotechnologylab on a chipengineering and technologynanotechnology Programa(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) ERC-SG-LS9 - ERC Starting Grant - Applied life sciences and biotechnology Convocatoria de propuestas ERC-2012-StG_20111109 Consulte otros proyectos de esta convocatoria Régimen de financiación ERC-SG - ERC Starting Grant Institución de acogida FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA Aportación de la UE € 1 006 537,79 Dirección CARRER BALDIRI REIXAC PLANTA 2A 10-12 08028 Barcelona España Ver en el mapa Región Este Cataluña Barcelona Tipo de actividad Research Organisations Investigador principal Samuel Sánchez Ordóñez (Dr.) Contacto administrativo Josep Samitier Martí (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Beneficiarios (3) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA España Aportación de la UE € 1 006 537,79 Dirección CARRER BALDIRI REIXAC PLANTA 2A 10-12 08028 Barcelona Ver en el mapa Región Este Cataluña Barcelona Tipo de actividad Research Organisations Investigador principal Samuel Sánchez Ordóñez (Dr.) Contacto administrativo Josep Samitier Martí (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos LEIBNIZ INSTITUT FUR FESTKORPER UND WERKSTOFFORSCHUNG DRESDEN EV La participación finalizó Alemania Aportación de la UE € 95 772,46 Dirección HELMHOLTZSTRASSE 20 01069 Dresden Ver en el mapa Región Sachsen Dresden Dresden, Kreisfreie Stadt Tipo de actividad Research Organisations Contacto administrativo Birgit Benz (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV La participación finalizó Alemania Aportación de la UE € 397 569,75 Dirección HOFGARTENSTRASSE 8 80539 Munchen Ver en el mapa Región Bayern Oberbayern München, Kreisfreie Stadt Tipo de actividad Research Organisations Contacto administrativo Richard Segar (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos