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Gaining Productivity, Cost Efficiency and Sustainability in the Downstreaming Processing of Bio Products by novel Integration and Intensification strategies

Objectif

The European Life science and chemical industries increasingly depend on effi-cient, sustainable, and cost-effective bioprocessing platforms to remain competi-tive. A critical assessment of current bottlenecks during (bio) manufacturing clearly indicates that the recovery and purification of biologicals in large scale in responsible for many inefficiencies.

INTENSO proposes an evaluation of the current situation of the downstream processing scenario with the aim of identifying inefficiencies and concomitantly introduce a debottlenecking overarching strategy. The later will be build up on the basis of a multidisciplinary approach, which considers opportunities to im-prove the process technology and underlying chemistry / biology and materials science at the same time. INTENSO will work alongside 4 technological axes, targeting promising and up-coming technologies and tailoring such technologies to the manufacturing of various classes of (bio) products. Intensification of individual unit operations and global process integration, as well as, dovetailing with fermentation / cell cultivation will be employed to the mentioned end.

INTENSO will target new classes of (bio) products like Monoclonal Antibodies (Mabs), pDNA (e.g. for genetic vaccination), Virus Like Particles (VLP) or nano-plexes. All the mentioned new products are part of most industrial R&D pipelines and offer an excellent opportunity to introduce innovative bioprocessing.

The results of the project are expected to contribute to the understanding of current industrial downstream processing practice, to the definition and alleviation of current inefficiencies, to the development and / or implementation of novel technologies, and to more efficient / sustainable and cost effective (bio) manufacturing. Various technologies will be studied utilizing a nano-to-process strategy so as to introduce integration / intensification during bioprocessing.

Appel à propositions

FP7-KBBE-2012-6-singlestage
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Coordinateur

JACOBS UNIVERSITY BREMEN GGMBH
Adresse
Campus Ring 1
28725 Bremen
Allemagne

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Ronald Kieschnick (Mr.)
Contribution de l’UE
€ 810 801,48

Participants (16)

SARTORIUS BIA SEPARATIONS, SEPARACIJSKE TEHNOLOGIJE, D.O.O.
Slovénie
Contribution de l’UE
€ 288 596
Adresse
Mirce 21
5270 Ajdovscina

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Nika Lendero Krajnc (Dr.)
UNIVERSIDAD NACIONAL DE QUILMES
Argentine
Contribution de l’UE
€ 218 014,40
Adresse
Roque Saenz Pena 352
B1876BXD Bernal

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Mariano Grasselli (Prof.)
CHIPRO GMBH
Allemagne
Contribution de l’UE
€ 317 017,20
Adresse
Anne-conway-strasse 1
28359 Bremen

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Sebastian Thiem (Dr.)
UNIVERSITAET FUER BODENKULTUR WIEN
Autriche
Contribution de l’UE
€ 402 380
Adresse
Gregor Mendel Strasse 33
1180 Wien

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Alois Jungbauer (Prof.)
ICOSAGEN AS
Estonie
Contribution de l’UE
€ 274 460
Adresse
Nooruse 9
50411 Tartu

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Mart Ustav (Prof.)
SOFIA UNIVERSITY ST KLIMENT OHRIDSKI
Bulgarie
Contribution de l’UE
€ 297 620
Adresse
Bul Tzar Osvoboditel 15
1504 Sofia

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Valentina Ganeva (Prof.)
PROXCYS
Pays-Bas
Contribution de l’UE
€ 294 780
Adresse
Kampweg 2
7812 BS Emmen

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Marcel Raedts (Mr.)
INSTITUTO SUPERIOR TECNICO
Portugal
Contribution de l’UE
€ 321 153
Adresse
Avenida Rovisco Pais 1
1049 001 Lisboa

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Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Raquel Aires-Barros (Prof.)
INFOCONSULT GESELLSCHAFT FUR INFORMATIONSTECHNIK MBH
Allemagne
Contribution de l’UE
€ 415 123
Adresse
Am Kapellenberg 2
28759 Bremen

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Peter Knackfuß (Dr.)
BIOMEDAL SL
Espagne
Contribution de l’UE
€ 291 400
Adresse
Avenida Americo Vespucio 5, Bloque 4, Planta 1a, Modulo 12, Parque Cientifico Y Tecnologico Cartuja 39
41092 Sevilla

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Cebolla Ramirez Angel (Mr.)
VIRTUALPIE LTD
United Kingdom
Contribution de l’UE
€ 392 418
Adresse
The Fluid Engineering Centre
MK43 0AJ Cranfield

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Mike Butcher (Mr.)
ERA BIOTECH

Participation terminée

Espagne
Contribution de l’UE
€ 123 460,45
Adresse
Calle Baldiri Reixac 15-21
08028 Barcelona
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Blanca Llompart (Dr.)
GENERI BIOTECH
Tchéquie
Contribution de l’UE
€ 300 600
Adresse
Machkova 587
50011 Hradec Kralove

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Martin Martin (Dr.)
ETHRIS GMBH
Allemagne
Contribution de l’UE
€ 295 028
Adresse
Semmelweisstr. 3
82152 Planegg

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Carsten Rudolph (Dr.)
DSM BIOLOGICS COMPANY BV

Participation terminée

Pays-Bas
Contribution de l’UE
€ 46 508,92
Adresse
Zuiderweg 72/2
9744 AP Groningen
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Rolf Douwenga (Mr.)
ZERA INTEIN PROTEIN SOLUTIONS SL
Espagne
Contribution de l’UE
€ 171 599,55
Adresse
Cavallers 50
Barcelona

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Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Miriam Bastida (Mrs.)