Obiettivo In the research part we will deal with the basic principles of the innate immune defense used to control tumors and viral infections with a focus on NK and NK/T cells, including analysis of NK receptor genomics/epigenetics, gene polymorphisms/disease linkage, differentiation of hitherto unrecognized NK cell subpopulations and novel ligands for NK receptors exposed by tumor and/or virally infected cells. We will investigate the mechanisms installed by tumors and viruses to avoid or subvert immune defenses. This will include the investigation of the role of NK/T cell subpopulations in the defense against tumors and infections by herpes virus family members, some being involved intumor formation, in the development of inflammatory diseases and/or constituting a frequent complication during tumor therapy. The project will support anti-tumor and anti-viral therapies by developing novel technology for NK cell generation from cord blood stem cells for NK cell infusions in patients, by genetic engineering of NK cells and by using NK receptors and their ligands to develop novel reagents for amplifying anti-tumor and -viral activities of NK/T cells. It will further undertake basic studies on the potential of the newly emerging iPS cell technology for reconstituting immune systems including NK cells in patients with hematologic cancers.All students of this ITN will be trained in state-of-the-art immunotechnology including wider aspects of molecular medicine at the individual partner universities. An exchange of students between the different partners will be organized to ensure that every participant will be trained in several laboratories/universities with different expertise. It will further include network-wide training modules with cutting-edge lectures of internationally recognized research experts in the field, state-of-the-art seminars in the front-line technologies used in this project as well as courses in genome-wide bioinformatics, business and patent rights. Campo scientifico medical and health scienceshealth sciencesinflammatory diseasesmedical and health sciencesmedical biotechnologygenetic engineeringmedical and health sciencesmedical biotechnologycells technologiesstem cellsmedical and health sciencesclinical medicineoncologymedical and health sciencesbasic medicineimmunologyimmunotherapy Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2012-ITN - Marie-Curie Action: "Initial Training Networks" Invito a presentare proposte FP7-PEOPLE-2012-ITN Vedi altri progetti per questo bando Meccanismo di finanziamento MC-ITN - Networks for Initial Training (ITN) Coordinatore MEDIZINISCHE HOCHSCHULE HANNOVER Contributo UE € 450 214,75 Indirizzo Carl-Neuberg-Strasse 1 30625 Hannover Germania Mostra sulla mappa Regione Niedersachsen Hannover Region Hannover Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Simone Hess (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (10) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto INSTITUT PASTEUR Francia Contributo UE € 515 197,32 Indirizzo RUE DU DOCTEUR ROUX 25-28 75724 Paris Mostra sulla mappa Regione Ile-de-France Ile-de-France Paris Tipo di attività Research Organisations Contatto amministrativo Marie-Laure Rosso (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE HEBREW UNIVERSITY OF JERUSALEM Israele Contributo UE € 224 613,84 Indirizzo EDMOND J SAFRA CAMPUS GIVAT RAM 91904 Jerusalem Mostra sulla mappa Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Jane Turner (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSIDAD POMPEU FABRA Spagna Contributo UE € 226 681,62 Indirizzo PLACA DE LA MERCE, 10-12 08002 Barcelona Mostra sulla mappa Regione Este Cataluña Barcelona Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Miguel López Botet (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Regno Unito Contributo UE € 285 056,64 Indirizzo TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge Mostra sulla mappa Regione East of England East Anglia Cambridgeshire CC Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Renata Schaeffer (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato KING'S COLLEGE LONDON Partecipazione conclusa Regno Unito Contributo UE Nessun dato Indirizzo STRAND WC2R 2LS London Mostra sulla mappa Regione London Inner London — West Westminster Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Paul Labbett (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato UNIVERSITY COLLEGE LONDON Contributo UE € 285 056,64 Indirizzo GOWER STREET WC1E 6BT LONDON Mostra sulla mappa Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Malgorzata Kielbasa (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato MEDIZINISCHE UNIVERSITAET WIEN Austria Contributo UE € 889 734,13 Indirizzo SPITALGASSE 23 1090 Wien Mostra sulla mappa Regione Ostösterreich Wien Wien Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Arndt Von Haeseler (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato MILTENYI BIOTEC GMBH Germania Contributo UE € 222 068,88 Indirizzo FRIEDRICH EBERT STRASSE 68 51429 Bergish Gladbach Mostra sulla mappa Regione Nordrhein-Westfalen Köln Rheinisch-Bergischer Kreis Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Sabrina Schmitz (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato GLYCOSTEM-THERAPEUTICS B.V. Paesi Bassi Contributo UE € 236 861,46 Indirizzo KLOOSTERSTRAAT 9 KAMER RE 1134 5349 AB Oss Mostra sulla mappa Regione Zuid-Nederland Noord-Brabant Noordoost-Noord-Brabant Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Wim Jongen (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato AFFIMED THERAPEUTICS AG Germania Contributo UE € 190 800,72 Indirizzo IN NEUENHEIMER FELD 582 69120 HEIDELBERG Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Michaela Braun (Mrs.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
