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Molecular technology for nuclear imaging and radionuclide therapy

Final Report Summary - TRACENTREAT (Molecular technology for nuclear imaging and radionuclide therapy)

The Trace ’n Treat Training network (Oct 2012 – Oct 2016) has fulfilled the very ambitious goal to train young researchers in the field of nuclear diagnostics and radionuclide therapy by bringing together disciplines that cover the entire health care cycle, from prevention to treatment. The research objectives of this project were: production of radionuclides with the most appropriate properties for molecular imaging and/or radionuclide therapy, their incorporation in newly designed molecular and supramolecular carriers and finally their pre-clinical evaluation and comparison. The fellows showed that multidisciplinary training and supportive network tremendously help to accomplish these goals, resulting in the in vivo evaluation of three type of carriers.

Important highlights
The most important highlights of the project are the two awards given to two female researchers. Alexandra Arranja received a prize for her PhD thesis ‘’Development of copolymer nano-carriers for imaging and therapy’’ from the “Association des Universités de I’Académie de Strasbourg”.
Oleksandra Ivashchenko was chosen by the Society of Nuclear Medicine and Molecular Imaging to be the recipient of the Alavi-Mandell Award for her publication entitled “Ultra-High-Sensitivity Submillimeter Mouse SPECT”. Furthermore, a paper in collaboration between MILabs, TU Delft and the CNRS became the cover of Biomaterials Science.

YouTube, Wiki and Publications
Other than doing multidisciplinary research, the fellows of Trace’nTreat also contributed to the education of the general public by organising outreach workshops, spreading YouTube videos and contributing to Wikipedia articles on topics related to the project.
A long list of scientific publications have appeared, most of which have at least three partners of the consortium, showing that multidisciplinary research is possible when given the support of the right network

Trace ‘n Treat consortium
The Trace’nTreat network was a cooperation between a number of leading European institutes and industrial partners: Erasmus MC, MILabs, Johannes Gutenberg Universität Mainz, Medizinische Hochschule Hannover, Ghent University, Centre National de la Recherche Scientifique – Institute Charles Sadron, IDB Holland, Urenco Nederland, Institute of Transuranium Elements and TU Delft.

The Radiation Science and Technology department of the Delft University of Technology, the Netherlands, was responsible for the coordination of the project.