Objective The ITN TIMCC brings together eight expert teams from different disciplines within Immunology, Genetics and Oncology, to provide substantive and methodological training in the analysis of the role of the Tumor Infiltrating Myeloid Cell Compartment (TIMCC) of the innate immune system. Leukocytes recruited to (pre)malignant tissues are mainly myeloid cells. They can either prevent or functionally contribute to cancer development. However, the mechanisms underlying pro- versus anti-tumor programming of neoplastic tissues by these immune cells remain obscure.The ITN TIMCC aims to improve anti-tumor therapy by defining general and tumor type specific molecular and cellular immunological pathways (e.g signal transduction and downstream effector pathways) in tumor development and during therapeutic intervention based on an extensive analysis of the infiltrating myeloid cell compartment in human tumor biopsies using a large variety of techniques and functional analysis of the corresponding models of a variety of human tumors, affecting different organs, in a unique cohort of genetically modified mice treated with different types of anti-tumor therapy.The program will train the appointed researchers in a variety of methodology and technology from genomic technologies and bioinformatics via genetically modified mice to the design and application of therapeutic strategies to understand and manipulate the many interactions of the myeloid cell compartment with developing tumors. By defining underlying molecular and cellular pathways new targets will be identified to be explored by the participating SMEs. The program will deliver young researchers equipped with a broad knowledge in immunology, genetics and oncology and insight in the complexity of translational medicine therefore better prepared to meet new challenges in the field. Fields of science natural sciencesbiological sciencesgeneticsmedical and health sciencesbasic medicineimmunologymedical and health sciencesclinical medicineoncologynatural sciencesmathematicspure mathematicsmathematical analysisfunctional analysis Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2012-ITN - Marie-Curie Action: "Initial Training Networks" Call for proposal FP7-PEOPLE-2012-ITN See other projects for this call Funding Scheme MC-ITN - Networks for Initial Training (ITN) Coordinator ACADEMISCH ZIEKENHUIS LEIDEN Address Albinusdreef 2 2333 ZA Leiden Netherlands See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Administrative Contact Ruud Esveld (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN Germany EU contribution € 447 437,76 Address Regina pacis weg 3 53113 Bonn See on map Region Nordrhein-Westfalen Köln Bonn, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Daniela Hasenpusch (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data QUEEN MARY UNIVERSITY OF LONDON United Kingdom EU contribution € 573 413,28 Address 327 mile end road E1 4NS London See on map Region London Inner London — East Tower Hamlets Activity type Higher or Secondary Education Establishments Administrative Contact Thorsten Hagemann (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data UPPSALA UNIVERSITET Sweden EU contribution € 523 150,32 Address Von kraemers alle 4 751 05 Uppsala See on map Region Östra Sverige Östra Mellansverige Uppsala län Activity type Higher or Secondary Education Establishments Administrative Contact Pirkko Boox (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS Netherlands EU contribution € 477 022,92 Address Plesmanlaan 121 1066 CX Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Activity type Research Organisations Administrative Contact Henri Van Luenen (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data TECHNISCHE UNIVERSITAET DRESDEN Germany EU contribution € 447 437,76 Address Helmholtzstrasse 10 01069 Dresden See on map Region Sachsen Dresden Dresden, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Beate Brenner (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data ALLIGATOR BIOSCIENCE AB Sweden EU contribution € 226 772,04 Address Scheelevagen 19a 22370 Lund See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Jennifer Glennon (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data SYNOVO GMBH Germany EU contribution € 190 800,72 Address Paul ehrlich str 15 72076 Tuebingen See on map Region Baden-Württemberg Tübingen Tübingen, Landkreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Michael Burnet (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data
