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Content archived on 2024-06-18

Beyond the Genome; training the next generation of ophthalmic researchers

Objective

Eye research has often blazed a trail for other disciplines to follow, giving a lead in neuroscience, genetics, the development of gene- and stem-cell therapies and other important areas of medical research. In recent years, geneticists have made many remarkable discoveries of relevance both to normal human vision and the development of inherited retinal pathology. However the genes and mutations identified account for only a proportion of cases of inherited retinal degeneration, and recent discoveries hint at new classes of mutations which are either largely undetected or the significance of which is missed by conventional genetics. In addition, for those genes implicated there often remains a black box between mutations and disease; how do defects in a given protein manifest symptoms in the eye and what underlies the huge variation in symptoms, severity and response to treatment? The objectives of EyeTN are twofold; to address these knowledge gaps through cutting edge research using novel techniques, including transcriptomics analyses, whole genome and single target RNAi, the development of animal and cell-based disease models, stem cell biology, bioinformatics and hands on experience of pharmaceutical research with direct translational targets; and to give the next generation of European ophthalmic researchers unparalleled opportunities to train with a consortium of the best inherited blindness research labs in the world. The Network spans academic, healthcare and commercial research sectors and is already well established with many existing collaborations. All fellows will carry out one or more components of their research and training in a commercial environment and attend a workshop on translating ideas and discoveries into commercially viable Bioscience produces and therapies, fostering an entrepreneurial mindset and ensuring that we train a pool of researchers who are able to communicate effectively with both academic and commercial bioscience colleagues.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-ITN
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-ITN - Networks for Initial Training (ITN)

Coordinator

UNIVERSITY OF LEEDS
EU contribution
€ 981 389,08
Address
WOODHOUSE LANE
LS2 9JT Leeds
United Kingdom

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Region
Yorkshire and the Humber West Yorkshire Leeds
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (6)

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