Development of an integrated platform for nanoparticle analysis to verify their possible toxicity and the eco-toxicity

Project Information

DIPNA

Grant agreement ID: 32131

Start date 1 November 2006

End date 31 October 2009

Funded under

• Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006.

Total cost € 4 535 199,00

EU contribution € 2 793 235,00

Coordinated by

CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE SCIENZE FISICHE DELLA MATERIA
Italy

Objective

The fast-pacing development of nanosciences and nanotechnologies is due to their great potential in improving the quality of life and in creating novel knowledge-based sustainable processes. This unprecedented "nano-pollution" may in fact pose risks to human (manufacturers and end-users) and animal health that we cannot evaluate at present because of the complete lack of appropriate instruments and bioassays. The DIPNA project aims at creating and validating these instruments and assays, and to propose to the EU and international communities new parameters for detection of nanopollution and evaluation of occupational nanotoxicology, in order to promote prevention and nanosafety in manufacturing and handling.

In this novel, multidisciplinary, multination al research project it will be developed a precise knowledge on nano-immunotoxicity, i.e. the impact of nanoparticles and nanopollution in general on human defence cells. This knowledge will be validated in comparison with nano-genotoxicity and nano-carcinogenicity, i.e. studying in parallel the activity of nanoparticles in a standardised transformation assay in vitro, to predict the potential pathological risks of exposure to nanoparticles for human health.

The project will be divided in 6 workpackages:
1. Production and physico-chemical characterisation of nanoparticles;
2. Evaluation of NP interaction with human defence cells: selection of representative cell systems;
3. Evaluation of one-to-one NP-cell interaction: definition of threshold and do se-dependent effects;
4. Evaluation of chronic and repeated exposure: eco-nanotoxicity;
5. Field validation and development platform;
6. Coordination, management, training, and public awareness.

The scientific knowledge gained during this project will provide the ground for a development platform, aiming at standardising and field-validating prototypic assays and related instruments for biodetection of nanoparticle-associated health risks.

Fields of science

• engineering and technology › electrical engineering, electronic engineering, information engineering › electronic engineering › control systems
• natural sciences › chemical sciences › inorganic chemistry › transition metals
• engineering and technology › electrical engineering, electronic engineering, information engineering › electronic engineering › sensors
• engineering and technology › nanotechnology › nano-materials
• natural sciences › physical sciences › optics › spectroscopy

Programme(s)

• FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006.

Topic(s)

• NMP-2004-3.4.5.1 - Basic materials and industrial process research on functional materials for fuel cells

Call for proposal

FP6-2004-NMP-TI-4
See other projects for this call

Funding Scheme

STREP - Specific Targeted Research Project

Coordinator

CONSORZIO NAZIONALE INTERUNIVERSITARIO PER LE SCIENZE FISICHE DELLA MATERIA

• EU contribution: No data
• Address: via della Vasca Navale, 84 ; ROMA ; Italy
• Total cost: No data

Participants (9)

"PARIS LODRON" UNIVERSITAT SALZBURG

Austria

• EU contribution: No data
• Address: Kapitelgasse 4-6 ; SALZBURG
• Total cost: No data

CONSIGLIO NAZIONALE DELLE RICERCHE

Italy

• EU contribution: No data
• Address: Piazzale Aldo Moro 7 ; ROMA
• Total cost: No data

GRIMM AEROSOL TECHNIK

Germany

• EU contribution: No data
• Address: Dorfstrasse 9 ; AINRING
• Total cost: No data

VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK NV

Belgium

• EU contribution: No data
• Address: Boeretang 200 ; MOL
• Total cost: No data

CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA RECHERCHE ET DEVELOPMENT

Switzerland

• EU contribution: No data
• Address: Jaquet-Droz 1 ; NEUCHÂTEL
• Total cost: No data

COMMISSION OF THE EUROPEAN COMMUNITIES - DIRECTORATE GENERAL -JOINT RESEARCH CENTRE

Belgium

• EU contribution: No data
• Address: 200 rue de la Loi ; BRUXELLES
• Total cost: No data

FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V

Germany

• EU contribution: No data
• Address: Hansastraße 27C ; MÜNCHEN
• Total cost: No data

FUNDACIÓ PRIVADA INSTITUT CATALA DE NANOTECNOLOGIA

Spain

• EU contribution: No data
• Address: Campus de la UAB Edifici C ; BELLATERRA
• Total cost: No data

UNIVERSITÀ DEGLI STUDI MAGNA GRAECIA DI CATANZARO

Italy

• EU contribution: No data
• Address: Campus Universitario Germaneto, Viale Europa-località Germaneto ; CATANZARO
• Total cost: No data