Objective
The fast-pacing development of nanosciences and nanotechnologies is due to their great potential in improving the quality of life and in creating novel knowledge-based sustainable processes. This unprecedented "nano-pollution" may in fact pose risks to human (manufacturers and end-users) and animal health that we cannot evaluate at present because of the complete lack of appropriate instruments and bioassays. The DIPNA project aims at creating and validating these instruments and assays, and to propose to the EU and international communities new parameters for detection of nanopollution and evaluation of occupational nanotoxicology, in order to promote prevention and nanosafety in manufacturing and handling.
In this novel, multidisciplinary, multination al research project it will be developed a precise knowledge on nano-immunotoxicity, i.e. the impact of nanoparticles and nanopollution in general on human defence cells. This knowledge will be validated in comparison with nano-genotoxicity and nano-carcinogenicity, i.e. studying in parallel the activity of nanoparticles in a standardised transformation assay in vitro, to predict the potential pathological risks of exposure to nanoparticles for human health.
The project will be divided in 6 workpackages:
1. Production and physico-chemical characterisation of nanoparticles;
2. Evaluation of NP interaction with human defence cells: selection of representative cell systems;
3. Evaluation of one-to-one NP-cell interaction: definition of threshold and do se-dependent effects;
4. Evaluation of chronic and repeated exposure: eco-nanotoxicity;
5. Field validation and development platform;
6. Coordination, management, training, and public awareness.
The scientific knowledge gained during this project will provide the ground for a development platform, aiming at standardising and field-validating prototypic assays and related instruments for biodetection of nanoparticle-associated health risks.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering control systems
- natural sciences chemical sciences inorganic chemistry transition metals
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- engineering and technology nanotechnology nano-materials
- natural sciences physical sciences optics spectroscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-NMP-TI-4
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
ROMA
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.