Objective
This project, entitled “Hybrid polymer-peptide hydrogels for Cell Therapy” (HYCELT) will produce cost-effective neuronal stem cell (NSC) scaffolds for central nervous system regeneration using a fibrous gel that has all the necessary requisites for fast clinical translation: cell-instructive, biocompatible, injectable and biodegradable. Finding a perfect methodology to heal spinal cord damage is a challenge of current times. Peptides are used for this purpose because they are biocompatible, biodegradable and will produce suitable gelatinous environments for cell growth at extremely low concentrations. The target of HYCELT is to demonstrate this technology in vitro, with follow-on work focussed on in vivo studies in appropriate animal models and in collaboration with clinical scientists to produce a global therapy that will change the lives of thousands of people suffering from irreparable spinal cord injury. HYCELT brings together a talented young fellow with a background in polymer hydrogels with an internationally blossoming group in polymer nanotechnology and well-established UK groups in peptide/materials science and biomaterials. HYCELTs multidisciplinary solution will exploit polymer-peptide hydrogel system also be applied in the vast field of drug delivery. Moreover as it will be developed in concert with Merck Serono (Italy), the biotechnology world-leaders in the field of therapeutics, it will be immediately applicable to living system. The supervisory team has been selected from experts at Aston, Sheffield and Merck (Rome) to provide a multidisciplinary training programme for the fellow and to ensure success of the ambitious research targets of HYCELT.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences neurobiology
- natural sciences biological sciences biochemistry biomolecules
- engineering and technology nanotechnology
- natural sciences chemical sciences polymer sciences
- medical and health sciences medical biotechnology cells technologies stem cells
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2012-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
B4 7ET Birmingham
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.