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eNanoMapper - A Database and Ontology Framework for Nanomaterials Design and Safety Assessment

Objective

eNanoMapper will develop a data management and analysis infrastructure together with ontologies supporting the safety assessment activities of the European Nanomaterials research and development community. The project will address the requirements of safety assessment of nanomaterials by providing databases, analysis tools and ontologies for risk assessment and linking them with existing resources in this area.

The project plan involves close cooperation with NanoSafety Cluster members and other international organisations such as OECD, ISO/CEN, EC JRC, and EChA. Their requirements will guide the development of tools for experimental design, model building, and meta analysis across multiple datasets.

An ontology for nanomaterials will be developed to provide the following features: annotation of nanostructures and relevant biological properties, annotation of experimental model systems (e.g. cell lines), conditions, and protocols, complex search and reasoning capabilities, and the integration of data from existing nanotoxicology sources.

Systematic physicochemical, geometrical, structural, and biological studies of nanomaterials are nearly absent in the public domain. The establishment of a universal standardisation schema and infrastructure for nanomaterials safety assessment is a key project goal. It should catalyze collaboration, integrated analysis, and discoveries from data organised within a knowledge-based framework. It will support the discovery of nanomaterial properties responsible for toxicity, the identification of toxicity pathways and nano-bio interactions from linked datasets, ontologies, omics data and external data sources.

By interfacing with statistical and data mining tools we will be able to provide scientifically sound guidelines for experimental design as well as computational models for predicting nanotoxicity. These computational models will help to design safe nanomaterials and improve the risk assessment of existing nanoparticles.

Field of science

  • /natural sciences/computer and information sciences/databases
  • /humanities/philosophy, ethics and religion/philosophy/metaphysics/ontology
  • /engineering and technology/nanotechnology/nano-materials
  • /natural sciences/computer and information sciences/data science/data mining

Call for proposal

FP7-NMP-2013-SMALL-7
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

EDELWEISS CONNECT GMBH
Address
Hochbergerstrasse 60C
4057 Basel
Switzerland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 876 225,60
Administrative Contact
Barry Hardy (Dr.)

Participants (9)

TEKNOLOGIAN TUTKIMUSKESKUS VTT

Participation ended

Finland
Address
Tekniikantie 4 A
02044 VTT Espoo
Activity type
Research Organisations
Administrative Contact
Roland Grafström (Prof.)
NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA
Greece
EU contribution
€ 355 960
Address
Heroon Polytechniou 9 Zographou Campus
15780 Athina
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Georgia Mertzelou (Ms.)
IN SILICO TOXICOLOGY GMBH
Switzerland
EU contribution
€ 519 980
Address
Altkircherstrasse 4
4054 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Christoph Helma (Dr.)
IDEACONSULT LIMITED LIABILITY COMPANY
Bulgaria
EU contribution
€ 373 840
Address
Angel Kanchev 4
1000 Sofia
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Luben Boyanov (Dr.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 257 700
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Per-Olof Larsson (Mr.)
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY

Participation ended

Finland
EU contribution
€ 36 018,42
Address
Tekniikantie 21
02150 Espoo
Activity type
Research Organisations
Administrative Contact
Roland Grafström (Prof.)
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany
EU contribution
€ 372 080
Address
Meyerhofstrasse 1
69117 Heidelberg
Activity type
Research Organisations
Administrative Contact
Phil Irving (Dr.)
UNIVERSITEIT MAASTRICHT
Netherlands
EU contribution
€ 843 334,40
Address
Minderbroedersberg 4-6
6200 MD Maastricht
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Joseph Ih Janssen (Dr.)
MISVIK BIOLOGY OY
Finland
EU contribution
€ 361 731,58
Address
Karjakatu 35 B
20520 Turku
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Vesa Hongisto (Dr.)