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eNanoMapper - A Database and Ontology Framework for Nanomaterials Design and Safety Assessment

Objetivo

eNanoMapper will develop a data management and analysis infrastructure together with ontologies supporting the safety assessment activities of the European Nanomaterials research and development community. The project will address the requirements of safety assessment of nanomaterials by providing databases, analysis tools and ontologies for risk assessment and linking them with existing resources in this area.

The project plan involves close cooperation with NanoSafety Cluster members and other international organisations such as OECD, ISO/CEN, EC JRC, and EChA. Their requirements will guide the development of tools for experimental design, model building, and meta analysis across multiple datasets.

An ontology for nanomaterials will be developed to provide the following features: annotation of nanostructures and relevant biological properties, annotation of experimental model systems (e.g. cell lines), conditions, and protocols, complex search and reasoning capabilities, and the integration of data from existing nanotoxicology sources.

Systematic physicochemical, geometrical, structural, and biological studies of nanomaterials are nearly absent in the public domain. The establishment of a universal standardisation schema and infrastructure for nanomaterials safety assessment is a key project goal. It should catalyze collaboration, integrated analysis, and discoveries from data organised within a knowledge-based framework. It will support the discovery of nanomaterial properties responsible for toxicity, the identification of toxicity pathways and nano-bio interactions from linked datasets, ontologies, omics data and external data sources.

By interfacing with statistical and data mining tools we will be able to provide scientifically sound guidelines for experimental design as well as computational models for predicting nanotoxicity. These computational models will help to design safe nanomaterials and improve the risk assessment of existing nanoparticles.

Ámbito científico

  • /ciencias naturales/informática y ciencias de la información/base de datos
  • /ingeniería y tecnología/nanotecnología/nanomateriales
  • /ciencias naturales/informática y ciencias de la información/ciencia de datos/extracción de datos

Convocatoria de propuestas

FP7-NMP-2013-SMALL-7
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Régimen de financiación

CP-FP - Small or medium-scale focused research project

Coordinador

EDELWEISS CONNECT GMBH
Dirección
Hochbergerstrasse 60C
4057 Basel
Suiza
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Aportación de la UE
€ 876 225,60
Contacto administrativo
Barry Hardy (Dr.)

Participantes (9)

TEKNOLOGIAN TUTKIMUSKESKUS VTT

La participación finalizó

Finlandia
Dirección
Tekniikantie 4 A
02044 VTT Espoo
Tipo de actividad
Research Organisations
Contacto administrativo
Roland Grafström (Prof.)
NATIONAL TECHNICAL UNIVERSITY OF ATHENS - NTUA
Greece
Aportación de la UE
€ 355 960
Dirección
Heroon Polytechniou 9 Zographou Campus
15780 Athina
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Georgia Mertzelou (Ms.)
IN SILICO TOXICOLOGY GMBH
Suiza
Aportación de la UE
€ 519 980
Dirección
Altkircherstrasse 4
4054 Basel
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Christoph Helma (Dr.)
IDEACONSULT LIMITED LIABILITY COMPANY
Bulgaria
Aportación de la UE
€ 373 840
Dirección
Angel Kanchev 4
1000 Sofia
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Luben Boyanov (Dr.)
KAROLINSKA INSTITUTET
Suecia
Aportación de la UE
€ 257 700
Dirección
Nobels Vag 5
17177 Stockholm
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Per-Olof Larsson (Mr.)
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY

La participación finalizó

Finlandia
Aportación de la UE
€ 36 018,42
Dirección
Tekniikantie 21
02150 Espoo
Tipo de actividad
Research Organisations
Contacto administrativo
Roland Grafström (Prof.)
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Alemania
Aportación de la UE
€ 372 080
Dirección
Meyerhofstrasse 1
69117 Heidelberg
Tipo de actividad
Research Organisations
Contacto administrativo
Phil Irving (Dr.)
UNIVERSITEIT MAASTRICHT
Países Bajos
Aportación de la UE
€ 843 334,40
Dirección
Minderbroedersberg 4-6
6200 MD Maastricht
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Joseph Ih Janssen (Dr.)
MISVIK BIOLOGY OY
Finlandia
Aportación de la UE
€ 361 731,58
Dirección
Karjakatu 35 B
20520 Turku
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contacto administrativo
Vesa Hongisto (Dr.)