Ziel
eNanoMapper will develop a data management and analysis infrastructure together with ontologies supporting the safety assessment activities of the European Nanomaterials research and development community. The project will address the requirements of safety assessment of nanomaterials by providing databases, analysis tools and ontologies for risk assessment and linking them with existing resources in this area.
The project plan involves close cooperation with NanoSafety Cluster members and other international organisations such as OECD, ISO/CEN, EC JRC, and EChA. Their requirements will guide the development of tools for experimental design, model building, and meta analysis across multiple datasets.
An ontology for nanomaterials will be developed to provide the following features: annotation of nanostructures and relevant biological properties, annotation of experimental model systems (e.g. cell lines), conditions, and protocols, complex search and reasoning capabilities, and the integration of data from existing nanotoxicology sources.
Systematic physicochemical, geometrical, structural, and biological studies of nanomaterials are nearly absent in the public domain. The establishment of a universal standardisation schema and infrastructure for nanomaterials safety assessment is a key project goal. It should catalyze collaboration, integrated analysis, and discoveries from data organised within a knowledge-based framework. It will support the discovery of nanomaterial properties responsible for toxicity, the identification of toxicity pathways and nano-bio interactions from linked datasets, ontologies, omics data and external data sources.
By interfacing with statistical and data mining tools we will be able to provide scientifically sound guidelines for experimental design as well as computational models for predicting nanotoxicity. These computational models will help to design safe nanomaterials and improve the risk assessment of existing nanoparticles.
Wissenschaftliches Gebiet
- NaturwissenschaftenInformatik und InformationswissenschaftenWissensverarbeitungOntologie
- NaturwissenschaftenInformatik und InformationswissenschaftenDatenbank
- NaturwissenschaftenInformatik und InformationswissenschaftenDatenwissenschaftenData Mining
- Technik und TechnologieNanotechnologieNanomaterialien
Programm/Programme
Thema/Themen
Aufforderung zur Vorschlagseinreichung
FP7-NMP-2013-SMALL-7
Andere Projekte für diesen Aufruf anzeigen
Finanzierungsplan
CP-FP - Small or medium-scale focused research project
Koordinator
4057 Basel
Schweiz
Auf der Karte ansehen
Beteiligte (9)
Beteiligung beendet
02044 VTT Espoo
157 80 Athina
Auf der Karte ansehen
4054 Basel
Auf der Karte ansehen
1000 Sofia
Auf der Karte ansehen
17177 Stockholm
Auf der Karte ansehen
Beteiligung beendet
02150 Espoo
69117 Heidelberg
Auf der Karte ansehen
6200 MD Maastricht
Auf der Karte ansehen
20520 Turku
Auf der Karte ansehen