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eNanoMapper - A Database and Ontology Framework for Nanomaterials Design and Safety Assessment

Ziel

eNanoMapper will develop a data management and analysis infrastructure together with ontologies supporting the safety assessment activities of the European Nanomaterials research and development community. The project will address the requirements of safety assessment of nanomaterials by providing databases, analysis tools and ontologies for risk assessment and linking them with existing resources in this area.

The project plan involves close cooperation with NanoSafety Cluster members and other international organisations such as OECD, ISO/CEN, EC JRC, and EChA. Their requirements will guide the development of tools for experimental design, model building, and meta analysis across multiple datasets.

An ontology for nanomaterials will be developed to provide the following features: annotation of nanostructures and relevant biological properties, annotation of experimental model systems (e.g. cell lines), conditions, and protocols, complex search and reasoning capabilities, and the integration of data from existing nanotoxicology sources.

Systematic physicochemical, geometrical, structural, and biological studies of nanomaterials are nearly absent in the public domain. The establishment of a universal standardisation schema and infrastructure for nanomaterials safety assessment is a key project goal. It should catalyze collaboration, integrated analysis, and discoveries from data organised within a knowledge-based framework. It will support the discovery of nanomaterial properties responsible for toxicity, the identification of toxicity pathways and nano-bio interactions from linked datasets, ontologies, omics data and external data sources.

By interfacing with statistical and data mining tools we will be able to provide scientifically sound guidelines for experimental design as well as computational models for predicting nanotoxicity. These computational models will help to design safe nanomaterials and improve the risk assessment of existing nanoparticles.

Aufforderung zur Vorschlagseinreichung

FP7-NMP-2013-SMALL-7
Andere Projekte für diesen Aufruf anzeigen

Koordinator

EDELWEISS CONNECT GMBH
Adresse
Hochbergerstrasse 60c
4057 Basel
Schweiz

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Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Barry Hardy (Dr.)
EU-Beitrag
€ 876 225,60

Beteiligte (9)

TEKNOLOGIAN TUTKIMUSKESKUS VTT

Beteiligung beendet

Finnland
Adresse
Tekniikantie 4 A
02044 VTT Espoo

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Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Roland Grafström (Prof.)
ETHNICON METSOVION POLYTECHNION
Griechenland
EU-Beitrag
€ 355 960
Adresse
Heroon Polytechniou 9 Zographou Campus
157 80 Athina

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Georgia Mertzelou (Ms.)
IN SILICO TOXICOLOGY GMBH
Schweiz
EU-Beitrag
€ 519 980
Adresse
Altkircherstrasse 4
4054 Basel

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Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Christoph Helma (Dr.)
IDEACONSULT LIMITED LIABILITY COMPANY
Bulgarien
EU-Beitrag
€ 373 840
Adresse
Angel Kanchev 4
1000 Sofia

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Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Luben Boyanov (Dr.)
KAROLINSKA INSTITUTET
Schweden
EU-Beitrag
€ 257 700
Adresse
Nobels Vag 5
17177 Stockholm

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Per-Olof Larsson (Mr.)
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY

Beteiligung beendet

Finnland
EU-Beitrag
€ 36 018,42
Adresse
Tekniikantie 21
02150 Espoo

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Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Roland Grafström (Prof.)
EUROPEAN MOLECULAR BIOLOGY LABORATORY
Deutschland
EU-Beitrag
€ 372 080
Adresse
Meyerhofstrasse 1
69117 Heidelberg

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Aktivitätstyp
Research Organisations
Kontakt Verwaltung
Phil Irving (Dr.)
UNIVERSITEIT MAASTRICHT
Niederlande
EU-Beitrag
€ 843 334,40
Adresse
Minderbroedersberg 4
6200 MD Maastricht

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Aktivitätstyp
Higher or Secondary Education Establishments
Kontakt Verwaltung
Joseph Ih Janssen (Dr.)
MISVIK BIOLOGY OY
Finnland
EU-Beitrag
€ 361 731,58
Adresse
Karjakatu 35 B
20520 Turku

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Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Kontakt Verwaltung
Vesa Hongisto (Dr.)