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Development of corneal biomechanical model. Dynamic topographical characterization based on 3D plenoptic imaging

Objective

Uncorrected refractive errors are the second leading cause of blindness. Procedures detecting and correcting those errors, such as regular eye exams, glasses or contact lenses or refractive laser based surgery, could thereby transform the lives of millions of people. It is known that successful laser based refractive eye surgery can reduce or even cure common vision refractive errors, as well as, degenerative disorders like keratoconus, which is due to a corneal disorder. But while refractive surgery is becoming more affordable and safer, results are not as successful as they should be. As a consequence, this technique might not be recommendable for everybody, thus a detailed patient evaluation of his or her cornea should be made before deciding whether a refractive laser based surgery is adequate or not.

Based on this fact, the main objective of the POPCORN project is to develop a non-invasive and accurate corneal prediction system. This system will be based on a new imaging technology that will generate a personalised and in-vivo biomechanical model of the patient's cornea. This model will be used to predict the biomechanical behaviour and status of the cornea after surgery. This will allow detecting and avoiding possible risks and negative side effects that could lead to the need of further additional treatments or even, long-term consequences in the visual health of the patients.

This technology development will be possible thanks to the introduction of plenoptic imaging techniques that will allow generating the specific in-vivo patient model without any invasive technique. This will increase the comfort of the evaluation, while being highly accurate and providing precise diagnosis of corneal diseases. Until now, assessing the biomechanical properties of corneal tissue has not been possible besides measuring the Corneal Hysteresis parameter through an Ocular Response Analyser (ORA). This restrains practitioners and researchers from measuring nothing but merely geometrical aspects of the cornea, such as thickness and topography. The newly developed POPCORN system will allow a meticulous evaluation of patients before a laser based surgical procedure, avoiding future negative long-term side effects or patients being wrongly reoriented to other not as effective treatments.

Field of science

  • /medical and health sciences/clinical medicine/surgery
  • /natural sciences/physical sciences/astronomy/planetary science/planetary geology
  • /medical and health sciences/clinical medicine/ophthalmology
  • /medical and health sciences/clinical medicine/surgery/surgical procedure
  • /natural sciences/physical sciences/optics/laser physics

Call for proposal

FP7-SME-2013
See other projects for this call

Funding Scheme

BSG-SME - Research for SMEs

Coordinator

ALICANTE OFTALMOLOGICA SL
Address
Avenida Denia 78
03016 Alicante
Spain
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 120 403,53
Administrative Contact
David Piñero (Dr.)

Participants (7)

COSTRUZIONI STRUMENTI OFTALMICI C.S.O. SRL
Italy
EU contribution
€ 335 375,47
Address
Via Degli Stagnacci 12 E
50018 Badia A Settimo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Riccardo Nicoletti (Mr.)
BIOTRONICS 3D LIMITED
United Kingdom
EU contribution
€ 348 930,42
Address
5 Greenwich View Place City Reach Third Floor Suite D
E14 9NN London
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Haralambos Hatzakis (Mr.)
OPTOELECTRONICA - 2001 SA
Romania
EU contribution
€ 126 863,96
Address
Bd Tudor Vladimirescu 22 Green Gate Offices Fl 8
050880 Bucharest
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Mirela Trupina (Ms)
ASOCIATION INDUSTRIAL DE OPTICA COLOR E IMAGEN (AIDO)

Participation ended

Spain
EU contribution
€ 3 739,37
Address
Calle Nicolas Copernico 7 Parque Tecnologico
46980 Paterna, Valencia
Activity type
Research Organisations
Administrative Contact
Elena Boronat Peidro (Ms.)
UNIVERSIDAD DE ZARAGOZA
Spain
EU contribution
€ 7 985
Address
Calle Pedro Cerbuna 12
50009 Zaragoza
Activity type
Higher or Secondary Education Establishments
Administrative Contact
óscar López (Mr.)
THE UK INTELLIGENT SYSTEMS RESEARCH INSTITUTE LIMITED
United Kingdom
EU contribution
€ 20 394
Address
Pera Business Park Nottingham Road
LE13 0PB Melton Mowbray
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Paul Tattersall (Mr.)
VISIONSENSE LTD

Participation ended

Israel
Address
Hamagshimim Street 20
49348 Petach-tikva
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Avi Yaron (Mr.)