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Molecular Mechanisms of Fungal Pathogen Host Interactions

Objective

ImResFun shall provide state-of-the-art training in infectious disease research and medical immunology targeting the most common human fungal pathogens, the opportunistic Candida species. The key objectives of ImResFun are: (i) to understand how immune cells and infected organs respond to invasion by Candida spp, (ii) to decipher host-defense mechanisms mediating pathogen elimination, and (iii) to identify genetic networks driving the dynamics of host-pathogen interplay. ImResFun will exploit cutting-edge technologies to unravel the basic mechanisms of fungal pathogenesis and host immunity, and to improve diagnosis and identify novel biomarkers of infection. Importantly, ImResFun will translate research into clinical practice and identify potential targets for antifungal drug discovery. ImResFun has seven WPs. In addition to coordination (WP7), research will cover molecular mechanisms of host-pathogen interactions using dual-system infection biology in vitro and in vivo (WP1), clinical patient setting and age-related infections (WP2), chemical biology and antifungal drug development (WP3), and bioinformatics and genome-wide data analysis (WP4). A compulsory and tailor-made practical course (WP5) and complementary skills (WP6) program will boost hypothesis-driven projects. Meaningful exposure to the private sector is ensured by extensive secondments of all ESRs/ERs. The resulting reciprocal technology transfer will be beneficial for both SMEs and ESR/ER hosts and sustain collaborations among partners. ImResFun will use personalized career development plans for each ESR/ER to train entrepreneurial scientists capable of translating frontier research into clinical practice, biotechnology and drug discovery. Taken together, ImResFun offers a best-practice example for interdisciplinary, intersectorial and supradisciplinary training in understanding the immunology of microbial infectious diseases, since most approaches are amenable to other microbial pathogens.

Call for proposal

FP7-PEOPLE-2013-ITN
See other projects for this call

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Address
Spitalgasse 23
1090 Wien
Austria
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 843 298,10
Administrative Contact
Graham Warren (Prof.)

Participants (11)

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 412 869,60
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
Administrative Contact
Christoph Schulte (Mr.)
STOCKHOLMS UNIVERSITET
Sweden
EU contribution
€ 259 925,16
Address
Universitetsvagen 10
10691 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Per Ljungdahl (Prof.)
UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
Germany
EU contribution
€ 222 068,88
Address
Robert-koch-strasse 40
37075 Goettingen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christiane Hennecke (Mrs.)
KING'S COLLEGE LONDON
United Kingdom
EU contribution
€ 285 056,64
Address
Strand
WC2R 2LS London
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Labbett (Mr.)
FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE (VVI)
Czechia
EU contribution
€ 205 208,52
Address
Videnska 1083
142 20 Praha 4
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tereza Madle (Dr.)
EMC MICROCOLLECTIONS GMBH
Germany
EU contribution
€ 222 068,88
Address
Sindelfinger Str. 3
72070 Tuebingen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Renate Spohn (Dr.)
UNIVERSIDAD COMPLUTENSE DE MADRID
Spain
EU contribution
€ 226 681,62
Address
Avenida De Seneca 2
28040 Madrid
Activity type
Higher or Secondary Education Establishments
Administrative Contact
María Isabel Rodriguez Villa (Mrs.)
SZEGEDI TUDOMANYEGYETEM
Hungary
EU contribution
€ 197 255,52
Address
Dugonics Ter 13
6720 Szeged
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Attila Gacser (Dr.)
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
EU contribution
€ 226 681,62
Address
Carrer Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
Administrative Contact
Toni Gabaldón (Dr.)
LABDIA LABORDIAGNOSTIK GMBH
Austria
EU contribution
€ 240 201,72
Address
Zimmermannplatz 8
1090 Wien
Activity type
Other
Administrative Contact
Andrade Nuno (Dr.)
QIAGEN AARHUS AS
Denmark
EU contribution
€ 250 198,74
Address
Silkeborgvej 2
8000 Aarhus
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Thomas Knudsen (Mr.)