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Biodiversity Informatics and Technology Exchange for Snakebite management

Objective

"India is a global hotspot for snakebite mortality, yet management of this significant public health issue requires substantial improvement. Many problems arise from lack of knowledge of the biology of biting species, and much remains to be learned about taxonomy, distribution, and venom characteristics of species such as Russell’s viper (widely considered to be the most dangerous snake in the world). This project will address four main research areas with fundamental gaps in knowledge, to provide a basis for subsequent improvement in clinical treatment and antivenin formulation. The project will synergistically combine EU experts in taxonomy and barcoding of venomous snakes (Bangor; SGN), proteomics of snake venom (CISC, SGN), and transcriptomics of venom glands (Bangor, CSIC, SGN) with corresponding centres of activity in India, including taxonomy and phylogeography at IISC (Bangalore), snake venom proteomics at Sastra (Tamil Nadu), transcriptomics and antivenomics at Tezpur (Assam). Involving both early-stage and experienced researchers, this project will address priorities such as identification of the species responsible for bites in the north-eastern region, where the so-called “Big Four” species (against which antivenin is currently raised in India) are mostly absent, as well as establishing the basis for reference collections of species and their venoms. Several workshops will be run in India to disseminate best practice, training in taxonomic and ""omic"" technology and analyses among early researchers. In turn, Indian partners will second experienced and early-stage staff to the EU for longer-term training in state-of-the-art techniques (such as next-generation approaches to transcriptomics and genomics). This partnership will also form the basis for further collaborative applications to address wider issues such as the use of venom components as drug leads, the evolution of snake venom, as well as application of knowledge gained for snakebite management."

Field of science

  • /medical and health sciences/health sciences/public and environmental health
  • /social sciences/sociology/demography/mortality
  • /natural sciences/biological sciences/biochemistry/biomolecules/proteins/proteomics

Call for proposal

FP7-PEOPLE-2013-IRSES
See other projects for this call

Funding Scheme

MC-IRSES - International research staff exchange scheme (IRSES)

Coordinator

BANGOR UNIVERSITY
Address
College Road
LL57 2DG Bangor
United Kingdom
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 96 600
Administrative Contact
Clare Williams (Mrs.)

Participants (3)

JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN
Germany
EU contribution
€ 33 600
Address
Theodor W Adorno Platz 1
60323 Frankfurt Am Main
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Susanne Wothke
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 33 600
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
María ángeles López Vázquez (Ms.)
SENCKENBERG GESELLSCHAFT FUR NATURFORSCHUNG

Participation ended

Germany
Address
Senckenberganlage 25
60325 Frankfurt
Activity type
Other
Administrative Contact
Johannes Heilmann (Dr.)