Objetivo We aim to commercialise a new, patent-protected concept to measure mechanical properties of biological cells with flow-cytometer-level throughput and establish its standard application in modern drug development and medical diagnostics. Mechanical properties have recently proven to be a physiologically relevant indicator to determine the state, function and type of biological cells. Analysing mechanical parameters provides a novel method to identify physiological or pathological changes. However, mechanical cell properties are currently not accessible for large-scale applications demanding high-throughput. We developed, designed and realised a hydrodynamic cell stretcher, a microfluidic-based device for analysing mechanical cell properties at rates above 100 cells per second and therefore three orders of magnitude faster than other existing methods. In the proposed project, we want to identify, test and validate the most promising applications of hydrodynamic cell stretching in clinical and pharmaceutical research. Ámbito científico medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery Programa(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) ERC-OA-2013-PoC - European Research Council ERC Proof of Concept Convocatoria de propuestas ERC-2013-PoC Consulte otros proyectos de esta convocatoria Régimen de financiación CSA-SA(POC) - Supporting action (Proof of Concept) Institución de acogida TECHNISCHE UNIVERSITAET DRESDEN Aportación de la UE € 149 549,84 Dirección HELMHOLTZSTRASSE 10 01069 Dresden Alemania Ver en el mapa Región Sachsen Dresden Dresden, Kreisfreie Stadt Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Friederieke Noack (Mrs.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Beneficiarios (1) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo TECHNISCHE UNIVERSITAET DRESDEN Alemania Aportación de la UE € 149 549,84 Dirección HELMHOLTZSTRASSE 10 01069 Dresden Ver en el mapa Región Sachsen Dresden Dresden, Kreisfreie Stadt Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Friederieke Noack (Mrs.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos
