Obiettivo We aim to commercialise a new, patent-protected concept to measure mechanical properties of biological cells with flow-cytometer-level throughput and establish its standard application in modern drug development and medical diagnostics. Mechanical properties have recently proven to be a physiologically relevant indicator to determine the state, function and type of biological cells. Analysing mechanical parameters provides a novel method to identify physiological or pathological changes. However, mechanical cell properties are currently not accessible for large-scale applications demanding high-throughput. We developed, designed and realised a hydrodynamic cell stretcher, a microfluidic-based device for analysing mechanical cell properties at rates above 100 cells per second and therefore three orders of magnitude faster than other existing methods. In the proposed project, we want to identify, test and validate the most promising applications of hydrodynamic cell stretching in clinical and pharmaceutical research. Campo scientifico medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery Programma(i) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) ERC-OA-2013-PoC - European Research Council ERC Proof of Concept Invito a presentare proposte ERC-2013-PoC Vedi altri progetti per questo bando Meccanismo di finanziamento CSA-SA(POC) - Supporting action (Proof of Concept) Istituzione ospitante TECHNISCHE UNIVERSITAET DRESDEN Contributo UE € 149 549,84 Indirizzo HELMHOLTZSTRASSE 10 01069 Dresden Germania Mostra sulla mappa Regione Sachsen Dresden Dresden, Kreisfreie Stadt Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Friederieke Noack (Mrs.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Beneficiari (1) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto TECHNISCHE UNIVERSITAET DRESDEN Germania Contributo UE € 149 549,84 Indirizzo HELMHOLTZSTRASSE 10 01069 Dresden Mostra sulla mappa Regione Sachsen Dresden Dresden, Kreisfreie Stadt Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Friederieke Noack (Mrs.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato
