High-throughput real-time characterisation of cell-mechanical properties

Projektinformationen

FASTTOUCH

ID Finanzhilfevereinbarung: 632222

Projekt abgeschlossen

Startdatum 1 Juli 2014

Enddatum 31 Dezember 2015

Finanziert unter

• Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 165 775,60

EU-Beitrag € 149 549,84

Koordiniert durch

TECHNISCHE UNIVERSITAET DRESDEN
Germany

Ziel

We aim to commercialise a new, patent-protected concept to measure mechanical properties of biological cells with flow-cytometer-level throughput and establish its standard application in modern drug development and medical diagnostics. Mechanical properties have recently proven to be a physiologically relevant indicator to determine the state, function and type of biological cells. Analysing mechanical parameters provides a novel method to identify physiological or pathological changes. However, mechanical cell properties are currently not accessible for large-scale applications demanding high-throughput. We developed, designed and realised a hydrodynamic cell stretcher, a microfluidic-based device for analysing mechanical cell properties at rates above 100 cells per second and therefore three orders of magnitude faster than other existing methods. In the proposed project, we want to identify, test and validate the most promising applications of hydrodynamic cell stretching in clinical and pharmaceutical research.

Wissenschaftliches Gebiet

• medical and health sciences › basic medicine › pharmacology and pharmacy › drug discovery

Programm/Programme

• FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• ERC-OA-2013-PoC - European Research Council ERC Proof of Concept

Aufforderung zur Vorschlagseinreichung

ERC-2013-PoC
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

CSA-SA(POC) - Supporting action (Proof of Concept)

Gastgebende Einrichtung

TECHNISCHE UNIVERSITAET DRESDEN

Kontakt Verwaltung

Friederieke Noack (Mrs.)

• EU-Beitrag: € 149 549,84
• Adresse: HELMHOLTZSTRASSE 10 ; 01069 Dresden ; Deutschland
• Region: Sachsen › Dresden › Dresden, Kreisfreie Stadt
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten

Begünstigte (1)

TECHNISCHE UNIVERSITAET DRESDEN

Deutschland

Kontakt Verwaltung

Friederieke Noack (Mrs.)

• EU-Beitrag: € 149 549,84
• Adresse: HELMHOLTZSTRASSE 10 ; 01069 Dresden
• Region: Sachsen › Dresden › Dresden, Kreisfreie Stadt
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten