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Strengthening Animal Production and Health through the Immune Response

Objective

SAPHIR aims to develop vaccine strategies effective against endemic pathogens responsible for high economic losses in livestock in order to strengthen the profitability of food animal systems, improve animal welfare and reduce xenobiotic usage in farming with a One Health perspective.

SAPHIR will bring novel vaccine strategies to the market i) at short term, with several promising vaccines brought to demonstration (RTL6), ii) at long term, with cutting edge strategies brought at proof of concept (RTL3) and iii) in line with socio-economic requirements. SAPHIR has selected two representative pathogens of pigs (Porcine Reproductive and Respiratory Syndrome Virus and Mycoplasma hyopneumoniae), chickens (Eimeria and Clostridium perfringens) and cattle (Bovine Respiratory Syncytial Virus, Mycoplasma bovis) to develop generic vaccine approaches applicable to other pathogens.

SAPHIR will issue i) knowledge of immune mechanisms of protection, ii) affordable, safe and multivalent vaccines with DIVA properties, iii) efficient adjuvants targeting dendritic cells, optimal formulations, new mucosal and skin delivery systems, a new generation of DNA vectors and viral replicon platforms for fostering an earlier and longer duration of immunity including the perinatal period, and iv) basal biomarkers of individual immuno-competence for future breeding strategies. The SAPHIR dissemination and training programme includes creation of an integrated health management website, launch of a Global Alliance for Veterinary Vaccines and organization of workshops directed at food animal system stakeholders. This will ensure optimal research translation of SAPHIR outputs to market and field applications.
SAPHIR brings together interdisciplinary expertise from fourteen academic institutes including a Chinese partner, five SMEs and two pharmaceutical companies.

Field of science

  • /social sciences/economics and business/business and management/commerce
  • /engineering and technology/other engineering and technologies/food and beverages
  • /natural sciences/biological sciences/genetics and heredity/dna
  • /agricultural sciences/animal and dairy science/animal husbandry
  • /agricultural sciences/veterinary science

Call for proposal

H2020-SFS-2014-2
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
Address
147 Rue De L'universite
75007 Paris Cedex 07
France
Activity type
Research Organisations
EU contribution
€ 2 191 579,38

Participants (21)

CARDIFF UNIVERSITY
United Kingdom
EU contribution
€ 319 743,75
Address
Newport Road 30-36
CF24 ODE Cardiff
Activity type
Higher or Secondary Education Establishments
EIDGENOESSISCHES DEPARTEMENT DES INNERN
Switzerland
EU contribution
€ 1 200
Address
Inselgasse 1
3003 Bern
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
EUROPEAN FORUM OF FARM ANIMAL BREEDERS
Netherlands
EU contribution
€ 150 893,75
Address
Dreijenlaan 2K 1060 1061
6703 HA Wageningen
Activity type
Research Organisations
INMUNOLOGIA Y GENETICA APLICADA SA
Spain
EU contribution
€ 445 193,75
Address
C/ Hermanos Garcia Noblejas 41-2
28037 Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INRAE TRANSFERT SAS
France
EU contribution
€ 365 176,25
Address
Rue Du Docteur Finlay 28
75015 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PARCO TECNOLOGICO PADANO S.R.L.
Italy
EU contribution
€ 278 868,75
Address
Via Einstein - Localita Cascina Codazza
26900 Lodi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Shanghai Veterinary Research Institute - Chinese Academy of Agricultural Sciences
China
EU contribution
€ 0
Address
Ziyue Road 518
200241 Shanghai
Activity type
Research Organisations
SPOREGEN LIMITED
United Kingdom
EU contribution
€ 224 993,75
Address
Queens Road 3 Westley Gate
RG1 4AP Reading Berkshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STICHTING WAGENINGEN RESEARCH
Netherlands
EU contribution
€ 772 092,50
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Research Organisations
SVERIGES LANTBRUKSUNIVERSITET
Sweden
EU contribution
€ 323 788,75
Address
Almas Alle 8
750 07 Uppsala
Activity type
Higher or Secondary Education Establishments
SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO
Poland
EU contribution
€ 92 731,25
Address
Ul. Nowoursynowska 166
02 787 Warszawa
Activity type
Higher or Secondary Education Establishments
THE PIRBRIGHT INSTITUTE LBG
United Kingdom
EU contribution
€ 289 067,50
Address
Ash Road Pirbright
GU24 0NF Woking
Activity type
Research Organisations
THE ROYAL VETERINARY COLLEGE
United Kingdom
EU contribution
€ 458 846,25
Address
Royal College Street
NW1 OTU London
Activity type
Higher or Secondary Education Establishments
UNIVERSITAET BERN
Switzerland
EU contribution
€ 31 437,50
Address
Hochschulstrasse 6
3012 Bern
Activity type
Higher or Secondary Education Establishments
UNIVERSITE DE LAUSANNE
Switzerland
EU contribution
€ 0
Address
Quartier Unil-centre Bâtiment Unicentre
1015 Lausanne
Activity type
Higher or Secondary Education Establishments
UNIVERSITEIT GENT
Belgium
EU contribution
€ 1 234 978,50
Address
Sint Pietersnieuwstraat 25
9000 Gent
Activity type
Higher or Secondary Education Establishments
THE UNIVERSITY OF EDINBURGH
United Kingdom
EU contribution
€ 802 187,19
Address
Old College, South Bridge
EH8 9YL Edinburgh
Activity type
Higher or Secondary Education Establishments
VACCIBODY AS
Norway
EU contribution
€ 334 368,75
Address
Gaustadalleen 21
0349 Oslo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VIRBAC SA
France
EU contribution
€ 0
Address
Rue 13Eme Lid
06511 Carros
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
XEOLAS PHARMACEUTICALS LIMITED
Ireland
EU contribution
€ 391 993,68
Address
97 Furry Park Road
5 Killester
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE UNIVERSITY OF LIVERPOOL
United Kingdom
EU contribution
€ 290 855
Address
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool
Activity type
Higher or Secondary Education Establishments