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Strengthening Animal Production and Health through the Immune Response

Objetivo

SAPHIR aims to develop vaccine strategies effective against endemic pathogens responsible for high economic losses in livestock in order to strengthen the profitability of food animal systems, improve animal welfare and reduce xenobiotic usage in farming with a One Health perspective.

SAPHIR will bring novel vaccine strategies to the market i) at short term, with several promising vaccines brought to demonstration (RTL6), ii) at long term, with cutting edge strategies brought at proof of concept (RTL3) and iii) in line with socio-economic requirements. SAPHIR has selected two representative pathogens of pigs (Porcine Reproductive and Respiratory Syndrome Virus and Mycoplasma hyopneumoniae), chickens (Eimeria and Clostridium perfringens) and cattle (Bovine Respiratory Syncytial Virus, Mycoplasma bovis) to develop generic vaccine approaches applicable to other pathogens.

SAPHIR will issue i) knowledge of immune mechanisms of protection, ii) affordable, safe and multivalent vaccines with DIVA properties, iii) efficient adjuvants targeting dendritic cells, optimal formulations, new mucosal and skin delivery systems, a new generation of DNA vectors and viral replicon platforms for fostering an earlier and longer duration of immunity including the perinatal period, and iv) basal biomarkers of individual immuno-competence for future breeding strategies. The SAPHIR dissemination and training programme includes creation of an integrated health management website, launch of a Global Alliance for Veterinary Vaccines and organization of workshops directed at food animal system stakeholders. This will ensure optimal research translation of SAPHIR outputs to market and field applications.
SAPHIR brings together interdisciplinary expertise from fourteen academic institutes including a Chinese partner, five SMEs and two pharmaceutical companies.

Convocatoria de propuestas

H2020-SFS-2014-2
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Coordinador

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
Dirección
147 Rue De L'universite
75007 Paris Cedex 07
Francia
Tipo de actividad
Research Organisations
Aportación de la UE
€ 2 191 579,38

Participantes (21)

CARDIFF UNIVERSITY
United Kingdom
Aportación de la UE
€ 319 743,75
Dirección
Newport Road 30-36
CF24 ODE Cardiff
Tipo de actividad
Higher or Secondary Education Establishments
EIDGENOESSISCHES DEPARTEMENT DES INNERN
Suiza
Aportación de la UE
€ 1 200
Dirección
Inselgasse 1
3003 Bern
Tipo de actividad
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
EUROPEAN FORUM OF FARM ANIMAL BREEDERS
Países Bajos
Aportación de la UE
€ 150 893,75
Dirección
Silkeborg 75
2905 AT Capelle Aan Den Ijssel
Tipo de actividad
Research Organisations
EUROFINS INGENASA SA
España
Aportación de la UE
€ 445 193,75
Dirección
Avenida Institucion Libre De La Ensenaza 41
28037 Madrid
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INRAE TRANSFERT SAS
Francia
Aportación de la UE
€ 365 176,25
Dirección
Rue Du Docteur Finlay 28
75015 Paris
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PARCO TECNOLOGICO PADANO S.R.L.
Italia
Aportación de la UE
€ 278 868,75
Dirección
Via Einstein - Localita Cascina Codazza
26900 Lodi
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Shanghai Veterinary Research Institute - Chinese Academy of Agricultural Sciences
China
Aportación de la UE
€ 0
Dirección
Ziyue Road 518
200241 Shanghai
Tipo de actividad
Research Organisations
SPOREGEN LIMITED
United Kingdom
Aportación de la UE
€ 224 993,75
Dirección
Queens Road 3 Westley Gate
RG1 4AP Reading Berkshire
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STICHTING WAGENINGEN RESEARCH
Países Bajos
Aportación de la UE
€ 772 092,50
Dirección
Droevendaalsesteeg 4
6708 PB Wageningen
Tipo de actividad
Research Organisations
SVERIGES LANTBRUKSUNIVERSITET
Suecia
Aportación de la UE
€ 323 788,75
Dirección
Almas Alle 8
750 07 Uppsala
Tipo de actividad
Higher or Secondary Education Establishments
SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO
Polonia
Aportación de la UE
€ 92 731,25
Dirección
Ul. Nowoursynowska 166
02 787 Warszawa
Tipo de actividad
Higher or Secondary Education Establishments
THE PIRBRIGHT INSTITUTE LBG
United Kingdom
Aportación de la UE
€ 289 067,50
Dirección
Ash Road Pirbright
GU24 0NF Woking
Tipo de actividad
Research Organisations
THE ROYAL VETERINARY COLLEGE
United Kingdom
Aportación de la UE
€ 458 846,25
Dirección
Royal College Street
NW1 OTU London
Tipo de actividad
Higher or Secondary Education Establishments
UNIVERSITAET BERN
Suiza
Aportación de la UE
€ 31 437,50
Dirección
Hochschulstrasse 6
3012 Bern
Tipo de actividad
Higher or Secondary Education Establishments
UNIVERSITE DE LAUSANNE
Suiza
Aportación de la UE
€ 0
Dirección
Quartier Unil-centre Bâtiment Unicentre
1015 Lausanne
Tipo de actividad
Higher or Secondary Education Establishments
UNIVERSITEIT GENT
Bélgica
Aportación de la UE
€ 1 234 978,50
Dirección
Sint Pietersnieuwstraat 25
9000 Gent
Tipo de actividad
Higher or Secondary Education Establishments
THE UNIVERSITY OF EDINBURGH
United Kingdom
Aportación de la UE
€ 802 187,19
Dirección
Old College, South Bridge
EH8 9YL Edinburgh
Tipo de actividad
Higher or Secondary Education Establishments
VACCIBODY AS
Noruega
Aportación de la UE
€ 334 368,75
Dirección
Gaustadalleen 21
0349 Oslo
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VIRBAC SA
Francia
Aportación de la UE
€ 0
Dirección
Rue 13Eme Lid
06511 Carros
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
XEOLAS PHARMACEUTICALS LIMITED
Irlanda
Aportación de la UE
€ 391 993,68
Dirección
97 Furry Park Road
5 Killester
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
THE UNIVERSITY OF LIVERPOOL
United Kingdom
Aportación de la UE
€ 290 855
Dirección
Brownlow Hill 765 Foundation Building
L69 7ZX Liverpool
Tipo de actividad
Higher or Secondary Education Establishments