Objective
The decision-making in chemotherapy nowadays depends on standard methods that are liquid chromatography (LC-MS/MS) followed by mass spectrometry or capillary electrophoresis; both are labour- and cost-intensive and can be performed only in dedicated hospitals and laboratories. This lead to a minimal therapeutic drug monitoring in patients and hence that 30-60% of drugs are administered without clinical benefits.
We propose to develop a point-of-care device for quantification of chemotherapeutic drugs in small body fluid samples by highly selective nanoparticle extraction and liquid crystal detection incorporated in microfluidic lab-on-chip device (optofluidics based) allowing the real-time drug monitoring. This will improve the therapeutic outcome and reduced health care costs.
Fields of science
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
70013 Castellana Grotte Ba
Italy
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Participants (10)
48149 Muenster
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7521 AN Enschede
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
33081 Aviano Pn
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48149 Muenster
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1015 Lausanne
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WC1E 6BT London
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Participation ended
85604 Zorneding
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Participation ended
20133 Milano
Participation ended
70126 Bari
83607 Holzkirchen
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