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Professional cross-priming for ovary and prostate cancer

Deliverables

PROCROP Logo, graphical Chart and webpage

Design of the official PROCROP logo and graphical chart to generate visual identity for the project. Also, an official webpage will be created for PROCROP, to inform public and scientific community about different issues related to the project.

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Publications

Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation

Author(s): Carlos del Fresno, Salvador Iborra, Paula Saz-Leal, María Martínez-López, David Sancho
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.00804

Dectin-1/2–induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses

Author(s): Maria M. M. Kaisar, Manuel Ritter, Carlos del Fresno, Hulda S. Jónasdóttir, Alwin J. van der Ham, Leonard R. Pelgrom, Gabriele Schramm, Laura E. Layland, David Sancho, Clarissa Prazeres da Costa, Martin Giera, Maria Yazdanbakhsh, Bart Everts
Published in: PLOS Biology, Issue 16/4, 2018, Page(s) e2005504, ISSN 1545-7885
DOI: 10.1371/journal.pbio.2005504

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells

Author(s): Michel Enamorado, Salvador Iborra, Elena Priego, Francisco J. Cueto, Juan A. Quintana, Sarai Martínez-Cano, Ernesto Mejías-Pérez, Mariano Esteban, Ignacio Melero, Andrés Hidalgo, David Sancho
Published in: Nature Communications, Issue 8, 2017, Page(s) 16073, ISSN 2041-1723
DOI: 10.1038/ncomms16073

Innate Immune Function of Mitochondrial Metabolism

Author(s): David Sancho, Michel Enamorado, Johan Garaude
Published in: Frontiers in Immunology, Issue 8, 2017, ISSN 1664-3224
DOI: 10.3389/fimmu.2017.00527

Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4–1BB)

Author(s): Arantza Azpilikueta, Elixabet Bolaños, Valerie Lang, Sara Labiano, Maria A. Aznar, Iñaki Etxeberria, Alvaro Teijeira, Maria E. Rodriguez-Ruiz, Jose L. Perez-Gracia, Maria Jure-Kunkel, Juan M. Zapata, Manuel S. Rodriguez, Ignacio Melero
Published in: OncoImmunology, Issue 7/1, 2017, Page(s) e1368605, ISSN 2162-402X
DOI: 10.1080/2162402X.2017.1368605

Antitumor effect of an adeno-associated virus expressing apolipoprotein A-1 fused to interferon alpha in an interferon alpha-resistant murine tumor model

Author(s): Marcos Vasquez, Vladimir Paredes-Cervantes, Fernando Aranda, Nuria Ardaiz, Celia Gomar, Pedro Berraondo
Published in: Oncotarget, Issue 8/3, 2017, ISSN 1949-2553
DOI: 10.18632/oncotarget.14127

Immune Curbing of Cancer Stem Cells by CTLs Directed to NANOG

Author(s): Christina Wefers, Gerty Schreibelt, Leon F. A. G. Massuger, I. Jolanda M. de Vries, Ruurd Torensma
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
DOI: 10.3389/fimmu.2018.01412

Different Lipid Regulation in Ovarian Cancer: Inhibition of the Immune System

Author(s): Christina Wefers, Tjitske Duiveman-de Boer, Petra Zusterzeel, Leon Massuger, David Fuchs, Ruurd Torensma, Craig Wheelock, I. de Vries
Published in: International Journal of Molecular Sciences, Issue 19/1, 2018, Page(s) 273, ISSN 1422-0067
DOI: 10.3390/ijms19010273

Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells

Author(s): A. R. Sanchez-Paulete, F. J. Cueto, M. Martinez-Lopez, S. Labiano, A. Morales-Kastresana, M. E. Rodriguez-Ruiz, M. Jure-Kunkel, A. Azpilikueta, M. A. Aznar, J. I. Quetglas, D. Sancho, I. Melero
Published in: Cancer Discovery, Issue 6/1, 2016, Page(s) 71-79, ISSN 2159-8274
DOI: 10.1158/2159-8290.CD-15-0510

Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense

Author(s): Johan Garaude, Rebeca Acín-Pérez, Sarai Martínez-Cano, Michel Enamorado, Matteo Ugolini, Estanislao Nistal-Villán, Sandra Hervás-Stubbs, Pablo Pelegrín, Leif E Sander, José A Enríquez, David Sancho
Published in: Nature Immunology, Issue 17/9, 2016, Page(s) 1037-1045, ISSN 1529-2908
DOI: 10.1038/ni.3509

Making the Most of Cancer Surgery with Neoadjuvant Immunotherapy

Author(s): I. Melero, P. Berraondo, M. E. Rodriguez-Ruiz, J. L. Perez-Gracia
Published in: Cancer Discovery, Issue 6/12, 2016, Page(s) 1312-1314, ISSN 2159-8274
DOI: 10.1158/2159-8290.CD-16-1109

Anti-CD137 monoclonal antibodies and adoptive T cell therapy: a perfect marriage?

Author(s): Bettina Weigelin, Elixabet Bolaños, Maria E. Rodriguez-Ruiz, Ivan Martinez-Forero, Peter Friedl, Ignacio Melero
Published in: Cancer Immunology, Immunotherapy, Issue 65/5, 2016, Page(s) 493-497, ISSN 0340-7004
DOI: 10.1007/s00262-016-1818-5

Interferon alpha bioactivity critically depends on Scavenger receptor class B type I function

Author(s): Marcos Vasquez, Jessica Fioravanti, Fernando Aranda, Vladimir Paredes, Celia Gomar, Nuria Ardaiz, Veronica Fernandez-Ruiz, Miriam Méndez, Estanislao Nistal-Villan, Esther Larrea, Qinshan Gao, Gloria Gonzalez-Aseguinolaza, Jesus Prieto, Pedro Berraondo
Published in: OncoImmunology, Issue 5/8, 2016, Page(s) e1196309, ISSN 2162-402X
DOI: 10.1080/2162402X.2016.1196309

Harnessing RNA sequencing for global, unbiased evaluation of two new adjuvants for dendritic-cell immunotherapy

Author(s): Till S.M. Mathan, Johannes Textor, Annette E. Sköld, Inge Reinieren-Beeren, Tom van Oorschot, Mareke Brüning, Carl G. Figdor, Sonja I. Buschow, Ghaith Bakdash, I. Jolanda M. de Vries
Published in: Oncotarget, 2017, ISSN 1949-2553
DOI: 10.18632/oncotarget.15190