Unraveling changes in cellular gene expression during viral infection

Informazioni relative al progetto

Profile Infection

ID dell’accordo di sovvenzione: 638142

DOI 10.3030/638142

Progetto chiuso

Data della firma CE 29 Maggio 2015

Data di avvio 1 Giugno 2015

Data di completamento 31 Maggio 2020

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 500 000,00

Contributo UE € 1 500 000,00

Coordinato da

WEIZMANN INSTITUTE OF SCIENCE
Israel

Pubblicazioni

Peer reviewed articles (6)

Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing

Autori: Miri Shnayder, Aharon Nachshon, Benjamin Krishna, Emma Poole, Alina Boshkov, Amit Binyamin, Itay Maza, John Sinclair, Michal Schwartz, Noam Stern-Ginossar
Pubblicato in: mBio, Numero 9/2, 2018, Pagina/e e00013-18, ISSN 2150-7511
Editore: mBio
DOI: 10.1128/mBio.00013-18

A systematic view on influenza induced host shutoff

Autori: Adi Bercovich-Kinori, Julie Tai, Idit Anna Gelbart, Alina Shitrit, Shani Ben-Moshe, Yaron Drori, Shalev Itzkovitz, Michal Mandelboim, Noam Stern-Ginossar
Pubblicato in: eLife, Numero 5, 2016, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/eLife.18311

Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state

Autori: Miri Shnayder, Aharon Nachshon, Batsheva Rozman, Biana Bernshtein, Michael Lavi, Noam Fein, Emma Poole, Selmir Avdic, Emily Blyth, David Gottlieb, Allison Abendroth, Barry Slobedman, John Sinclair, Noam Stern-Ginossar, Michal Schwartz
Pubblicato in: eLife, Numero 9, 2020, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.52168

Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

Autori: Erez Eliyahu, Osnat Tirosh, Martina Dobesova, Aharon Nachshon, Michal Schwartz, Noam Stern-Ginossar
Pubblicato in: Journal of Virology, Numero 93/19, 2019, ISSN 0022-538X
Editore: American Society for Microbiology
DOI: 10.1128/jvi.00453-19

m6A modification controls the innate immune response to infection by targeting type I interferons

Autori: Roni Winkler, Ella Gillis, Lior Lasman, Modi Safra, Shay Geula, Clara Soyris, Aharon Nachshon, Julie Tai-Schmiedel, Nehemya Friedman, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Michal Mandelboim, Jacob H. Hanna, Schraga Schwartz, Noam Stern-Ginossar
Pubblicato in: Nature Immunology, Numero 20/2, 2019, Pagina/e 173-182, ISSN 1529-2908
Editore: Nature Publishing Group
DOI: 10.1038/s41590-018-0275-z

Virus-Induced Changes in mRNA Secondary Structure Uncover cis-Regulatory Elements that Directly Control Gene Expression

Autori: Orel Mizrahi, Aharon Nachshon, Alina Shitrit, Idit A. Gelbart, Martina Dobesova, Shirly Brenner, Chaim Kahana, Noam Stern-Ginossar
Pubblicato in: Molecular Cell, Numero 72/5, 2018, Pagina/e 862-874.e5, ISSN 1097-2765
Editore: Cell Press
DOI: 10.1016/j.molcel.2018.09.003