Antifreeze GlycoProtein Mimetic Polymers

Publications

High-Throughput Tertiary Amine Deoxygenated Photopolymerizations for Synthesizing Polymer Libraries

Author(s): Christopher Stubbs, Thomas Congdon, Jessica Davis, Daniel Lester, Sarah-Jane Richards, Matthew I. Gibson
Published in: Macromolecules, Issue 52/20, 2019, Page(s) 7603-7612, ISSN 0024-9297
Publisher: American Chemical Society
DOI: 10.1021/acs.macromol.9b01714

Synthetically Scalable Poly(ampholyte) Which Dramatically Enhances Cellular Cryopreservation

Author(s): Trisha L. Bailey, Christopher Stubbs, Kathryn Murray, Ruben M. F. Tomás, Lucienne Otten, Matthew I. Gibson
Published in: Biomacromolecules, Issue 20/8, 2019, Page(s) 3104-3114, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.9b00681

Low DMSO Cryopreservation of Stem Cells Enabled by Macromolecular Cryoprotectants

Author(s): Kathryn A. Murray, Ruben M. F. Tomás, Matthew I. Gibson
Published in: ACS Applied Bio Materials, Issue 3/9, 2020, Page(s) 5627-5632, ISSN 2576-6422
Publisher: ACS
DOI: 10.1021/acsabm.0c00638

Double-Modified Glycopolymers from Thiolactones to Modulate Lectin Selectivity and Affinity

Author(s): Laura E. Wilkins, Nezha Badi, Filip Du Prez, Matthew I. Gibson
Published in: ACS Macro Letters, Issue 7/12, 2018, Page(s) 1498-1502, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.8b00825

Extracellular Antifreeze Protein Significantly Enhances the Cryopreservation of Cell Monolayers

Author(s): Ruben M. F. Tomás, Trisha L. Bailey, Muhammad Hasan, Matthew I. Gibson
Published in: Biomacromolecules, Issue 20/10, 2019, Page(s) 3864-3872, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.9b00951

Photochemical “In-Air” Combinatorial Discovery of Antimicrobial Co-polymers

Author(s): Sarah-Jane Richards, Adam Jones, Ruben M. F. Tomás, Matthew I. Gibson
Published in: Chemistry - A European Journal, Issue 24/52, 2018, Page(s) 13758-13761, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201802594

Probing the causes of thermal hysteresis using tunable N agg micelles with linear and brush-like thermoresponsive coronas

Author(s): L. D. Blackman, M. I. Gibson, R. K. O'Reilly
Published in: Polymer Chemistry, Issue 8/1, 2017, Page(s) 233-244, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/C6PY01191H

Antifreeze Protein Mimetic Metallohelices with Potent Ice Recrystallization Inhibition Activity

Author(s): Daniel E. Mitchell, Guy Clarkson, David J. Fox, Rebecca A. Vipond, Peter Scott, Matthew I. Gibson
Published in: Journal of the American Chemical Society, Issue 139/29, 2017, Page(s) 9835-9838, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.7b05822

Evaluation of the Antimicrobial Activity of Cationic Polymers against Mycobacteria: Toward Antitubercular Macromolecules

Author(s): Daniel J. Phillips, James Harrison, Sarah-Jane Richards, Daniel E. Mitchell, Esther Tichauer, Alasdair T. M. Hubbard, Collette Guy, Ian Hands-Portman, Elizabeth Fullam, Matthew I. Gibson
Published in: Biomacromolecules, Issue 18/5, 2017, Page(s) 1592-1599, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.7b00210

Identification of the anti-mycobacterial functional properties of piperidinol derivatives

Author(s): Collette S Guy, Esther Tichauer, Gemma L Kay, Daniel J Phillips, Trisha L Bailey, James Harrison, Christopher M Furze, Andrew D Millard, Matthew I Gibson, Mark J Pallen, Elizabeth Fullam
Published in: British Journal of Pharmacology, Issue 174/14, 2017, Page(s) 2183-2193, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.13744

Regioregular Alternating Polyampholytes Have Enhanced Biomimetic Ice Recrystallization Activity Compared to Random Copolymers and the Role of Side Chain versus Main Chain Hydrophobicity

Author(s): Christopher Stubbs, Julia Lipecki, Matthew I. Gibson
Published in: Biomacromolecules, Issue 18/1, 2016, Page(s) 295-302, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.6b01691

Externally controllable glycan presentation on nanoparticle surfaces to modulate lectin recognition

Author(s): Sangho Won, Sarah-Jane Richards, Marc Walker, Matthew I. Gibson
Published in: Nanoscale Horizons, Issue 2/2, 2017, Page(s) 106-109, ISSN 2055-6756
Publisher: Royal Society of Chemistry
DOI: 10.1039/c6nh00202a

“Grafting to” of RAFTed Responsive Polymers to Glass Substrates by Thiol–Ene and Critical Comparison to Thiol–Gold Coupling

Author(s): Caroline I. Biggs, Marc Walker, Matthew I. Gibson
Published in: Biomacromolecules, Issue 17/8, 2016, Page(s) 2626-2633, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.6b00662

Activation of ice recrystallization inhibition activity of poly(vinyl alcohol) using a supramolecular trigger

Author(s): Daniel J. Phillips, Thomas R. Congdon, Matthew I. Gibson
Published in: Polymer Chemistry, Issue 7/9, 2016, Page(s) 1701-1704, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/c5py01948f

Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms

Author(s): Sarah-Jane Richards, Klea Isufi, Laura E. Wilkins, Julia Lipecki, Elizabeth Fullam, Matthew I. Gibson
Published in: Biomacromolecules, Issue 19/1, 2017, Page(s) 256-264, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.7b01561

Impact of sequential surface-modification of graphene oxide on ice nucleation

Author(s): Caroline I. Biggs, Christopher Packer, Steven Hindmarsh, Marc Walker, Neil R. Wilson, Jonathan P. Rourke, Matthew I. Gibson
Published in: Physical Chemistry Chemical Physics, Issue 19/33, 2017, Page(s) 21929-21932, ISSN 1463-9076
Publisher: Royal Society of Chemistry
DOI: 10.1039/C7CP03219F

Ultralow Dispersity Poly(vinyl alcohol) Reveals Significant Dispersity Effects on Ice Recrystallization Inhibition Activity

Author(s): Nicholas S. Vail, Christopher Stubbs, Caroline I. Biggs, Matthew I. Gibson
Published in: ACS Macro Letters, Issue 6/9, 2017, Page(s) 1001-1004, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00595

Polyproline as a Minimal Antifreeze Protein Mimic That Enhances the Cryopreservation of Cell Monolayers

Author(s): Ben Graham, Trisha L. Bailey, Joseph R. J. Healey, Moreno Marcellini, Sylvain Deville, Matthew I. Gibson
Published in: Angewandte Chemie International Edition, Issue 56/50, 2017, Page(s) 15941-15944, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201706703

Structure-activity relationship of the exopolysaccharide from a psychrophilic bacterium: A strategy for cryoprotection

Author(s): Angela Casillo, Ermenegilda Parrilli, Filomena Sannino, Daniel E. Mitchell, Matthew I. Gibson, Gennaro Marino, Rosa Lanzetta, Michelangelo Parrilli, Sandro Cosconati, Ettore Novellino, Antonio Randazzo, Maria L. Tutino, M. Michela Corsaro
Published in: Carbohydrate Polymers, Issue 156, 2017, Page(s) 364-371, ISSN 0144-8617
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2016.09.037

Polymer mimics of biomacromolecular antifreezes

Author(s): Caroline I. Biggs, Trisha L. Bailey, Ben Graham, Christopher Stubbs, Alice Fayter, Matthew I. Gibson
Published in: Nature Communications, Issue 8/1, 2017, Page(s) 1546, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-01421-7

Synthesis of Degradable Poly(vinyl alcohol) by Radical Ring-Opening Copolymerization and Ice Recrystallization Inhibition Activity

Author(s): Guillaume Hedir, Christopher Stubbs, Phillip Aston, Andrew P. Dove, Matthew I. Gibson
Published in: ACS Macro Letters, Issue 6/12, 2017, Page(s) 1404-1408, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00905

Facially Amphipathic Glycopolymers Inhibit Ice Recrystallization

Author(s): Ben Graham, Alice E. R. Fayter, Judith E. Houston, Rachel C. Evans, Matthew I. Gibson
Published in: Journal of the American Chemical Society, Issue 140/17, 2018, Page(s) 5682-5685, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.8b02066

Triggerable Multivalent Glyconanoparticles for Probing Carbohydrate–Carbohydrate Interactions

Author(s): Sangho Won, Steven Hindmarsh, Matthew I. Gibson
Published in: ACS Macro Letters, Issue 7/2, 2018, Page(s) 178-183, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00891

Permeable Protein-Loaded Polymersome Cascade Nanoreactors by Polymerization-Induced Self-Assembly

Author(s): Lewis D. Blackman, Spyridon Varlas, Maria C. Arno, Alice Fayter, Matthew I. Gibson, Rachel K. O’Reilly
Published in: ACS Macro Letters, Issue 6/11, 2017, Page(s) 1263-1267, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00725

Comparison of photo- and thermally initiated polymerization-induced self-assembly: a lack of end group fidelity drives the formation of higher order morphologies

Author(s): Lewis D. Blackman, Kay E. B. Doncom, Matthew I. Gibson, Rachel K. O'Reilly
Published in: Polymer Chemistry, Issue 8/18, 2017, Page(s) 2860-2871, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/c7py00407a

Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility

Author(s): Lewis D. Blackman, Spyridon Varlas, Maria C. Arno, Zachary H. Houston, Nicholas L. Fletcher, Kristofer J. Thurecht, Muhammad Hasan, Matthew I. Gibson, Rachel K. O’Reilly
Published in: ACS Central Science, Issue 4/6, 2018, Page(s) 718-723, ISSN 2374-7943
Publisher: ACS
DOI: 10.1021/acscentsci.8b00168

Combining Biomimetic Block Copolymer Worms with an Ice-Inhibiting Polymer for the Solvent-Free Cryopreservation of Red Blood Cells

Author(s): Daniel E. Mitchell, Joseph R. Lovett, Steven P. Armes, Matthew I. Gibson
Published in: Angewandte Chemie International Edition, Issue 55/8, 2016, Page(s) 2801-2804, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201511454

Enhanced non-vitreous cryopreservation of immortalized and primary cells by ice-growth inhibiting polymers

Author(s): Robert C. Deller, Jeffrey E. Pessin, Manu Vatish, Daniel A. Mitchell, Matthew I. Gibson
Published in: Biomater. Sci., Issue 4/7, 2016, Page(s) 1079-1084, ISSN 2047-4830
Publisher: Royal Society of Chemistry
DOI: 10.1039/C6BM00129G

Influence of Block Copolymerization on the Antifreeze Protein Mimetic Ice Recrystallization Inhibition Activity of Poly(vinyl alcohol)

Author(s): Thomas R. Congdon, Rebecca Notman, Matthew I. Gibson
Published in: Biomacromolecules, Issue 17/9, 2016, Page(s) 3033-3039, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.6b00915

Co-operative transitions of responsive-polymer coated gold nanoparticles; precision tuning and direct evidence for co-operative aggregation

Author(s): Sangho Won, Daniel J. Phillips, Marc Walker, Matthew I. Gibson
Published in: J. Mater. Chem. B, Issue 4/34, 2016, Page(s) 5673-5682, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/C6TB01336H

Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

Author(s): Lucienne Otten, Elizabeth Fullam, Matthew I. Gibson
Published in: Mol. BioSyst., Issue 12/2, 2016, Page(s) 341-344, ISSN 1742-206X
Publisher: Royal Society of Chemistry
DOI: 10.1039/C5MB00720H

Latent Ice Recrystallization Inhibition Activity in Nonantifreeze Proteins: Ca 2+ -Activated Plant Lectins and Cation-Activated Antimicrobial Peptides

Author(s): Daniel E. Mitchell, Matthew I. Gibson
Published in: Biomacromolecules, Issue 16/10, 2015, Page(s) 3411-3416, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.5b01118

One-step grafting of polymers to graphene oxide

Author(s): Helen R. Thomas, Daniel J. Phillips, Neil R. Wilson, Matthew I. Gibson, Jonathan P. Rourke
Published in: Polym. Chem., Issue 6/48, 2015, Page(s) 8270-8274, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/C5PY01358E

Probing the Biomimetic Ice Nucleation Inhibition Activity of Poly(vinyl alcohol) and Comparison to Synthetic and Biological Polymers

Author(s): Thomas Congdon, Bethany T. Dean, James Kasperczak-Wright, Caroline I. Biggs, Rebecca Notman, Matthew I. Gibson
Published in: Biomacromolecules, Issue 16/9, 2015, Page(s) 2820-2826, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.5b00774

Glycan heterogeneity on gold nanoparticles increases lectin discrimination capacity in label-free multiplexed bioassays

Author(s): Lucienne Otten, Denise Vlachou, Sarah-Jane Richards, Matthew I. Gibson
Published in: The Analyst, Issue 141/14, 2016, Page(s) 4305-4312, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/C6AN00549G

Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles

Author(s): Laura E. Wilkins, Muhammad Hasan, Alice E. R. Fayter, Caroline Biggs, Marc Walker, Matthew I. Gibson
Published in: Polymer Chemistry, Issue 10/23, 2019, Page(s) 2986-2990, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8py01719k

Ice-recrystallization inhibiting polymers protect proteins against freeze-stress and enable glycerol-free cryostorage

Author(s): Daniel E. Mitchell, Alice E. R. Fayter, Robert C. Deller, Muhammad Hasan, Jose Gutierrez-Marcos, Matthew I. Gibson
Published in: Materials Horizons, Issue 6/2, 2019, Page(s) 364-368, ISSN 2051-6347
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8mh00727f

Photo-polymerisation and study of the ice recrystallisation inhibition of hydrophobically modified poly(vinyl pyrrolidone) co-polymers

Author(s): Christopher Stubbs, Thomas R Congdon, Matthew I. Gibson
Published in: European Polymer Journal, Issue 110, 2019, Page(s) 330-336, ISSN 0014-3057
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.eurpolymj.2018.11.047

Mimicking the Ice Recrystallization Activity of Biological Antifreezes. When is a New Polymer “Active”?

Author(s): Caroline I. Biggs, Christopher Stubbs, Ben Graham, Alice E. R. Fayter, Muhammad Hasan, Matthew I. Gibson
Published in: Macromolecular Bioscience, Issue Mater. Horiz., 2019,6, 364-368, 2019, Page(s) 1900082, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201900082

Optimization and Stability of Cell-Polymer Hybrids Obtained by ‘Clicking’ Synthetic Polymers to Metabolically-Labeled Cell Surface Glycans

Author(s): Ruben M. F. Tomas, Matthew I. Gibson
Published in: Biomacromolecules, 2019, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.9b00478

Engineering Cell Surfaces by Covalent Grafting of Synthetic Polymers to Metabolically-Labeled Glycans

Author(s): Ruben M. F. Tomás, Benjamin Martyn, Trisha L. Bailey, Matthew I. Gibson
Published in: ACS Macro Letters, Issue 7/11, 2018, Page(s) 1289-1294, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.8b00675

Ice Recrystallization Inhibiting Polymers Enable Glycerol-Free Cryopreservation of Microorganisms

Author(s): Muhammad Hasan, Alice E. R. Fayter, Matthew I. Gibson
Published in: Biomacromolecules, Issue 19/8, 2018, Page(s) 3371-3376, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.8b00660

Comparison of systematically functionalized heterogeneous and homogenous glycopolymers as toxin inhibitors

Author(s): Benjamin Martyn, Caroline I. Biggs, Matthew I. Gibson
Published in: Journal of Polymer Science Part A: Polymer Chemistry, Issue 57/1, 2018, Page(s) 40-47, ISSN 0887-624X
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/pola.29279

Sub-zero temperature mechanically stable low molecular weight hydrogels

Author(s): Alice E. R. Fayter, Matthew I. Gibson, Emily R. Draper
Published in: Journal of Materials Chemistry B, Issue 6/44, 2018, Page(s) 7274-7279, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8tb01668b

Multivalent Presentation of Ice Recrystallization Inhibiting Polymers on Nanoparticles Retains Activity

Author(s): Christopher Stubbs, Laura E. Wilkins, Alice E. R Fayter, Marc Walker, Matthew I. Gibson
Published in: Langmuir, Issue 35/23, 2018, Page(s) 7347-7353, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.8b01952

X-ray diffraction to probe the kinetics of ice recrystallization inhibition

Author(s): Alice Fayter, Steven Huband, Matthew I. Gibson
Published in: The Analyst, Issue 145/10, 2020, Page(s) 3666-3677, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9an02141h

Combinatorial Biomaterials Discovery Strategy to Identify New Macromolecular Cryoprotectants

Author(s): Christopher Stubbs, Kathryn A. Murray, Toru Ishibe, Robert T. Mathers, Matthew I. Gibson
Published in: ACS Macro Letters, Issue 9/2, 2020, Page(s) 290-294, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.0c00044

Polyampholytes as Emerging Macromolecular Cryoprotectants

Author(s): Christopher Stubbs, Trisha L. Bailey, Kathryn Murray, Matthew I. Gibson
Published in: Biomacromolecules, Issue 21/1, 2020, Page(s) 7-17, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.9b01053

Ice recrystallisation inhibiting polymer nano-objects via saline-tolerant polymerisation-induced self-assembly

Author(s): Panagiotis G. Georgiou, Ioanna Kontopoulou, Thomas R. Congdon, Matthew I. Gibson
Published in: Materials Horizons, Issue Mater. Horiz., 2020, Advance Article, 2020, ISSN 2051-6347
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0mh00354a

Post-thaw Culture and Measurement of Total Cell Recovery is Crucial in the Evaluation of New Macromolecular Cryoprotectants

Author(s): Kathryn A Murray, Matthew I. Gibson
Published in: Biomacromolecules, 2020, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.0c00591

Enhancement of Macromolecular Ice Recrystallization Inhibition Activity by Exploiting Depletion Forces

Author(s): Toru Ishibe, Thomas Congdon, Christopher Stubbs, Muhammad Hasan, Gabriele C. Sosso, Matthew I. Gibson
Published in: ACS Macro Letters, Issue 8/8, 2019, Page(s) 1063-1067, ISSN 2161-1653
Publisher: American Chemical Society
DOI: 10.1021/acsmacrolett.9b00386

Searching for OpenAIRE data...

Publications

Share this page

Download