Antifreeze GlycoProtein Mimetic Polymers

Publicaciones

High-Throughput Tertiary Amine Deoxygenated Photopolymerizations for Synthesizing Polymer Libraries

Autores: Christopher Stubbs, Thomas Congdon, Jessica Davis, Daniel Lester, Sarah-Jane Richards, Matthew I. Gibson
Publicado en: Macromolecules, Edición 52/20, 2019, Página(s) 7603-7612, ISSN 0024-9297
Editor: American Chemical Society
DOI: 10.1021/acs.macromol.9b01714

Synthetically Scalable Poly(ampholyte) Which Dramatically Enhances Cellular Cryopreservation

Autores: Trisha L. Bailey, Christopher Stubbs, Kathryn Murray, Ruben M. F. Tomás, Lucienne Otten, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 20/8, 2019, Página(s) 3104-3114, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.9b00681

Low DMSO Cryopreservation of Stem Cells Enabled by Macromolecular Cryoprotectants

Autores: Kathryn A. Murray, Ruben M. F. Tomás, Matthew I. Gibson
Publicado en: ACS Applied Bio Materials, Edición 3/9, 2020, Página(s) 5627-5632, ISSN 2576-6422
Editor: ACS
DOI: 10.1021/acsabm.0c00638

Double-Modified Glycopolymers from Thiolactones to Modulate Lectin Selectivity and Affinity

Autores: Laura E. Wilkins, Nezha Badi, Filip Du Prez, Matthew I. Gibson
Publicado en: ACS Macro Letters, Edición 7/12, 2018, Página(s) 1498-1502, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.8b00825

Extracellular Antifreeze Protein Significantly Enhances the Cryopreservation of Cell Monolayers

Autores: Ruben M. F. Tomás, Trisha L. Bailey, Muhammad Hasan, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 20/10, 2019, Página(s) 3864-3872, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.9b00951

Photochemical “In-Air” Combinatorial Discovery of Antimicrobial Co-polymers

Autores: Sarah-Jane Richards, Adam Jones, Ruben M. F. Tomás, Matthew I. Gibson
Publicado en: Chemistry - A European Journal, Edición 24/52, 2018, Página(s) 13758-13761, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.201802594

Probing the causes of thermal hysteresis using tunable N agg micelles with linear and brush-like thermoresponsive coronas

Autores: L. D. Blackman, M. I. Gibson, R. K. O'Reilly
Publicado en: Polymer Chemistry, Edición 8/1, 2017, Página(s) 233-244, ISSN 1759-9954
Editor: Royal Society of Chemistry
DOI: 10.1039/C6PY01191H

Antifreeze Protein Mimetic Metallohelices with Potent Ice Recrystallization Inhibition Activity

Autores: Daniel E. Mitchell, Guy Clarkson, David J. Fox, Rebecca A. Vipond, Peter Scott, Matthew I. Gibson
Publicado en: Journal of the American Chemical Society, Edición 139/29, 2017, Página(s) 9835-9838, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.7b05822

Evaluation of the Antimicrobial Activity of Cationic Polymers against Mycobacteria: Toward Antitubercular Macromolecules

Autores: Daniel J. Phillips, James Harrison, Sarah-Jane Richards, Daniel E. Mitchell, Esther Tichauer, Alasdair T. M. Hubbard, Collette Guy, Ian Hands-Portman, Elizabeth Fullam, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 18/5, 2017, Página(s) 1592-1599, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.7b00210

Identification of the anti-mycobacterial functional properties of piperidinol derivatives

Autores: Collette S Guy, Esther Tichauer, Gemma L Kay, Daniel J Phillips, Trisha L Bailey, James Harrison, Christopher M Furze, Andrew D Millard, Matthew I Gibson, Mark J Pallen, Elizabeth Fullam
Publicado en: British Journal of Pharmacology, Edición 174/14, 2017, Página(s) 2183-2193, ISSN 0007-1188
Editor: Wiley-Blackwell
DOI: 10.1111/bph.13744

Regioregular Alternating Polyampholytes Have Enhanced Biomimetic Ice Recrystallization Activity Compared to Random Copolymers and the Role of Side Chain versus Main Chain Hydrophobicity

Autores: Christopher Stubbs, Julia Lipecki, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 18/1, 2016, Página(s) 295-302, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.6b01691

Externally controllable glycan presentation on nanoparticle surfaces to modulate lectin recognition

Autores: Sangho Won, Sarah-Jane Richards, Marc Walker, Matthew I. Gibson
Publicado en: Nanoscale Horizons, Edición 2/2, 2017, Página(s) 106-109, ISSN 2055-6756
Editor: Royal Society of Chemistry
DOI: 10.1039/c6nh00202a

“Grafting to” of RAFTed Responsive Polymers to Glass Substrates by Thiol–Ene and Critical Comparison to Thiol–Gold Coupling

Autores: Caroline I. Biggs, Marc Walker, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 17/8, 2016, Página(s) 2626-2633, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.6b00662

Activation of ice recrystallization inhibition activity of poly(vinyl alcohol) using a supramolecular trigger

Autores: Daniel J. Phillips, Thomas R. Congdon, Matthew I. Gibson
Publicado en: Polymer Chemistry, Edición 7/9, 2016, Página(s) 1701-1704, ISSN 1759-9954
Editor: Royal Society of Chemistry
DOI: 10.1039/c5py01948f

Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms

Autores: Sarah-Jane Richards, Klea Isufi, Laura E. Wilkins, Julia Lipecki, Elizabeth Fullam, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 19/1, 2017, Página(s) 256-264, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.7b01561

Impact of sequential surface-modification of graphene oxide on ice nucleation

Autores: Caroline I. Biggs, Christopher Packer, Steven Hindmarsh, Marc Walker, Neil R. Wilson, Jonathan P. Rourke, Matthew I. Gibson
Publicado en: Physical Chemistry Chemical Physics, Edición 19/33, 2017, Página(s) 21929-21932, ISSN 1463-9076
Editor: Royal Society of Chemistry
DOI: 10.1039/C7CP03219F

Ultralow Dispersity Poly(vinyl alcohol) Reveals Significant Dispersity Effects on Ice Recrystallization Inhibition Activity

Autores: Nicholas S. Vail, Christopher Stubbs, Caroline I. Biggs, Matthew I. Gibson
Publicado en: ACS Macro Letters, Edición 6/9, 2017, Página(s) 1001-1004, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00595

Polyproline as a Minimal Antifreeze Protein Mimic That Enhances the Cryopreservation of Cell Monolayers

Autores: Ben Graham, Trisha L. Bailey, Joseph R. J. Healey, Moreno Marcellini, Sylvain Deville, Matthew I. Gibson
Publicado en: Angewandte Chemie International Edition, Edición 56/50, 2017, Página(s) 15941-15944, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201706703

Structure-activity relationship of the exopolysaccharide from a psychrophilic bacterium: A strategy for cryoprotection

Autores: Angela Casillo, Ermenegilda Parrilli, Filomena Sannino, Daniel E. Mitchell, Matthew I. Gibson, Gennaro Marino, Rosa Lanzetta, Michelangelo Parrilli, Sandro Cosconati, Ettore Novellino, Antonio Randazzo, Maria L. Tutino, M. Michela Corsaro
Publicado en: Carbohydrate Polymers, Edición 156, 2017, Página(s) 364-371, ISSN 0144-8617
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.carbpol.2016.09.037

Polymer mimics of biomacromolecular antifreezes

Autores: Caroline I. Biggs, Trisha L. Bailey, Ben Graham, Christopher Stubbs, Alice Fayter, Matthew I. Gibson
Publicado en: Nature Communications, Edición 8/1, 2017, Página(s) 1546, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-017-01421-7

Synthesis of Degradable Poly(vinyl alcohol) by Radical Ring-Opening Copolymerization and Ice Recrystallization Inhibition Activity

Autores: Guillaume Hedir, Christopher Stubbs, Phillip Aston, Andrew P. Dove, Matthew I. Gibson
Publicado en: ACS Macro Letters, Edición 6/12, 2017, Página(s) 1404-1408, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00905

Facially Amphipathic Glycopolymers Inhibit Ice Recrystallization

Autores: Ben Graham, Alice E. R. Fayter, Judith E. Houston, Rachel C. Evans, Matthew I. Gibson
Publicado en: Journal of the American Chemical Society, Edición 140/17, 2018, Página(s) 5682-5685, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.8b02066

Triggerable Multivalent Glyconanoparticles for Probing Carbohydrate–Carbohydrate Interactions

Autores: Sangho Won, Steven Hindmarsh, Matthew I. Gibson
Publicado en: ACS Macro Letters, Edición 7/2, 2018, Página(s) 178-183, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00891

Permeable Protein-Loaded Polymersome Cascade Nanoreactors by Polymerization-Induced Self-Assembly

Autores: Lewis D. Blackman, Spyridon Varlas, Maria C. Arno, Alice Fayter, Matthew I. Gibson, Rachel K. O’Reilly
Publicado en: ACS Macro Letters, Edición 6/11, 2017, Página(s) 1263-1267, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.7b00725

Comparison of photo- and thermally initiated polymerization-induced self-assembly: a lack of end group fidelity drives the formation of higher order morphologies

Autores: Lewis D. Blackman, Kay E. B. Doncom, Matthew I. Gibson, Rachel K. O'Reilly
Publicado en: Polymer Chemistry, Edición 8/18, 2017, Página(s) 2860-2871, ISSN 1759-9954
Editor: Royal Society of Chemistry
DOI: 10.1039/c7py00407a

Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility

Autores: Lewis D. Blackman, Spyridon Varlas, Maria C. Arno, Zachary H. Houston, Nicholas L. Fletcher, Kristofer J. Thurecht, Muhammad Hasan, Matthew I. Gibson, Rachel K. O’Reilly
Publicado en: ACS Central Science, Edición 4/6, 2018, Página(s) 718-723, ISSN 2374-7943
Editor: ACS
DOI: 10.1021/acscentsci.8b00168

Combining Biomimetic Block Copolymer Worms with an Ice-Inhibiting Polymer for the Solvent-Free Cryopreservation of Red Blood Cells

Autores: Daniel E. Mitchell, Joseph R. Lovett, Steven P. Armes, Matthew I. Gibson
Publicado en: Angewandte Chemie International Edition, Edición 55/8, 2016, Página(s) 2801-2804, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201511454

Enhanced non-vitreous cryopreservation of immortalized and primary cells by ice-growth inhibiting polymers

Autores: Robert C. Deller, Jeffrey E. Pessin, Manu Vatish, Daniel A. Mitchell, Matthew I. Gibson
Publicado en: Biomater. Sci., Edición 4/7, 2016, Página(s) 1079-1084, ISSN 2047-4830
Editor: Royal Society of Chemistry
DOI: 10.1039/C6BM00129G

Influence of Block Copolymerization on the Antifreeze Protein Mimetic Ice Recrystallization Inhibition Activity of Poly(vinyl alcohol)

Autores: Thomas R. Congdon, Rebecca Notman, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 17/9, 2016, Página(s) 3033-3039, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.6b00915

Co-operative transitions of responsive-polymer coated gold nanoparticles; precision tuning and direct evidence for co-operative aggregation

Autores: Sangho Won, Daniel J. Phillips, Marc Walker, Matthew I. Gibson
Publicado en: J. Mater. Chem. B, Edición 4/34, 2016, Página(s) 5673-5682, ISSN 2050-7518
Editor: Royal Society of Chemistry
DOI: 10.1039/C6TB01336H

Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

Autores: Lucienne Otten, Elizabeth Fullam, Matthew I. Gibson
Publicado en: Mol. BioSyst., Edición 12/2, 2016, Página(s) 341-344, ISSN 1742-206X
Editor: Royal Society of Chemistry
DOI: 10.1039/C5MB00720H

Latent Ice Recrystallization Inhibition Activity in Nonantifreeze Proteins: Ca 2+ -Activated Plant Lectins and Cation-Activated Antimicrobial Peptides

Autores: Daniel E. Mitchell, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 16/10, 2015, Página(s) 3411-3416, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.5b01118

One-step grafting of polymers to graphene oxide

Autores: Helen R. Thomas, Daniel J. Phillips, Neil R. Wilson, Matthew I. Gibson, Jonathan P. Rourke
Publicado en: Polym. Chem., Edición 6/48, 2015, Página(s) 8270-8274, ISSN 1759-9954
Editor: Royal Society of Chemistry
DOI: 10.1039/C5PY01358E

Probing the Biomimetic Ice Nucleation Inhibition Activity of Poly(vinyl alcohol) and Comparison to Synthetic and Biological Polymers

Autores: Thomas Congdon, Bethany T. Dean, James Kasperczak-Wright, Caroline I. Biggs, Rebecca Notman, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 16/9, 2015, Página(s) 2820-2826, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.5b00774

Glycan heterogeneity on gold nanoparticles increases lectin discrimination capacity in label-free multiplexed bioassays

Autores: Lucienne Otten, Denise Vlachou, Sarah-Jane Richards, Matthew I. Gibson
Publicado en: The Analyst, Edición 141/14, 2016, Página(s) 4305-4312, ISSN 0003-2654
Editor: Royal Society of Chemistry
DOI: 10.1039/C6AN00549G

Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles

Autores: Laura E. Wilkins, Muhammad Hasan, Alice E. R. Fayter, Caroline Biggs, Marc Walker, Matthew I. Gibson
Publicado en: Polymer Chemistry, Edición 10/23, 2019, Página(s) 2986-2990, ISSN 1759-9954
Editor: Royal Society of Chemistry
DOI: 10.1039/c8py01719k

Ice-recrystallization inhibiting polymers protect proteins against freeze-stress and enable glycerol-free cryostorage

Autores: Daniel E. Mitchell, Alice E. R. Fayter, Robert C. Deller, Muhammad Hasan, Jose Gutierrez-Marcos, Matthew I. Gibson
Publicado en: Materials Horizons, Edición 6/2, 2019, Página(s) 364-368, ISSN 2051-6347
Editor: Royal Society of Chemistry
DOI: 10.1039/c8mh00727f

Photo-polymerisation and study of the ice recrystallisation inhibition of hydrophobically modified poly(vinyl pyrrolidone) co-polymers

Autores: Christopher Stubbs, Thomas R Congdon, Matthew I. Gibson
Publicado en: European Polymer Journal, Edición 110, 2019, Página(s) 330-336, ISSN 0014-3057
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.eurpolymj.2018.11.047

Mimicking the Ice Recrystallization Activity of Biological Antifreezes. When is a New Polymer “Active”?

Autores: Caroline I. Biggs, Christopher Stubbs, Ben Graham, Alice E. R. Fayter, Muhammad Hasan, Matthew I. Gibson
Publicado en: Macromolecular Bioscience, Edición Mater. Horiz., 2019,6, 364-368, 2019, Página(s) 1900082, ISSN 1616-5187
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.201900082

Optimization and Stability of Cell-Polymer Hybrids Obtained by ‘Clicking’ Synthetic Polymers to Metabolically-Labeled Cell Surface Glycans

Autores: Ruben M. F. Tomas, Matthew I. Gibson
Publicado en: Biomacromolecules, 2019, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.9b00478

Engineering Cell Surfaces by Covalent Grafting of Synthetic Polymers to Metabolically-Labeled Glycans

Autores: Ruben M. F. Tomás, Benjamin Martyn, Trisha L. Bailey, Matthew I. Gibson
Publicado en: ACS Macro Letters, Edición 7/11, 2018, Página(s) 1289-1294, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.8b00675

Ice Recrystallization Inhibiting Polymers Enable Glycerol-Free Cryopreservation of Microorganisms

Autores: Muhammad Hasan, Alice E. R. Fayter, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 19/8, 2018, Página(s) 3371-3376, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.8b00660

Comparison of systematically functionalized heterogeneous and homogenous glycopolymers as toxin inhibitors

Autores: Benjamin Martyn, Caroline I. Biggs, Matthew I. Gibson
Publicado en: Journal of Polymer Science Part A: Polymer Chemistry, Edición 57/1, 2018, Página(s) 40-47, ISSN 0887-624X
Editor: John Wiley & Sons Inc.
DOI: 10.1002/pola.29279

Sub-zero temperature mechanically stable low molecular weight hydrogels

Autores: Alice E. R. Fayter, Matthew I. Gibson, Emily R. Draper
Publicado en: Journal of Materials Chemistry B, Edición 6/44, 2018, Página(s) 7274-7279, ISSN 2050-7518
Editor: Royal Society of Chemistry
DOI: 10.1039/c8tb01668b

Multivalent Presentation of Ice Recrystallization Inhibiting Polymers on Nanoparticles Retains Activity

Autores: Christopher Stubbs, Laura E. Wilkins, Alice E. R Fayter, Marc Walker, Matthew I. Gibson
Publicado en: Langmuir, Edición 35/23, 2018, Página(s) 7347-7353, ISSN 0743-7463
Editor: American Chemical Society
DOI: 10.1021/acs.langmuir.8b01952

X-ray diffraction to probe the kinetics of ice recrystallization inhibition

Autores: Alice Fayter, Steven Huband, Matthew I. Gibson
Publicado en: The Analyst, Edición 145/10, 2020, Página(s) 3666-3677, ISSN 0003-2654
Editor: Royal Society of Chemistry
DOI: 10.1039/c9an02141h

Combinatorial Biomaterials Discovery Strategy to Identify New Macromolecular Cryoprotectants

Autores: Christopher Stubbs, Kathryn A. Murray, Toru Ishibe, Robert T. Mathers, Matthew I. Gibson
Publicado en: ACS Macro Letters, Edición 9/2, 2020, Página(s) 290-294, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.0c00044

Polyampholytes as Emerging Macromolecular Cryoprotectants

Autores: Christopher Stubbs, Trisha L. Bailey, Kathryn Murray, Matthew I. Gibson
Publicado en: Biomacromolecules, Edición 21/1, 2020, Página(s) 7-17, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.9b01053

Ice recrystallisation inhibiting polymer nano-objects via saline-tolerant polymerisation-induced self-assembly

Autores: Panagiotis G. Georgiou, Ioanna Kontopoulou, Thomas R. Congdon, Matthew I. Gibson
Publicado en: Materials Horizons, Edición Mater. Horiz., 2020, Advance Article, 2020, ISSN 2051-6347
Editor: Royal Society of Chemistry
DOI: 10.1039/d0mh00354a

Post-thaw Culture and Measurement of Total Cell Recovery is Crucial in the Evaluation of New Macromolecular Cryoprotectants

Autores: Kathryn A Murray, Matthew I. Gibson
Publicado en: Biomacromolecules, 2020, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.0c00591

Enhancement of Macromolecular Ice Recrystallization Inhibition Activity by Exploiting Depletion Forces

Autores: Toru Ishibe, Thomas Congdon, Christopher Stubbs, Muhammad Hasan, Gabriele C. Sosso, Matthew I. Gibson
Publicado en: ACS Macro Letters, Edición 8/8, 2019, Página(s) 1063-1067, ISSN 2161-1653
Editor: American Chemical Society
DOI: 10.1021/acsmacrolett.9b00386

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