Imaging Brain Circuits to Decode Brain Computations: Multimodal Multiscale Imaging of Cortical Microcircuits to Model Predictive Coding in Human Vision

Project Information

MULTICONNECT

Grant agreement ID: 639938

DOI 10.3030/639938

Project closed

EC signature date 11 May 2015

Start date 1 June 2015

End date 30 November 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

UNIVERSITEIT MAASTRICHT
Netherlands

Publications

Other (3)

Monte Carlo Simulation of Diffusion MRI in geometries constructed from two-photon microscopy of cortical gray matter

Author(s): Alard Roebroeck; Nima Gilani; Anna Schueth; Sven Hildebrand
Published in: Issue 2, 2019
Publisher: bioRxiv
DOI: 10.1101/626945

MESMERISED: Super-accelerated 7 T STEAM imaging for quantitative multi-contrast and diffusion MRI

Author(s): F.J. Fritz, B.A. Poser, A. Roebroeck
Published in: 2020
Publisher: bioRxiv
DOI: 10.1101/2020.05.15.098269

Fast quantification of uncertainty in non-linear diffusion MRI models for artifact detection and more power in group studies

Author(s): Robbert L. Harms; Sanne Schoenmakers; Alard J. Roebroeck; Francisco J. Fritz
Published in: Issue 1, 2019
Publisher: bioRxiv
DOI: 10.1101/651547

Peer reviewed articles (15)

hFRUIT: An optimized agent for optical clearing of DiI-stained adult human brain tissue

Author(s): Sven Hildebrand, Anna Schueth, Klaus von Wangenheim, Christian Mattheyer, Francesco Pampaloni, Hansjürgen Bratzke, Alard F. Roebroeck, Ralf A. W. Galuske
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-66999-3

Compressed Sensing Diffusion Spectrum Imaging for Accelerated Diffusion Microstructure MRI in Long-Term Population Imaging

Author(s): Alexandra Tobisch, Rüdiger Stirnberg, Robbert L. Harms, Thomas Schultz, Alard Roebroeck, Monique M. B. Breteler, Tony Stöcker
Published in: Frontiers in Neuroscience, Issue 12, 2018, ISSN 1662-453X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnins.2018.00650

Robust and fast nonlinear optimization of diffusion MRI microstructure models

Author(s): R.L. Harms, F.J. Fritz, A. Tobisch, R. Goebel, A. Roebroeck
Published in: NeuroImage, Issue 155, 2017, Page(s) 82-96, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2017.04.064

Determining Excitatory and Inhibitory Neuronal Activity from Multimodal fMRI Data Using a Generative Hemodynamic Model

Author(s): Martin Havlicek, Dimo Ivanov, Alard Roebroeck, Kamil Uludağ
Published in: Frontiers in Neuroscience, Issue 11, 2017, ISSN 1662-453X
Publisher: Frontiers
DOI: 10.3389/fnins.2017.00616

High resolution anatomical and quantitative MRI of the entire human occipital lobe ex vivo at 9.4 T

Author(s): S. Sengupta, F.J. Fritz, R.L. Harms, S. Hildebrand, D.H.Y. Tse, B.A. Poser, R. Goebel, A. Roebroeck
Published in: NeuroImage, 2017, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2017.03.039

On the importance of modeling fMRI transients when estimating effective connectivity: A dynamic causal modeling study using ASL data

Author(s): Martin Havlicek, Alard Roebroeck, Karl J. Friston, Anna Gardumi, Dimo Ivanov, Kamil Uludag
Published in: NeuroImage, Issue 155, 2017, Page(s) 217-233, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2017.03.017

T1 relaxometry of crossing fibres in the human brain

Author(s): Silvia De Santis, Yaniv Assaf, Ben Jeurissen, Derek K Jones, Alard Roebroeck
Published in: NeuroImage, Issue 141, 2016, Page(s) 133-142, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2016.07.037

A Specialized Multi-Transmit Head Coil for High Resolution fMRI of the Human Visual Cortex at 7T

Author(s): Shubharthi Sengupta, Alard Roebroeck, Valentin G. Kemper, Benedikt A. Poser, Jan Zimmermann, Rainer Goebel, Gregor Adriany
Published in: PLOS ONE, Issue 11/12, 2016, Page(s) e0165418, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0165418

Ultra-High Field MRI Post Mortem Structural Connectivity of the Human Subthalamic Nucleus, Substantia Nigra, and Globus Pallidus

Author(s): Birgit R. Plantinga, Alard Roebroeck, Valentin G. Kemper, Kâmil Uludağ, Maartje Melse, Jürgen Mai, Mark L. Kuijf, Andreas Herrler, Ali Jahanshahi, Bart M. ter Haar Romeny, Yasin Temel
Published in: Frontiers in Neuroanatomy, Issue 10, 2016, ISSN 1662-5129
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnana.2016.00066

Including diffusion time dependence in the extra-axonal space improves in vivo estimates of axonal diameter and density in human white matter

Author(s): Silvia De Santis, Derek K. Jones, Alard Roebroeck
Published in: NeuroImage, Issue 130, 2016, Page(s) 91-103, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2016.01.047

Automatic Segmentation of Human Cortical Layer-Complexes and Architectural Areas Using Ex vivo Diffusion MRI and Its Validation

Author(s): Matteo Bastiani, Ana-Maria Oros-Peusquens, Arne Seehaus, Daniel Brenner, Klaus Möllenhoff, Avdo Celik, Jörg Felder, Hansjürgen Bratzke, Nadim J. Shah, Ralf Galuske, Rainer Goebel, Alard Roebroeck
Published in: Frontiers in Neuroscience, Issue 10, 2016, ISSN 1662-453X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnins.2016.00487

Robust and Fast Markov Chain Monte Carlo Sampling of Diffusion MRI Microstructure Models

Author(s): Robbert L. Harms, Alard Roebroeck
Published in: Frontiers in Neuroinformatics, Issue 12, 2018, ISSN 1662-5196
Publisher: Frontiers Research Foundation
DOI: 10.3389/fninf.2018.00097

Ultra-high resolution and multi-shell diffusion MRI of intact ex vivo human brains using kT-dSTEAM at 9.4T

Author(s): F.J. Fritz, S. Sengupta, R.L. Harms, D.H. Tse, B.A. Poser, A. Roebroeck
Published in: NeuroImage, Issue 202, 2019, Page(s) 116087, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2019.116087

Ex vivo diffusion MRI of the human brain: Technical challenges and recent advances

Author(s): Alard Roebroeck, Karla L. Miller, Manisha Aggarwal
Published in: NMR in Biomedicine, Issue 32/4, 2018, Page(s) e3941, ISSN 0952-3480
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/nbm.3941

Curvilinear locus coeruleus functional connectivity trajectories over the adult lifespan: a 7T MRI study

Author(s): Heidi I.L. Jacobs, Lisa Müller-Ehrenberg, Nikos Priovoulos, Alard Roebroeck
Published in: Neurobiology of Aging, Issue 69, 2018, Page(s) 167-176, ISSN 0197-4580
Publisher: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2018.05.021

Non-peer reviewed articles (2)

Scalable cytoarchitectonic characterization of large intact human neocortex samples

Author(s): Roebroeck, Alard; Galuske, Ralf; Herrler, Andreas; Schueth, Anna; Hildebrand, Sven
Published in: Nature Scientific Reports, Issue 1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1101/274985

The mesoSPIM initiative: open-source light-sheet mesoscopes for imaging in cleared tissue

Author(s): Fabian F. Voigt, Daniel Kirschenbaum, Evgenia Platonova, Stéphane Pagès, Robert A. A. Campbell, Rahel Kästli, Martina Schaettin, Ladan Egolf, Alexander van der Bourg, Philipp Bethge, Karen Haenraets, Noémie Frézel, Thomas Topilko, Paola Perin, Daniel Hillier, Sven Hildebrand, Anna Schueth, Alard Roebroeck, Botond Roska, Esther Stoeckli, Roberto Pizzala, Nicolas Renier, Hanns Ulrich Zeilhofer,
Published in: Nature Methods, 2020, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1101/577122