Resultado final Documents, reports (4) Draft Periodic Report Compulsory deliverable Mid-Term Review meeting Compulsory deliverable Progress Report Compulsory deliverable Ethics Compulsory deliverable Websites, patent fillings, videos etc. (2) ONCORNET website ONCORNET website built and online wwwoncorneteu 2 Output Abstracts for international conferences and publications submitted Other (2) Open meetings organized Kick-off organised in conjunction with AIMMS-GPCR symposium (7) Final meeting organised Supervisory board of Network Compulsory deliverable Publicaciones Book chapters (3) Molecular Pharmacology of Chemokine Receptors Autores: Raymond H. de Wit, Sabrina M. de Munnik, Rob Leurs, Henry F. Vischer and Martine J. Smit Publicado en: Methods in Enzymology, editor: Tracy M. Handel, Issue 570, 2016, Page(s) 457-515, ISBN 978-0-12-802171-2 Editor: Academic Press DOI: 10.1016/bs.mie.2015.12.002 Time-Resolved FRET-Based Assays to Characterize G Protein-Coupled Receptor Hetero-oligomer Pharmacology Autores: Joyce Heuninck, Candide Hounsou, Elodie Dupuis, Eric Trinquet, Bernard Mouillac, Jean-Philippe Pin, Dominique Bonnet, Thierry Durroux Publicado en: G Protein-Coupled Receptor Signaling - Methods and Protocols, Issue 1947, 2019, Page(s) 151-168, ISBN 978-1-4939-9120-4 Editor: Springer New York DOI: 10.1007/978-1-4939-9121-1_8 Fluorescent-Based Strategies to Investigate G Protein-Coupled Receptors: Evolution of the Techniques to a Better Understanding Autores: Orestis Faklaris, Joyce Heuninck, Amandine Falco, Elise Goyet, Jurriaan M. Zwier, Jean-Philippe Pin, Bernard Mouillac, Julie Perroy, Thierry Durroux Publicado en: Topics in Medicinal Chemistry, 2017 Editor: Springer Berlin Heidelberg DOI: 10.1007/7355_2017_2 Peer reviewed articles (15) Atypical chemokine receptor 3 (ACKR3): a comprehensive overview of its expression and potential roles in the immune system. Autores: Joyce Koenen, Francoise Bachelerie, Karl Balabanian, Geraldine Schlecht-Louf, Carmen Gallego Publicado en: Molecular Pharmacology, 2019, Page(s) mol.118.115329, ISSN 0026-895X Editor: American Society for Pharmacology and Experimental Therapeutics DOI: 10.1124/mol.118.115329 Nanobodies: New avenues for imaging, stabilizing and modulating GPCRs Autores: Timo W.M. De Groof, Vladimir Bobkov, Raimond Heukers, Martine J. Smit Publicado en: Molecular and Cellular Endocrinology, Issue 484, 2019, Page(s) 15-24, ISSN 0303-7207 Editor: Elsevier BV DOI: 10.1016/j.mce.2019.01.021 CXCR4/ACKR3 phosphorylation and recruitment of interacting proteins: key mechanisms regulating their functional status Autores: Amos Fumagalli, Aurelien Zarca, Maria Neves, Birgit Caspar, Stephen J Hill, Federico Mayor, Martine J Smit, Philippe Marin Publicado en: Molecular Pharmacology, 2019, Page(s) mol.118.115360, ISSN 0026-895X Editor: American Society for Pharmacology and Experimental Therapeutics DOI: 10.1124/mol.118.115360 The role of ACKR3 in breast, lung and brain cancer. Autores: Maria Neves, Amos Fumagalli, Jelle van den Bor, Philippe Marin, Martine J Smit, Federico Mayor Publicado en: Molecular Pharmacology, 2019, Page(s) mol.118.115279, ISSN 0026-895X Editor: American Society for Pharmacology and Experimental Therapeutics DOI: 10.1124/mol.118.115279 Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists Autores: I. Adlere, S. Sun, A. Zarca, L. Roumen, M. Gozelle, C. Perpiñá Viciano, B. Caspar, M. Arimont, J.P. Bebelman, S.J. Briddon, C. Hoffmann, S.J. Hill, M.J. Smit, H.F. Vischer, M. Wijtmans, C. de Graaf, I.J.P. de Esch, R. Leurs Publicado en: European Journal of Medicinal Chemistry, Issue 162, 2019, Page(s) 631-649, ISSN 0223-5234 Editor: Elsevier BV DOI: 10.1016/j.ejmech.2018.10.060 CXCR4-targeting nanobodies differentially inhibit CXCR4 function and HIV entry Autores: Anneleen Van Hout, Alex Klarenbeek, Vladimir Bobkov, Jordi Doijen, Marta Arimont, Chunxia Zhao, Raimond Heukers, Rebecca Rimkunas, Chris de Graaf, Theo Verrips, Bas van der Woning, Hans de Haard, Joseph B. Rucker, Kurt Vermeire, Tracy Handel, Tom Van Loy, Martine J. Smit, Dominique Schols Publicado en: Biochemical Pharmacology, Issue 158, 2018, Page(s) 402-412, ISSN 0006-2952 Editor: Elsevier BV DOI: 10.1016/j.bcp.2018.10.015 G protein-coupled receptor kinases (GRKs) in tumorigenesis and cancer progression: GPCR regulators and signaling hubs Autores: Laura Nogués, Julia Palacios-García, Clara Reglero, Verónica Rivas, María Neves, Catalina Ribas, Petronila Penela, Federico Mayor Publicado en: Seminars in Cancer Biology, Issue 48, 2018, Page(s) 78-90, ISSN 1044-579X Editor: Academic Press DOI: 10.1016/j.semcancer.2017.04.013 Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions Autores: Vladimir Bobkov, Aurelien M. Zarca, Anneleen Van Hout, Marta Arimont, Jordi Doijen, Magdalena Bialkowska, Elisa Toffoli, Alex Klarenbeek, Bas van der Woning, Hans J. van der Vliet, Tom Van Loy, Hans de Haard, Dominique Schols, Raimond Heukers, Martine J. Smit Publicado en: Biochemical Pharmacology, Issue 158, 2018, Page(s) 413-424, ISSN 0006-2952 Editor: Elsevier BV DOI: 10.1016/j.bcp.2018.10.014 G-Protein–Coupled Receptor Kinase 2 as a Potential Modulator of the Hallmarks of Cancer Autores: Laura Nogués, Clara Reglero, Verónica Rivas, María Neves, Petronila Penela, Federico Mayor Publicado en: Molecular Pharmacology, Issue 91/3, 2017, Page(s) 220-228, ISSN 0026-895X Editor: American Society for Pharmacology and Experimental Therapeutics DOI: 10.1124/mol.116.107185 DNA immunization combined with scFv phage display identifies antagonistic GCGR specific antibodies and reveals new epitopes on the small extracellular loops Autores: Bas van der Woning, Gitte De Boeck, Christophe Blanchetot, Vladimir Bobkov, Alex Klarenbeek, Michael Saunders, Magali Waelbroeck, Toon Laeremans, Jan Steyaert, Anna Hultberg, Hans De Haard Publicado en: mAbs, Issue 8/6, 2016, Page(s) 1126-1135, ISSN 1942-0870 Editor: Landes Bioscience DOI: 10.1080/19420862.2016.1189050 CXCR4-Specific Nanobodies as Potential Therapeutics for WHIM syndrome Autores: Raymond H. de Wit, Raimond Heukers, Hendrik J. Brink, Angela Arsova, David Maussang, Pasquale Cutolo, Beatrijs Strubbe, Henry F. Vischer, Françoise Bachelerie, Martine J. Smit Publicado en: Journal of Pharmacology and Experimental Therapeutics, Issue 363/1, 2017, Page(s) 35-44, ISSN 0022-3565 Editor: American Society for Pharmacology and Experimental Therapeutics DOI: 10.1124/jpet.117.242735 G Protein-coupled Receptor Kinase 2 (GRK2) Promotes Breast Tumorigenesis Through a HDAC6-Pin1 Axis Autores: Laura Nogués, Clara Reglero, Verónica Rivas, Alicia Salcedo, Vanesa Lafarga, Maria Neves, Paula Ramos, Marta Mendiola, Alberto Berjón, Kostas Stamatakis, Xiao Zhen Zhou, Kun Ping Lu, David Hardisson, Federico Mayor, Petronila Penela Publicado en: EBioMedicine, Issue 13, 2016, Page(s) 132-145, ISSN 2352-3964 Editor: Elsevier BV DOI: 10.1016/j.ebiom.2016.09.030 Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats Autores: Beatrice Oehler, Milad Mohammadi, Cristina Perpina Viciano, Dagmar Hackel, Carsten Hoffmann, Alexander Brack, Heike L. Rittner Publicado en: Frontiers in Molecular Neuroscience, Issue 10, 2017, ISSN 1662-5099 Editor: Frontiers Research Foundation DOI: 10.3389/fnmol.2017.00242 Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement Autores: Nikaïa Smith, Nicolas Pietrancosta, Sophia Davidson, Jacques Dutrieux, Lise Chauveau, Pasquale Cutolo, Michel Dy, Daniel Scott-Algara, Bénédicte Manoury, Onofrio Zirafi, Isabelle McCort-Tranchepain, Thierry Durroux, Françoise Bachelerie, Olivier Schwartz, Jan Münch, Andreas Wack, Sébastien Nisole, Jean-Philippe Herbeuval Publicado en: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723 Editor: Nature Publishing Group DOI: 10.1038/ncomms14253 Structural Analysis of Chemokine Receptor–Ligand Interactions Autores: Marta Arimont, Shan-Liang Sun, Rob Leurs, Martine Smit, Iwan J. P. de Esch, Chris de Graaf Publicado en: Journal of Medicinal Chemistry, Issue 60/12, 2017, Page(s) 4735-4779, ISSN 0022-2623 Editor: American Chemical Society DOI: 10.1021/acs.jmedchem.6b01309 Buscando datos de OpenAIRE... Se ha producido un error en la búsqueda de datos de OpenAIRE No hay resultados disponibles
