MUltiSectoral Integrative approaches to CArdiac care

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Publications

Tailoring cardiac environment in microphysiological systems: an outlook on current and perspective heart-on-chip platforms

Author(s): Giovanni Stefano Ugolini, Roberta Visone, Daniela Cruz-Moreira, Alberto Redaelli, Marco Rasponi
Published in: Future Science OA, Issue 3/2, 2017, Page(s) FSO191, ISSN 2056-5623
Publisher: Future Science
DOI: 10.4155/fsoa-2017-0024

4D Flow Analysis of BAV-Related Fluid-Dynamic Alterations: Evidences of Wall Shear Stress Alterations in Absence of Clinically-Relevant Aortic Anatomical Remodeling

Author(s): Filippo Piatti, Francesco Sturla, Malenka M. Bissell, Selene Pirola, Massimo Lombardi, Igor Nesteruk, Alessandro Della Corte, Alberto C. L. Redaelli, Emiliano Votta
Published in: Frontiers in Physiology, Issue 8, 2017, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2017.00441

The role of biomechanics in aortic aneurysm management: requirements, open problems and future prospects

Author(s): Dario Farotto, Patrick Segers, Bart Meuris, Jos Vander Sloten, Nele Famaey
Published in: Journal of the Mechanical Behavior of Biomedical Materials, Issue 77, 2018, Page(s) 295-307, ISSN 1751-6161
Publisher: Elsevier BV
DOI: 10.1016/j.jmbbm.2017.08.019

Patient-Specific Computer Simulation to Elucidate the Role of Contact Pressure in the Development of New Conduction Abnormalities After Catheter-Based Implantation of a Self-Expanding Aortic Valve

Author(s): Giorgia Rocatello, Nahid El Faquir, Gianluca De Santis, Francesco Iannaccone, Johan Bosmans, Ole De Backer, Lars Sondergaard, Patrick Segers, Matthieu De Beule, Peter de Jaegere, Peter Mortier
Published in: Circulation: Cardiovascular Interventions, Issue 11/2, 2018, Page(s) e005344, ISSN 1941-7640
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCINTERVENTIONS.117.005344

85Patient-specific computer simulation to elucidate the role of contact pressure in the development of new conduction abnormalities after catheter based implantation of a self-expanding aortic valve

Author(s): G. Rocatello, N. El Faquir, G. De Santis, F. Iannaccone, J. Bosmans, O. De Backer, L. Sondergaard, P. Segers, M. De Beule, P. De Jaegere, P. Mortier
Published in: European Heart Journal, Issue 38/suppl_1, 2017, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehx501.85

TCT-785 Low implantation depth during TAVR increases the pressure exerted on the atrioventricular conduction system: a biomechanical analysis

Author(s): Giorgia Rocatello, Nahid El Faquir, Patrick Segers, Peter Mortier, Peter de Jaegere
Published in: Journal of the American College of Cardiology, Issue 70/18, 2017, Page(s) B267-B268, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2017.09.669

A novel system for the treatment of aortic annular dilation: an ex vivo investigation

Author(s): Pallav Shah, Claudia Romagnoni, Michal Jaworek, Federico Lucherini, Monica Contino, Alan Menkis, Guido Gelpi, Gianfranco B Fiore, Carlo Antona, Riccardo Vismara
Published in: European Journal of Cardio-Thoracic Surgery, Issue 52/6, 2017, Page(s) 1090-1097, ISSN 1010-7940
Publisher: Elsevier BV
DOI: 10.1093/ejcts/ezx203

Modelling of Lesions Associated with Functional Mitral Regurgitation in an Ex Vivo Platform

Author(s): Michal Jaworek, Federico Lucherini, Claudia Romagnoni, Guido Gelpi, Monica Contino, Paolo Romitelli, Carlo Antona, Gianfranco B. Fiore, Riccardo Vismara
Published in: Annals of Biomedical Engineering, Issue 45/10, 2017, Page(s) 2324-2334, ISSN 0090-6964
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10439-017-1885-6

Functional Tricuspid Regurgitation Model in a Beating Heart Platform

Author(s): Michal Jaworek, Marco Piola, Federico Lucherini, Guido Gelpi, Marco Castagna, Giuliana Lentini, Carlo Antona, Gianfranco B. Fiore, Riccardo Vismara
Published in: ASAIO Journal, Issue 63/4, 2017, Page(s) 438-444, ISSN 1058-2916
Publisher: American Society For Artificial Internal Organs
DOI: 10.1097/MAT.0000000000000510

In vitro and in silico approaches to quantify the effects of the Mitraclip ® system on mitral valve function

Author(s): Francesco Sturla, Riccardo Vismara, Michal Jaworek, Emiliano Votta, Paolo Romitelli, Omar A. Pappalardo, Federico Lucherini, Carlo Antona, Gianfranco B. Fiore, Alberto Redaelli
Published in: Journal of Biomechanics, Issue 50, 2017, Page(s) 83-92, ISSN 0021-9290
Publisher: Elsevier BV
DOI: 10.1016/j.jbiomech.2016.11.013

P1370Ex-vivo pathological models of mitral and tricuspid regurgitation for realistic clinical training and new treatment approaches evaluation

Author(s): M. Jaworek, G. Gelpi, F. Lucherini, C. Romagnoni, M. Contino, A. Mangini, P. Romitelli, M. Piola, C. Antona, G.B. Fiore, R. Vismara
Published in: European Heart Journal, Issue 38/suppl_1, 2017, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehx502.P1370

P4888Right ventricular papillary muscles approximation for functional tricuspid regurgitation treatment - in-vitro feasibility study

Author(s): M. Jaworek, F. Lucherini, G. Gelpi, C. Romagnoni, C. Antona, G.B. Fiore, R. Vismara
Published in: European Heart Journal, Issue 38/suppl_1, 2017, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehx493.P4888

From 4D Medical Images (CT, MRI, and Ultrasound) to 4D Structured Mesh Models of the Left Ventricular Endocardium for Patient-Specific Simulations

Author(s): Federico Canè, Benedict Verhegghe, Matthieu De Beule, Philippe B. Bertrand, Rob J. Van der Geest, Patrick Segers, Gianluca De Santis
Published in: BioMed Research International, Issue 2018, 2018, Page(s) 1-14, ISSN 2314-6133
Publisher: Hindawi Publishing Corporation
DOI: 10.1155/2018/7030718

Towards the improved quantification of in vivo abnormal wall shear stresses in BAV-affected patients from 4D-flow imaging: Benchmarking and application to real data

Author(s): F. Piatti, S. Pirola, M. Bissell, I. Nesteruk, F. Sturla, A. Della Corte, A. Redaelli, E. Votta
Published in: Journal of Biomechanics, Issue 50, 2017, Page(s) 93-101, ISSN 0021-9290
Publisher: Elsevier BV
DOI: 10.1016/j.jbiomech.2016.11.044

Hemodynamic evaluation using four-dimensional flow magnetic resonance imaging for a patient with multichanneled aortic dissection

Author(s): Baolei Guo, Selene Pirola, Daqiao Guo, Zhihui Dong, Xiao Yun Xu, Weiguo Fu
Published in: Journal of Vascular Surgery Cases and Innovative Techniques, Issue 4/1, 2018, Page(s) 67-71, ISSN 2468-4287
Publisher: Society for Vascular Surgery - Elsevier
DOI: 10.1016/j.jvscit.2017.11.005

On the choice of outlet boundary conditions for patient-specific analysis of aortic flow using computational fluid dynamics

Author(s): S. Pirola, Z. Cheng, O.A. Jarral, D.P. O'Regan, J.R. Pepper, T. Athanasiou, X.Y. Xu
Published in: Journal of Biomechanics, Issue 60, 2017, Page(s) 15-21, ISSN 0021-9290
Publisher: Elsevier BV
DOI: 10.1016/j.jbiomech.2017.06.005

Computational study of aortic hemodynamics for patients with an abnormal aortic valve: The importance of secondary flow at the ascending aorta inlet

Author(s): S. Pirola, O. A. Jarral, D. P. O'Regan, G. Asimakopoulos, J. R. Anderson, J. R. Pepper, T. Athanasiou, X. Y. Xu
Published in: APL Bioengineering, Issue 2/2, 2018, Page(s) 026101, ISSN 2473-2877
Publisher: AIP Publishing
DOI: 10.1063/1.5011960

A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: towards <i>in situ</i> tissue-engineered vascular accesses for haemodialysis

Author(s): Sebastião van Uden, Noemi Vanerio, Valentina Catto, Barbara Bonandrini, Matteo Tironi, Marina Figliuzzi, Andrea Remuzzi, Linda Kock, Alberto Redaelli, Francesco G Greco, Stefania Adele Riboldi
Published in: Biomedical Materials, 2019, ISSN 1748-6041
Publisher: Institute of Physics Publishing
DOI: 10.1088/1748-605x/aafc96

Electrospun fibroin/polyurethane hybrid meshes: Manufacturing, characterization, and potentialities as substrates for haemodialysis arteriovenous grafts

Author(s): Sebastião van Uden, Valentina Catto, Giovanni Perotto, Athanassia Athanassiou, Alberto C. L. Redaelli, Francesco G. Greco, Stefania A. Riboldi
Published in: Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2018, ISSN 1552-4973
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jbm.b.34177

TCT-17 Tricuspid Valve Regurgitation Reduction Following Concomitant Subvalvular and Annulus-level Treatment – Ex-vivo Study

Author(s): Michal Jaworek, Claudia Romagnoni, Omar Pappalardo, Matteo Selmi, Guido Gelpi, Federico Lucherini, Alberto Redaelli, Gianfranco Fiore, Emiliano Votta, Carlo Antona, Riccardo Vismara
Published in: Journal of the American College of Cardiology, Issue 72/13, 2018, Page(s) B8, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2018.08.1095

RIGHT VENTRICULAR PAPILLARY MUSCLES APPROXIMATION: INSIGHT FROM EX VIVO FUNCTIONAL TRUCISPID REGURGITATION MODEL

Author(s): Michal Jaworek, Omar A. Pappalardo, Matteo Selmi, Guido Gelpi, Federico Lucherini, Claudia Romagnoni, Carlo Antona, Alberto Redaelli, Gianfranco B. Fiore, Emiliano Votta, Riccardo Vismara
Published in: Journal of the American College of Cardiology, Issue 71/11, 2018, Page(s) A1351, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/s0735-1097(18)31892-8

Microfabricated Physiological Models for In Vitro Drug Screening Applications

Author(s): Giovanni Stefano Ugolini, Daniela Cruz-Moreira, Roberta Visone, Alberto Redaelli, Marco Rasponi
Published in: Micromachines, Issue 7(12), 2016, Page(s) 233, ISSN 2072-666X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi7120233

Transcatheter Edge-to-Edge Treatment of Functional Tricuspid Regurgitation in an Ex Vivo Pulsatile Heart Model

Author(s): Vismara R, Gelpi G, Prabhu S, Romitelli P, Troxler LG, Mangini A, Romagnoni C, Contino M, Van Hoven DT, Lucherini F, Jaworek M, Redaelli A, Fiore GB, Antona C.
Published in: Journal of the American College of Cardiology, Issue 68(10), 2016, Page(s) 1023-33, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2016.06.022

A new approach to approximate the effects of pre-stress in arteries

Author(s): Farotto, Dario; Smoljkić, Marija; Segers, Patrick; Vander Sloten, Jos; Famaey, Nele
Published in: EUROMECH Colloquium 585 : Advanced experimental methods in tissue biomechanics, Issue 41, 2017
Publisher: EUROMECH

IMPROVING ARTERIAL MATERIAL CHARACTERIZATION BY INCLUDING DEPOSITION STRETCHES

Author(s): Maes, Lauranne; Fehervary ,Heleen; Vastmans, Julie; Farotto, Dario; Mousavi, Jamalledin S.; Vander Sloten, Jos; Avril, Stephane; Famaey, Nele
Published in: 5 th International Conference on Computational and Mathematical Biomedical Engineering - CMBE2017, Issue 1, 2017, Page(s) 214-217
Publisher: International Conference on Computational and Mathematical Biomedical Engineering

Novel predictors for conduction disturbances after Transcatheter Aortic Valve Implantation

Author(s): Rocatello, Giorgia; De Beule, Matthieu; de Jaegere, Peter; Bosmans, Johan; Segers, Patrick; Mortier, Peter
Published in: 2016
Publisher: VPH Institute

Computer simulations to predict paravalvular leakage after TAVI: a comparison between Medtronic CoreValve and Medtronic CoreValve Evolut R Systems

Author(s): Rocatello, Giorgia; De Beule, Matthieu; Segers, Patrick; de Jaegere, Peter; Mortier, Peter
Published in: 2016
Publisher: VPH Institute

Low implantation depth during TAVR increases the pressure exerted on the atrioventricular conduction system: a biomechanical analysis

Author(s): Rocatello, Giorgia; El Faquir, Nahid; Segers, Patrick; De Beule, Matthieu; Mortier, Peter; de Jaegere, Peter
Published in: 2017
Publisher: National Day of Biomedical Engineering

Development And Assessment Of Passive Beating Right Heart Platform For Cardiovascular Devices Testing And Realistic Surgical Training

Author(s): Jaworek, Michal; Lucherini, Federico; Gelpi, Guido; Antona, Carlo; Fiore, Gianfranco B.; Vismara, Riccardo
Published in: Int J Artif Organs, Issue 39(7), 2016, Page(s) 359-393
Publisher: Wichtig

Functional Mitral Regurgitation Model in an Ex-Vivo Platform

Author(s): Jaworek, Michal; Lucherini, Federico; Romagnoni, Claudia; Gelpi, Guido; Contino, Monica; Romitelli, Paolo; Antona, Carlo; Fiore, Gianfranco B.; Vismara, Riccardo
Published in: Int J Artif Organs, Issue 40(8), 2017, Page(s) 382 - 428
Publisher: Wichtig

Ex vivo pathological platform for vascular device testing

Author(s): Vanerio, Noemi; Leopaldi, Alberto; Stijnen, Marco; de Hart, Jurgen; de Mol, Bas; Kock, Linda
Published in: ASAIO Journal, ASAIO 63rd Annual Conference, 2017
Publisher: ASAIO

P219 Novel cantilever-based approach for force measurement of 3D engineered cardiac microtissue within a microfluidic platform

Author(s): Cruz-Moreira, Daniela; Votta, Emiliano; Redaelli, Alberto; Rasponi, Marco
Published in: eCM Conferences Meeting Abstracts Information – Collection 2: Personalised Therapies for Regenerative Medicine; TERMIS-EU 2017 Conference, 26-30 June 2017, Davos, Switzerland, Issue Collection 2, 2017, Page(s) 171, ISSN 2522-235X
Publisher: eCM

Influence of inlet boundary conditions on the evaluation of aortic wall shear stress for patients with abnormal aortic valves

Author(s): Pirola, Selene; Jarral, Omar A.; O’Regan, Declan P.; Athanasiou, Thanos; Xu, Xiao Yun
Published in: 2017, Page(s) Abstract 103
Publisher: Summer Biomechanics, Bioengineering and Biotransport Organizing Committee

Towards the development of a pathological ex vivo blood vessel model

Author(s): Vanerio, Noemi; Leopaldi, Alberto; Stijnen, Marco; de Mol, Bas; Kock, Linda
Published in: 12th international symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, 2017
Publisher: 12th international symposium on Biomechanics in Vascular Biology and Cardiovascular Disease

Anisotropic Field‐of‐View support for 3D Golden Angle Kooshball Imaging

Author(s): Guruprasad Krishnamoorthy, Jouke Smink, Marc Kouwenhoven, Marcel Breeuwer
Published in: European Society for Magnetic Resonance in Medicine, Issue "Abstract # 997, 2017", 2017
Publisher: European Society for Magnetic Resonance in Medicine

Propagation of Left Ventricular Endocardial Boundary Segmentation in Time-Resolved 3D Cardiac MR

Author(s): Belsley G, Tourais J, Breeuwer M.
Published in: ESMRMB 34th Scientific Meeting, 2017
Publisher: ESMRMB

Mapping mesh tool for left ventricle modeling

Author(s): Canè, Federico; De Santis, Gianluca; Bavo, Alessandra; Segers, Patrick.
Published in: 2016
Publisher: National Day of Biomedical Engineering

Quantification of intracardiac flow

Author(s): Canè, Federico; De Santis, Gianluca; Bavo, Alessandra; Segers, Patrick.
Published in: 2016
Publisher: VPH Institute

Ex Vivo Culture Platform To Characterize And Monitor The Onset, Progression And Treatment of Vascular Pathologies.

Author(s): Vanerio N, Stijnen M, van Beusekom HM, van Soest G, de Mol BAJM, Kock LM
Published in: ASAIO journal, proceedings of 64th Annual Conference, 2018
Publisher: ASAIO Journal, proceedings of 64th Annual Conference

Ex vivo platforms for tissue-engineered heart valve assessment: a step towards clinical translation.

Author(s): Vanerio N, Stijnen M, de Hart J, de Mol BAJM, Kock LM
Published in: Proceedings of 1st International Conference of Tissue-Engineered Heart Valves., 2018
Publisher: 1st International Conference of Tissue-Engineered Heart Valves

Does left ventricular torsion affect intraventricular fluid dynamics?

Author(s): Canè Federico; De Santis Gianluca; Degroote Joris; Segers Patrick
Published in: 2018
Publisher: Belgian National Committee for Biomedical Engineering

Impact of left ventricular torsion on flow dynamics: a CFD modeling study using the overset mesh method

Author(s): Canè Federico; De Santis Gianluca; Segers Patrick; Degroote Joris
Published in: Abstracts ofthe 8th World Congress of Biomechanics, 2018
Publisher: Society of Biomechanics

Towards realistic and tailored medical image generation with artificial intelligence

Author(s): Astudillo P
Published in: National Day on Biomedical Engineering: Data sciences and Healthcare, 2018
Publisher: NCBME

Automatic annulus perimeter sizing from MDCT using deep learning

Author(s): Astudillo P, Mortier P, Bosmans J, De Backer O, de Jaegere P, De Beule M, Dambre J
Published in: 5th European Congress on eCardiology and eHealth, 2018
Publisher: Europa Organisation

3D Golden Angle Stack-of-Stars with Anisotropic Field-of-View

Author(s): Tourais J, Krishnamoorthy G, Kouwenhoven M, Smink J, Breeuwer M
Published in: Proceedings ISMRM, Issue Abstract 4143, 2018
Publisher: ISMRM

3D Golden Angle Stack-of-Stars with Anisotropic Field-of-View

Author(s): J. Tourais, G. Krishnamoorthy, M. Kouwenhoven, J. Smink and M. Breeuwer
Published in: Proceedings ISMRM Benelux Chapter, Issue Abstract P-2, 2018
Publisher: ISMRM Benelux

A novel imaged-based approach for tricuspid valve biomechanical evaluation through finite element modelling

Author(s): Selmi M, Pappalardo OA, Aversa A, Careddu E, Jaworek M, Vismara R, Luciani GB, Faggian G, Redaelli A, Votta E
Published in: 2018
Publisher: World congress of Biomechnics

4D-Flow MRI based non-invasive hemodynamic assessment and diagnosis in aortic coarctations

Author(s): Saitta S, Pirola S, Piatti F, Votta E, Pluchinotta F, Xu XY, Redaelli A
Published in: 2018
Publisher: world congress of Biomechanics

In-vitro three-dimensional hemodynamic mapping of surgically implanted pericardial valves through 4D Flow MRI.

Author(s): Piatti F, Tasca G, Jaworek M, Lucherini F, Sturla F, Pluchinotta F, Greiser A, Fiore GB, Vismara R, Votta E, Gamba A, Lombardi M, Redaelli A
Published in: 2018
Publisher: world congress of Biomechnics

Quantification of the Aortic Hemodynamicsafter Transcatheter Aortic Valve Implantation Combining 3d-Printing, 4d PC-MRI and Computational Fluid Dynamics

Author(s): Pirola S, Sturla F, Lucherini F, Vismara R, Jaworek M, Saitta S, DeMarco F, Pluchinotta F, Lombardi M, Piatti F, Fiore GB, Redaelli A, Votta E, Xu XY
Published in: 2018
Publisher: world congress of Biomechanics

Tricuspid valve transcatheter treatments assessment in a passive beating heart platform

Author(s): Jaworek M, Pappalardo OA, Lucherini F, Selmi M, Gelpi G, Romagnoni C, Romitelli P, Prabhu S, Antona C, Redaelli A, Fiore GB, Votta E, Vismara R
Published in: 2018
Publisher: Worls congress of Biomechanics

Self-gated respiratory-resolved 5D Flow MRI using the 3D spiral phyllotaxis trajectory

Author(s): Monica Sigovan, Gastao Cruz, Torben Schneider, Juan Felipe Perez-Juste Abascal, Cyril Mory, Guruprasad Krishnamoorty, Rene Botnar, Philippe Douek, Claudia Prieto, and Loic Boussel
Published in: Proceedings ISMRM, Issue Abstract 4897, 2018
Publisher: ISMRM

Free-breathing volumetric Fat-Water separation using 3D Golden-Angle Kooshball trajectory with anisotropic field-of-views - A feasibility study

Author(s): Guruprasad Krishnamoorthy, Jouke Smink, Marc Kouwenhoven, Marcel Breeuwer
Published in: Proceedings ISMRM Benelux Chapter, Issue Abstract O-23, 2018
Publisher: ISMRM

Landmark propagation over cardiac 4D-CT using non-rigid registration

Author(s): Farotto D, Vanden Berghe P, Wirix-Speetjens R, Vander Sloten J.
Published in: 2018
Publisher: Springer

DEVELOPMENT AND ASSESSMENT OF PASSIVE BEATING RIGHT HEART PLATFORM FOR CARDIOVASCULAR DEVICES TESTING AND REALISTIC SURGICAL TRAINING

Author(s): Jaworek M., Lucherini F., Gelpi G., Antona C., Fiore G., Vismara R.
Published in: International Journal of Artificial Organs, Issue 39(7), 2016
Publisher: Wichtig International Limited

Optimization Of The Fatigue Resistance Of Nitinol Stents Through Shot Peening

Author(s): Konstantinos Dimakos, Andrea Mariotto, Fausto Giacosa
Published in: Procedia Structural Integrity, Issue Volume 2, 2016, 2016, Page(s) Pages 1522–1529
Publisher: ELSEVIER
DOI: 10.1016/j.prostr.2016.06.193

Aortic Flow Hemodynamics after Surgical Aortic Valve Replacement: Comparison with a Healthy Subject

Author(s): Selene Pirola, Zhuo Cheng, Omar A. Jarral, Declan P. O’regan, Thanos Athanasiou, Xiao Y. Xu
Published in: Virtual Physiological Human 2016 Conference, Issue September 2016, 2016
Publisher: VPH 2016

Intellectual Property Rights

Hybrid scaffold suitable for regenerating animal tissues and process for producing the scaffold

Application/Publication number: WO 2018077475A1
Date: 2017-10-27
Applicant(s): BIOENGINEERING LABORATORIES

Silkothane

Application/Publication number: EUIPO 16507063
Date: 2017-03-24
Applicant(s): BIOENGINEERING LABORATORIES

Deliverables

Publications

Intellectual Property Rights

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