MUltiSectoral Integrative approaches to CArdiac care

Risultati finali

Organization of an international conference

MUSICA web site release

Pubblicazioni

Tailoring cardiac environment in microphysiological systems: an outlook on current and perspective heart-on-chip platforms

Autori: Giovanni Stefano Ugolini, Roberta Visone, Daniela Cruz-Moreira, Alberto Redaelli, Marco Rasponi
Pubblicato in: Future Science OA, Numero 3/2, 2017, Pagina/e FSO191, ISSN 2056-5623
Editore: Future Science
DOI: 10.4155/fsoa-2017-0024

4D Flow Analysis of BAV-Related Fluid-Dynamic Alterations: Evidences of Wall Shear Stress Alterations in Absence of Clinically-Relevant Aortic Anatomical Remodeling

Autori: Filippo Piatti, Francesco Sturla, Malenka M. Bissell, Selene Pirola, Massimo Lombardi, Igor Nesteruk, Alessandro Della Corte, Alberto C. L. Redaelli, Emiliano Votta
Pubblicato in: Frontiers in Physiology, Numero 8, 2017, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2017.00441

The role of biomechanics in aortic aneurysm management: requirements, open problems and future prospects

Autori: Dario Farotto, Patrick Segers, Bart Meuris, Jos Vander Sloten, Nele Famaey
Pubblicato in: Journal of the Mechanical Behavior of Biomedical Materials, Numero 77, 2018, Pagina/e 295-307, ISSN 1751-6161
Editore: Elsevier BV
DOI: 10.1016/j.jmbbm.2017.08.019

Patient-Specific Computer Simulation to Elucidate the Role of Contact Pressure in the Development of New Conduction Abnormalities After Catheter-Based Implantation of a Self-Expanding Aortic Valve

Autori: Giorgia Rocatello, Nahid El Faquir, Gianluca De Santis, Francesco Iannaccone, Johan Bosmans, Ole De Backer, Lars Sondergaard, Patrick Segers, Matthieu De Beule, Peter de Jaegere, Peter Mortier
Pubblicato in: Circulation: Cardiovascular Interventions, Numero 11/2, 2018, Pagina/e e005344, ISSN 1941-7640
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCINTERVENTIONS.117.005344

85Patient-specific computer simulation to elucidate the role of contact pressure in the development of new conduction abnormalities after catheter based implantation of a self-expanding aortic valve

Autori: G. Rocatello, N. El Faquir, G. De Santis, F. Iannaccone, J. Bosmans, O. De Backer, L. Sondergaard, P. Segers, M. De Beule, P. De Jaegere, P. Mortier
Pubblicato in: European Heart Journal, Numero 38/suppl_1, 2017, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehx501.85

TCT-785 Low implantation depth during TAVR increases the pressure exerted on the atrioventricular conduction system: a biomechanical analysis

Autori: Giorgia Rocatello, Nahid El Faquir, Patrick Segers, Peter Mortier, Peter de Jaegere
Pubblicato in: Journal of the American College of Cardiology, Numero 70/18, 2017, Pagina/e B267-B268, ISSN 0735-1097
Editore: Elsevier BV
DOI: 10.1016/j.jacc.2017.09.669

A novel system for the treatment of aortic annular dilation: an ex vivo investigation

Autori: Pallav Shah, Claudia Romagnoni, Michal Jaworek, Federico Lucherini, Monica Contino, Alan Menkis, Guido Gelpi, Gianfranco B Fiore, Carlo Antona, Riccardo Vismara
Pubblicato in: European Journal of Cardio-Thoracic Surgery, Numero 52/6, 2017, Pagina/e 1090-1097, ISSN 1010-7940
Editore: Elsevier BV
DOI: 10.1093/ejcts/ezx203

Modelling of Lesions Associated with Functional Mitral Regurgitation in an Ex Vivo Platform

Autori: Michal Jaworek, Federico Lucherini, Claudia Romagnoni, Guido Gelpi, Monica Contino, Paolo Romitelli, Carlo Antona, Gianfranco B. Fiore, Riccardo Vismara
Pubblicato in: Annals of Biomedical Engineering, Numero 45/10, 2017, Pagina/e 2324-2334, ISSN 0090-6964
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10439-017-1885-6

Functional Tricuspid Regurgitation Model in a Beating Heart Platform

Autori: Michal Jaworek, Marco Piola, Federico Lucherini, Guido Gelpi, Marco Castagna, Giuliana Lentini, Carlo Antona, Gianfranco B. Fiore, Riccardo Vismara
Pubblicato in: ASAIO Journal, Numero 63/4, 2017, Pagina/e 438-444, ISSN 1058-2916
Editore: American Society For Artificial Internal Organs
DOI: 10.1097/MAT.0000000000000510

In vitro and in silico approaches to quantify the effects of the Mitraclip ® system on mitral valve function

Autori: Francesco Sturla, Riccardo Vismara, Michal Jaworek, Emiliano Votta, Paolo Romitelli, Omar A. Pappalardo, Federico Lucherini, Carlo Antona, Gianfranco B. Fiore, Alberto Redaelli
Pubblicato in: Journal of Biomechanics, Numero 50, 2017, Pagina/e 83-92, ISSN 0021-9290
Editore: Elsevier BV
DOI: 10.1016/j.jbiomech.2016.11.013

P1370Ex-vivo pathological models of mitral and tricuspid regurgitation for realistic clinical training and new treatment approaches evaluation

Autori: M. Jaworek, G. Gelpi, F. Lucherini, C. Romagnoni, M. Contino, A. Mangini, P. Romitelli, M. Piola, C. Antona, G.B. Fiore, R. Vismara
Pubblicato in: European Heart Journal, Numero 38/suppl_1, 2017, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehx502.P1370

P4888Right ventricular papillary muscles approximation for functional tricuspid regurgitation treatment - in-vitro feasibility study

Autori: M. Jaworek, F. Lucherini, G. Gelpi, C. Romagnoni, C. Antona, G.B. Fiore, R. Vismara
Pubblicato in: European Heart Journal, Numero 38/suppl_1, 2017, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehx493.P4888

From 4D Medical Images (CT, MRI, and Ultrasound) to 4D Structured Mesh Models of the Left Ventricular Endocardium for Patient-Specific Simulations

Autori: Federico Canè, Benedict Verhegghe, Matthieu De Beule, Philippe B. Bertrand, Rob J. Van der Geest, Patrick Segers, Gianluca De Santis
Pubblicato in: BioMed Research International, Numero 2018, 2018, Pagina/e 1-14, ISSN 2314-6133
Editore: Hindawi Publishing Corporation
DOI: 10.1155/2018/7030718

Towards the improved quantification of in vivo abnormal wall shear stresses in BAV-affected patients from 4D-flow imaging: Benchmarking and application to real data

Autori: F. Piatti, S. Pirola, M. Bissell, I. Nesteruk, F. Sturla, A. Della Corte, A. Redaelli, E. Votta
Pubblicato in: Journal of Biomechanics, Numero 50, 2017, Pagina/e 93-101, ISSN 0021-9290
Editore: Elsevier BV
DOI: 10.1016/j.jbiomech.2016.11.044

Hemodynamic evaluation using four-dimensional flow magnetic resonance imaging for a patient with multichanneled aortic dissection

Autori: Baolei Guo, Selene Pirola, Daqiao Guo, Zhihui Dong, Xiao Yun Xu, Weiguo Fu
Pubblicato in: Journal of Vascular Surgery Cases and Innovative Techniques, Numero 4/1, 2018, Pagina/e 67-71, ISSN 2468-4287
Editore: Society for Vascular Surgery - Elsevier
DOI: 10.1016/j.jvscit.2017.11.005

On the choice of outlet boundary conditions for patient-specific analysis of aortic flow using computational fluid dynamics

Autori: S. Pirola, Z. Cheng, O.A. Jarral, D.P. O'Regan, J.R. Pepper, T. Athanasiou, X.Y. Xu
Pubblicato in: Journal of Biomechanics, Numero 60, 2017, Pagina/e 15-21, ISSN 0021-9290
Editore: Elsevier BV
DOI: 10.1016/j.jbiomech.2017.06.005

Computational study of aortic hemodynamics for patients with an abnormal aortic valve: The importance of secondary flow at the ascending aorta inlet

Autori: S. Pirola, O. A. Jarral, D. P. O'Regan, G. Asimakopoulos, J. R. Anderson, J. R. Pepper, T. Athanasiou, X. Y. Xu
Pubblicato in: APL Bioengineering, Numero 2/2, 2018, Pagina/e 026101, ISSN 2473-2877
Editore: AIP Publishing
DOI: 10.1063/1.5011960

A novel hybrid silk-fibroin/polyurethane three-layered vascular graft: towards <i>in situ</i> tissue-engineered vascular accesses for haemodialysis

Autori: Sebastião van Uden, Noemi Vanerio, Valentina Catto, Barbara Bonandrini, Matteo Tironi, Marina Figliuzzi, Andrea Remuzzi, Linda Kock, Alberto Redaelli, Francesco G Greco, Stefania Adele Riboldi
Pubblicato in: Biomedical Materials, 2019, ISSN 1748-6041
Editore: Institute of Physics Publishing
DOI: 10.1088/1748-605x/aafc96

Electrospun fibroin/polyurethane hybrid meshes: Manufacturing, characterization, and potentialities as substrates for haemodialysis arteriovenous grafts

Autori: Sebastião van Uden, Valentina Catto, Giovanni Perotto, Athanassia Athanassiou, Alberto C. L. Redaelli, Francesco G. Greco, Stefania A. Riboldi
Pubblicato in: Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2018, ISSN 1552-4973
Editore: John Wiley & Sons Inc.
DOI: 10.1002/jbm.b.34177

TCT-17 Tricuspid Valve Regurgitation Reduction Following Concomitant Subvalvular and Annulus-level Treatment – Ex-vivo Study

Autori: Michal Jaworek, Claudia Romagnoni, Omar Pappalardo, Matteo Selmi, Guido Gelpi, Federico Lucherini, Alberto Redaelli, Gianfranco Fiore, Emiliano Votta, Carlo Antona, Riccardo Vismara
Pubblicato in: Journal of the American College of Cardiology, Numero 72/13, 2018, Pagina/e B8, ISSN 0735-1097
Editore: Elsevier BV
DOI: 10.1016/j.jacc.2018.08.1095

RIGHT VENTRICULAR PAPILLARY MUSCLES APPROXIMATION: INSIGHT FROM EX VIVO FUNCTIONAL TRUCISPID REGURGITATION MODEL

Autori: Michal Jaworek, Omar A. Pappalardo, Matteo Selmi, Guido Gelpi, Federico Lucherini, Claudia Romagnoni, Carlo Antona, Alberto Redaelli, Gianfranco B. Fiore, Emiliano Votta, Riccardo Vismara
Pubblicato in: Journal of the American College of Cardiology, Numero 71/11, 2018, Pagina/e A1351, ISSN 0735-1097
Editore: Elsevier BV
DOI: 10.1016/s0735-1097(18)31892-8

Microfabricated Physiological Models for In Vitro Drug Screening Applications

Autori: Giovanni Stefano Ugolini, Daniela Cruz-Moreira, Roberta Visone, Alberto Redaelli, Marco Rasponi
Pubblicato in: Micromachines, Numero 7(12), 2016, Pagina/e 233, ISSN 2072-666X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi7120233

Transcatheter Edge-to-Edge Treatment of Functional Tricuspid Regurgitation in an Ex Vivo Pulsatile Heart Model

Autori: Vismara R, Gelpi G, Prabhu S, Romitelli P, Troxler LG, Mangini A, Romagnoni C, Contino M, Van Hoven DT, Lucherini F, Jaworek M, Redaelli A, Fiore GB, Antona C.
Pubblicato in: Journal of the American College of Cardiology, Numero 68(10), 2016, Pagina/e 1023-33, ISSN 0735-1097
Editore: Elsevier BV
DOI: 10.1016/j.jacc.2016.06.022

A new approach to approximate the effects of pre-stress in arteries

Autori: Farotto, Dario; Smoljkić, Marija; Segers, Patrick; Vander Sloten, Jos; Famaey, Nele
Pubblicato in: EUROMECH Colloquium 585 : Advanced experimental methods in tissue biomechanics, Numero 41, 2017
Editore: EUROMECH

IMPROVING ARTERIAL MATERIAL CHARACTERIZATION BY INCLUDING DEPOSITION STRETCHES

Autori: Maes, Lauranne; Fehervary ,Heleen; Vastmans, Julie; Farotto, Dario; Mousavi, Jamalledin S.; Vander Sloten, Jos; Avril, Stephane; Famaey, Nele
Pubblicato in: 5 th International Conference on Computational and Mathematical Biomedical Engineering - CMBE2017, Numero 1, 2017, Pagina/e 214-217
Editore: International Conference on Computational and Mathematical Biomedical Engineering

Novel predictors for conduction disturbances after Transcatheter Aortic Valve Implantation

Autori: Rocatello, Giorgia; De Beule, Matthieu; de Jaegere, Peter; Bosmans, Johan; Segers, Patrick; Mortier, Peter
Pubblicato in: 2016
Editore: VPH Institute

Computer simulations to predict paravalvular leakage after TAVI: a comparison between Medtronic CoreValve and Medtronic CoreValve Evolut R Systems

Autori: Rocatello, Giorgia; De Beule, Matthieu; Segers, Patrick; de Jaegere, Peter; Mortier, Peter
Pubblicato in: 2016
Editore: VPH Institute

Low implantation depth during TAVR increases the pressure exerted on the atrioventricular conduction system: a biomechanical analysis

Autori: Rocatello, Giorgia; El Faquir, Nahid; Segers, Patrick; De Beule, Matthieu; Mortier, Peter; de Jaegere, Peter
Pubblicato in: 2017
Editore: National Day of Biomedical Engineering

Development And Assessment Of Passive Beating Right Heart Platform For Cardiovascular Devices Testing And Realistic Surgical Training

Autori: Jaworek, Michal; Lucherini, Federico; Gelpi, Guido; Antona, Carlo; Fiore, Gianfranco B.; Vismara, Riccardo
Pubblicato in: Int J Artif Organs, Numero 39(7), 2016, Pagina/e 359-393
Editore: Wichtig

Functional Mitral Regurgitation Model in an Ex-Vivo Platform

Autori: Jaworek, Michal; Lucherini, Federico; Romagnoni, Claudia; Gelpi, Guido; Contino, Monica; Romitelli, Paolo; Antona, Carlo; Fiore, Gianfranco B.; Vismara, Riccardo
Pubblicato in: Int J Artif Organs, Numero 40(8), 2017, Pagina/e 382 - 428
Editore: Wichtig

Ex vivo pathological platform for vascular device testing

Autori: Vanerio, Noemi; Leopaldi, Alberto; Stijnen, Marco; de Hart, Jurgen; de Mol, Bas; Kock, Linda
Pubblicato in: ASAIO Journal, ASAIO 63rd Annual Conference, 2017
Editore: ASAIO

P219 Novel cantilever-based approach for force measurement of 3D engineered cardiac microtissue within a microfluidic platform

Autori: Cruz-Moreira, Daniela; Votta, Emiliano; Redaelli, Alberto; Rasponi, Marco
Pubblicato in: eCM Conferences Meeting Abstracts Information – Collection 2: Personalised Therapies for Regenerative Medicine; TERMIS-EU 2017 Conference, 26-30 June 2017, Davos, Switzerland, Numero Collection 2, 2017, Pagina/e 171, ISSN 2522-235X
Editore: eCM

Influence of inlet boundary conditions on the evaluation of aortic wall shear stress for patients with abnormal aortic valves

Autori: Pirola, Selene; Jarral, Omar A.; O’Regan, Declan P.; Athanasiou, Thanos; Xu, Xiao Yun
Pubblicato in: 2017, Pagina/e Abstract 103
Editore: Summer Biomechanics, Bioengineering and Biotransport Organizing Committee

Towards the development of a pathological ex vivo blood vessel model

Autori: Vanerio, Noemi; Leopaldi, Alberto; Stijnen, Marco; de Mol, Bas; Kock, Linda
Pubblicato in: 12th international symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, 2017
Editore: 12th international symposium on Biomechanics in Vascular Biology and Cardiovascular Disease

Anisotropic Field‐of‐View support for 3D Golden Angle Kooshball Imaging

Autori: Guruprasad Krishnamoorthy, Jouke Smink, Marc Kouwenhoven, Marcel Breeuwer
Pubblicato in: European Society for Magnetic Resonance in Medicine, Numero "Abstract # 997, 2017", 2017
Editore: European Society for Magnetic Resonance in Medicine

Propagation of Left Ventricular Endocardial Boundary Segmentation in Time-Resolved 3D Cardiac MR

Autori: Belsley G, Tourais J, Breeuwer M.
Pubblicato in: ESMRMB 34th Scientific Meeting, 2017
Editore: ESMRMB

Mapping mesh tool for left ventricle modeling

Autori: Canè, Federico; De Santis, Gianluca; Bavo, Alessandra; Segers, Patrick.
Pubblicato in: 2016
Editore: National Day of Biomedical Engineering

Quantification of intracardiac flow

Autori: Canè, Federico; De Santis, Gianluca; Bavo, Alessandra; Segers, Patrick.
Pubblicato in: 2016
Editore: VPH Institute

Ex Vivo Culture Platform To Characterize And Monitor The Onset, Progression And Treatment of Vascular Pathologies.

Autori: Vanerio N, Stijnen M, van Beusekom HM, van Soest G, de Mol BAJM, Kock LM
Pubblicato in: ASAIO journal, proceedings of 64th Annual Conference, 2018
Editore: ASAIO Journal, proceedings of 64th Annual Conference

Ex vivo platforms for tissue-engineered heart valve assessment: a step towards clinical translation.

Autori: Vanerio N, Stijnen M, de Hart J, de Mol BAJM, Kock LM
Pubblicato in: Proceedings of 1st International Conference of Tissue-Engineered Heart Valves., 2018
Editore: 1st International Conference of Tissue-Engineered Heart Valves

Does left ventricular torsion affect intraventricular fluid dynamics?

Autori: Canè Federico; De Santis Gianluca; Degroote Joris; Segers Patrick
Pubblicato in: 2018
Editore: Belgian National Committee for Biomedical Engineering

Impact of left ventricular torsion on flow dynamics: a CFD modeling study using the overset mesh method

Autori: Canè Federico; De Santis Gianluca; Segers Patrick; Degroote Joris
Pubblicato in: Abstracts ofthe 8th World Congress of Biomechanics, 2018
Editore: Society of Biomechanics

Towards realistic and tailored medical image generation with artificial intelligence

Autori: Astudillo P
Pubblicato in: National Day on Biomedical Engineering: Data sciences and Healthcare, 2018
Editore: NCBME

Automatic annulus perimeter sizing from MDCT using deep learning

Autori: Astudillo P, Mortier P, Bosmans J, De Backer O, de Jaegere P, De Beule M, Dambre J
Pubblicato in: 5th European Congress on eCardiology and eHealth, 2018
Editore: Europa Organisation

3D Golden Angle Stack-of-Stars with Anisotropic Field-of-View

Autori: Tourais J, Krishnamoorthy G, Kouwenhoven M, Smink J, Breeuwer M
Pubblicato in: Proceedings ISMRM, Numero Abstract 4143, 2018
Editore: ISMRM

3D Golden Angle Stack-of-Stars with Anisotropic Field-of-View

Autori: J. Tourais, G. Krishnamoorthy, M. Kouwenhoven, J. Smink and M. Breeuwer
Pubblicato in: Proceedings ISMRM Benelux Chapter, Numero Abstract P-2, 2018
Editore: ISMRM Benelux

A novel imaged-based approach for tricuspid valve biomechanical evaluation through finite element modelling

Autori: Selmi M, Pappalardo OA, Aversa A, Careddu E, Jaworek M, Vismara R, Luciani GB, Faggian G, Redaelli A, Votta E
Pubblicato in: 2018
Editore: World congress of Biomechnics

4D-Flow MRI based non-invasive hemodynamic assessment and diagnosis in aortic coarctations

Autori: Saitta S, Pirola S, Piatti F, Votta E, Pluchinotta F, Xu XY, Redaelli A
Pubblicato in: 2018
Editore: world congress of Biomechanics

In-vitro three-dimensional hemodynamic mapping of surgically implanted pericardial valves through 4D Flow MRI.

Autori: Piatti F, Tasca G, Jaworek M, Lucherini F, Sturla F, Pluchinotta F, Greiser A, Fiore GB, Vismara R, Votta E, Gamba A, Lombardi M, Redaelli A
Pubblicato in: 2018
Editore: world congress of Biomechnics

Quantification of the Aortic Hemodynamicsafter Transcatheter Aortic Valve Implantation Combining 3d-Printing, 4d PC-MRI and Computational Fluid Dynamics

Autori: Pirola S, Sturla F, Lucherini F, Vismara R, Jaworek M, Saitta S, DeMarco F, Pluchinotta F, Lombardi M, Piatti F, Fiore GB, Redaelli A, Votta E, Xu XY
Pubblicato in: 2018
Editore: world congress of Biomechanics

Tricuspid valve transcatheter treatments assessment in a passive beating heart platform

Autori: Jaworek M, Pappalardo OA, Lucherini F, Selmi M, Gelpi G, Romagnoni C, Romitelli P, Prabhu S, Antona C, Redaelli A, Fiore GB, Votta E, Vismara R
Pubblicato in: 2018
Editore: Worls congress of Biomechanics

Self-gated respiratory-resolved 5D Flow MRI using the 3D spiral phyllotaxis trajectory

Autori: Monica Sigovan, Gastao Cruz, Torben Schneider, Juan Felipe Perez-Juste Abascal, Cyril Mory, Guruprasad Krishnamoorty, Rene Botnar, Philippe Douek, Claudia Prieto, and Loic Boussel
Pubblicato in: Proceedings ISMRM, Numero Abstract 4897, 2018
Editore: ISMRM

Free-breathing volumetric Fat-Water separation using 3D Golden-Angle Kooshball trajectory with anisotropic field-of-views - A feasibility study

Autori: Guruprasad Krishnamoorthy, Jouke Smink, Marc Kouwenhoven, Marcel Breeuwer
Pubblicato in: Proceedings ISMRM Benelux Chapter, Numero Abstract O-23, 2018
Editore: ISMRM

Landmark propagation over cardiac 4D-CT using non-rigid registration

Autori: Farotto D, Vanden Berghe P, Wirix-Speetjens R, Vander Sloten J.
Pubblicato in: 2018
Editore: Springer

DEVELOPMENT AND ASSESSMENT OF PASSIVE BEATING RIGHT HEART PLATFORM FOR CARDIOVASCULAR DEVICES TESTING AND REALISTIC SURGICAL TRAINING

Autori: Jaworek M., Lucherini F., Gelpi G., Antona C., Fiore G., Vismara R.
Pubblicato in: International Journal of Artificial Organs, Numero 39(7), 2016
Editore: Wichtig International Limited

Optimization Of The Fatigue Resistance Of Nitinol Stents Through Shot Peening

Autori: Konstantinos Dimakos, Andrea Mariotto, Fausto Giacosa
Pubblicato in: Procedia Structural Integrity, Numero Volume 2, 2016, 2016, Pagina/e Pages 1522–1529
Editore: ELSEVIER
DOI: 10.1016/j.prostr.2016.06.193

Aortic Flow Hemodynamics after Surgical Aortic Valve Replacement: Comparison with a Healthy Subject

Autori: Selene Pirola, Zhuo Cheng, Omar A. Jarral, Declan P. O’regan, Thanos Athanasiou, Xiao Y. Xu
Pubblicato in: Virtual Physiological Human 2016 Conference, Numero September 2016, 2016
Editore: VPH 2016

Diritti di proprietà intellettuale

Hybrid scaffold suitable for regenerating animal tissues and process for producing the scaffold

Numero candidatura/pubblicazione: WO 2018077475A1
Data: 2017-10-27
Candidato/i: BIOENGINEERING LABORATORIES

Silkothane

Numero candidatura/pubblicazione: EUIPO 16507063
Data: 2017-03-24
Candidato/i: BIOENGINEERING LABORATORIES

Risultati finali

Pubblicazioni

Diritti di proprietà intellettuale

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