Control of leishmaniasis, from bench to bedside and community

Risultati finali

Outcome of the recruitment meeting organised in M4

Scientific publications and other modes of dissemination and outreach

Compilation of publications, presentations and other modes of dissemination conducted by the network participants

Pubblicazioni

Phlebotomine mortality effect of systemic insecticides administered to dogs

Autori: Sonia Ares Gomez, Javier Lucientes Curdi, Juan Antonio Castillo Hernandez, Paz Peris Peris, Adriana Esteban Gil, Ronald Vladimir Oropeza Velasquez, Paula Ortega Hernandez, Albert Picado
Pubblicato in: Parasites & Vectors, Numero 11/1, 2018, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-018-2820-x

Severity of Chagasic Cardiomyopathy Is Associated With Response to a Novel Rapid Diagnostic Test for Trypanosoma cruzi TcII/V/VI

Autori: Tapan Bhattacharyya, Louisa A Messenger, Caryn Bern, Pascal Mertens, Quentin Gilleman, Nicolas Zeippen, Bruno C Bremer Hinckel, Niamh Murphy, Robert H Gilman, Michael A Miles, Jorge Flores, Roni Colanzi, Ricardo Bozo, Gerson Galdos, Manuela Verastegui, Gerardo Sanchez, Emi Okamoto, Jackie Sherbuck, Toria Rendell, Vishal Shah, Malasa Jois, Diana Marti
Pubblicato in: Clinical Infectious Diseases, Numero 67/4, 2018, Pagina/e 519-524, ISSN 1058-4838
Editore: University of Chicago Press
DOI: 10.1093/cid/ciy121

Relation between Skin Pharmacokinetics and Efficacy in AmBisome Treatment of Murine Cutaneous Leishmaniasis

Autori: Gert-Jan Wijnant, Katrien Van Bocxlaer, Vanessa Yardley, Andy Harris, Sudaxshina Murdan, Simon L. Croft
Pubblicato in: Antimicrobial Agents and Chemotherapy, Numero 62/3, 2018, ISSN 0066-4804
Editore: American Society for Microbiology
DOI: 10.1128/AAC.02009-17

Systemic insecticide treatment of the canine reservoir of Trypanosoma cruzi induces high levels of lethality in Triatoma infestans, a principal vector of Chagas disease

Autori: Ariel Loza, Adrianna Talaga, Gladys Herbas, Ruben Jair Canaviri, Thalia Cahuasiri, Laura Luck, Alvaro Guibarra, Raquel Goncalves, Juan Antonio Pereira, Sonia A. Gomez, Albert Picado, Louisa Alexandra Messenger, Caryn Bern, Orin Courtenay
Pubblicato in: Parasites & Vectors, Numero 10/1, 2017, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-017-2278-2

Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome ® and AmBisome ® in murine cutaneous leishmaniasis

Autori: Gert-Jan Wijnant, Katrien Van Bocxlaer, Vanessa Yardley, Andy Harris, Mo Alavijeh, Rita Silva-Pedrosa, Sandra Antunes, Isabel Mauricio, Sudaxshina Murdan, Simon L. Croft
Pubblicato in: International Journal for Parasitology: Drugs and Drug Resistance, Numero 8/2, 2018, Pagina/e 223-228, ISSN 2211-3207
Editore: Elsevier BV
DOI: 10.1016/j.ijpddr.2018.04.001

Why miltefosine—a life-saving drug for leishmaniasis—is unavailable to people who need it the most

Autori: Temmy Sunyoto, Julien Potet, Marleen Boelaert
Pubblicato in: BMJ Global Health, Numero 3/3, 2018, Pagina/e e000709, ISSN 2059-7908
Editore: BMJ Publishing Group
DOI: 10.1136/bmjgh-2018-000709

Evaluation of the rSP03B sero-strip, a newly proposed rapid test for canine exposure to Phlebotomus perniciosus, vector of Leishmania infantum

Autori: Laura Willen, Pascal Mertens, Petr Volf
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 12/8, 2018, Pagina/e e0006607, ISSN 1935-2735
Editore: Public Library of Science
DOI: 10.1371/journal.pntd.0006607

Open-Source Electronic Health Record Systems for Low-Resource Settings: Systematic Review

Autori: Assel Syzdykova, André Malta, Maria Zolfo, Ermias Diro, José Luis Oliveira
Pubblicato in: JMIR Medical Informatics, Numero 5/4, 2017, Pagina/e e44, ISSN 2291-9694
Editore: JMIR Publications
DOI: 10.2196/medinform.8131

Importance of secondary screening with clinical isolates for anti-leishmania drug discovery

Autori: Aya Hefnawy, Juan Cantizani, Imanol Peña, Pilar Manzano, Suman Rijal, Jean-Claude Dujardin, Geraldine De Muylder, Julio Martin
Pubblicato in: Scientific Reports, Numero 8/1, 2018, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-018-30040-5

“Kala-Azar is a Dishonest Disease”: Community Perspectives on Access Barriers to Visceral Leishmaniasis (Kala-Azar) Diagnosis and Care in Southern Gadarif, Sudan

Autori: Temmy Sunyoto, Atia M. Atia, Koert Ritmeijer, Rabie Ali Babiker, Gamal K. Adam, Catiane Vander Kelen, Albert Picado, Gabriel Alcoba, Margriet den Boer, Yassin Hamid, Marleen Boelaert, Nugdalla Abdelrahman
Pubblicato in: The American Journal of Tropical Medicine and Hygiene, Numero 98/4, 2018, Pagina/e 1091-1101, ISSN 0002-9637
Editore: American Society of Tropical Medicine and Hygiene
DOI: 10.4269/ajtmh.17-0872

Visceral leishmaniasis in Somalia: A review of epidemiology and access to care

Autori: Temmy Sunyoto, Julien Potet, Marleen Boelaert
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 11/3, 2017, Pagina/e e0005231, ISSN 1935-2735
Editore: PLOS Neglected Tropical Diseases
DOI: 10.1371/journal.pntd.0005231

Estimating the efficacy of community-wide use of systemic insecticides in dogs to control zoonotic visceral leishmaniasis: A modelling study in a Brazilian scenario

Autori: Sonia A. Gomez, Lloyd A. C. Chapman, Erin Dilger, Orin Courtenay, Albert Picado
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 12/9, 2018, Pagina/e e0006797, ISSN 1935-2735
Editore: Public Library of Science
DOI: 10.1371/journal.pntd.0006797

Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B

Autori: Gert-Jan Wijnant, Katrien Van Bocxlaer, Amanda Fortes Francisco, Vanessa Yardley, Andy Harris, Mo Alavijeh, Sudaxshina Murdan, Simon L. Croft
Pubblicato in: Antimicrobial Agents and Chemotherapy, Numero 62/10, 2018, ISSN 0066-4804
Editore: American Society for Microbiology
DOI: 10.1128/AAC.00631-18

Advances toward Diagnostic Tools for Managing Zoonotic Visceral Leishmaniasis

Autori: Malcolm S. Duthie, Aurore Lison, Orin Courtenay
Pubblicato in: Trends in Parasitology, Numero 34/10, 2018, Pagina/e 881-890, ISSN 1471-4922
Editore: Elsevier BV
DOI: 10.1016/j.pt.2018.07.012

Seasonal dynamics of canine antibody response to Phlebotomus perniciosus saliva in an endemic area of Leishmania infantum

Autori: Rita Velez, Tatiana Spitzova, Ester Domenech, Laura Willen, Jordi Cairó, Petr Volf, Montserrat Gállego
Pubblicato in: Parasites & Vectors, Numero 11/1, 2018, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-018-3123-y

Detection of IgG1 against rK39 improves monitoring of treatment outcome in visceral leishmaniasis

Autori: Guy Mollett, Bruno C Bremer Hinckel, Tapan Bhattacharyya, Tegwen Marlais, Om Prakash Singh, Pascal Mertens, Andrew K Falconar, Sayda El-Safi, Shyam Sundar, Michael A Miles
Pubblicato in: Clinical Infectious Diseases, 2018, ISSN 1058-4838
Editore: University of Chicago Press
DOI: 10.1093/cid/ciy1062

Visceral Leishmaniasis IgG1 Rapid Monitoring of Cure vs. Relapse, and Potential for Diagnosis of Post Kala-Azar Dermal Leishmaniasis

Autori: Tegwen Marlais, Tapan Bhattacharyya, Om Prakash Singh, Pascal Mertens, Quentin Gilleman, Caroline Thunissen, Bruno C. Bremer Hinckel, Callum Pearson, Bathsheba L. Gardner, Stephanie Airs, Marianne de la Roche, Kiera Hayes, Hannah Hafezi, Andrew K. Falconar, Osama Eisa, Alfarazdeg Saad, Basudha Khanal, Narayan Raj Bhattarai, Suman Rijal, Marleen Boelaert, Sayda El-Safi, Shyam Sundar, Michael A. Mil
Pubblicato in: Frontiers in Cellular and Infection Microbiology, Numero 8, 2018, ISSN 2235-2988
Editore: Frontiers Media S. A.
DOI: 10.3389/fcimb.2018.00427

The Unknown Nature of the Antigen in the Direct Agglutination Test for Visceral Leishmaniasis Hampers Development of Serodiagnostic Tests

Autori: Vera Kühne, Philippe Büscher
Pubblicato in: The American Journal of Tropical Medicine and Hygiene, 2018, ISSN 0002-9637
Editore: American Society of Tropical Medicine and Hygiene
DOI: 10.4269/ajtmh.18-0740

Uncharted territory of the epidemiological burden of cutaneous leishmaniasis in sub-Saharan Africa—A systematic review

Autori: Temmy Sunyoto, Kristien Verdonck, Sayda el Safi, Julien Potet, Albert Picado, Marleen Boelaert
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 12/10, 2018, Pagina/e e0006914, ISSN 1935-2735
Editore: Public Library of Science
DOI: 10.1371/journal.pntd.0006914

Cost Effectiveness of New Diagnostic Tools for Cutaneous Leishmaniasis in Afghanistan

Autori: Céline Aerts, Martijn Vink, Sayed Jalal Pashtoon, Sami Nahzat, Albert Picado, Israel Cruz, Elisa Sicuri
Pubblicato in: Applied Health Economics and Health Policy, 2018, ISSN 1175-5652
Editore: Open Mind Journals
DOI: 10.1007/s40258-018-0449-8

Trypanosomatid Infections: How Do Parasites and Their Excreted–Secreted Factors Modulate the Inducible Metabolism of l-Arginine in Macrophages?

Autori: Philippe Holzmuller, Anne Geiger, Romaric Nzoumbou-Boko, Joana Pissarra, Sarra Hamrouni, Valérie Rodrigues, Frédéric-Antoine Dauchy, Jean-Loup Lemesre, Philippe Vincendeau, Rachel Bras-Gonçalves
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
Editore: Lausanne : Frontiers Research Foundation
DOI: 10.3389/fimmu.2018.00778

A randomized, blinded, controlled trial to assess sand fly mortality of fluralaner administered orally in dogs

Autori: Sonia Ares Gomez, Javier Lucientes, Juan Antonio Castillo, Maria Paz Peris, Sarah Delacour, Paula Ortega, Ronald-Vladimir Oropeza, Albert Picado
Pubblicato in: Parasites & Vectors, Numero 11/1, 2018, ISSN 1756-3305
Editore: BioMed Central
DOI: 10.1186/s13071-018-3231-8

Seroprevalence of canine Leishmania infantum infection in the Mediterranean region and identification of risk factors: The example of North-Eastern and Pyrenean areas of Spain

Autori: R. Velez, C. Ballart, E. Domenech, A. Abras, A. Fernández-Arévalo, S.A. Gómez, S. Tebar, C. Muñoz, J. Cairó, M. Gállego
Pubblicato in: Preventive Veterinary Medicine, Numero 162, 2019, Pagina/e 67-75, ISSN 0167-5877
Editore: Elsevier BV
DOI: 10.1016/j.prevetmed.2018.10.015

The recombinant protein rSP03B is a valid antigen for screening dog exposure to Phlebotomus perniciosus across foci of canine leishmaniasis

Autori: T. KOSTALOVA, T. LESTINOVA, C. MAIA, P. SUMOVA, M. VLKOVA, L. WILLEN, N. POLANSKA, E. FIORENTINO, A. SCALONE, G. OLIVA, F. VERONESI, J. M. CRISTÓVÃO, O. COURTENAY, L. CAMPINO, L. GRADONI, M. GRAMICCIA, P. VOLF
Pubblicato in: Medical and Veterinary Entomology, Numero 31/1, 2017, Pagina/e 88-93, ISSN 0269-283X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/mve.12192

Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis

Autori: Gert-Jan Wijnant, Katrien Van Bocxlaer, Vanessa Yardley, Sudaxshina Murdan, Simon L. Croft
Pubblicato in: Antimicrobial Agents and Chemotherapy, Numero 61/8, 2017, Pagina/e e00358-17, ISSN 0066-4804
Editore: American Society for Microbiology
DOI: 10.1128/AAC.00358-17

Exploiting Knowledge on Leishmania Drug Resistance to Support the Quest for New Drugs

Autori: Aya Hefnawy, Maya Berg, Jean-Claude Dujardin, Géraldine De Muylder
Pubblicato in: Trends in Parasitology, Numero 33/3, 2017, Pagina/e 162-174, ISSN 1471-4922
Editore: Elsevier BV
DOI: 10.1016/j.pt.2016.11.003

Systemic insecticides used in dogs: potential candidates for phlebotomine vector control?

Autori: Sonia Ares Gomez, Albert Picado
Pubblicato in: Tropical Medicine & International Health, Numero 22/6, 2017, Pagina/e 755-764, ISSN 1360-2276
Editore: Blackwell Publishing Inc.
DOI: 10.1111/tmi.12870

Are public-private partnerships the solution to tackle neglected tropical diseases? A systematic review of the literature

Autori: Céline Aerts, Temmy Sunyoto, Fabrizio Tediosi, Elisa Sicuri
Pubblicato in: Health Policy, Numero 121/7, 2017, Pagina/e 745-754, ISSN 0168-8510
Editore: Elsevier BV
DOI: 10.1016/j.healthpol.2017.05.005

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