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Plasmonic-based autOmated lab-on-chip SEnsor for the rapid In-situ Detection of LegiONella

Objetivo

Legionnaires’ disease is a serious form of pneumonia caused by bacterium Legionella pneumophila, with a case-fatality ratio on the order of 10-15%. L. pneumophila proliferates in aquatic habitats, especially in potable water, air conditioning, hot and cold water systems, cooling towers, evaporative condensers, spa/natural pools. Actually, its detection and monitoring rely on time-consuming protocols (in the order of several days) based on in-vitro selective bacteria culture methods, performed by highly specialized personnel in dedicated laboratories. POSEIDON project targets to change the approach in bacteriological environmental monitoring and in infection risk management by developing a fully automatic and reliable system. Handling of the air/water sample will be designed and integrated in preconditioning system and microfluidic device through which whole bacteria cells will be transported from the sampling module to the sensing plasmonic surface. The complete measure protocol will be integrated and performed according to EU legislation guidelines. Specificity will be ensured by immuno-functionalization of gratings surfaces and enhanced system sensitivity will be granted by the optimization of the optical detection system architecture. Sensors based on Grating Coupled Surface Plasmon Resonance (GC-SPR) in azimuthally rotating configuration have recently proved sensitivity enhancement up to almost two orders of magnitude. Furthermore, the symmetry breaking related to grating rotation allows exploiting the incident polarization, more easily controlled with respect to incidence wavelength and angles interrogation. The prototype will be designed to be integrated in water distribution or HVAC systems in order to demonstrate its feasibility in industrially relevant fields and to open new applications and new market opportunities. POSEIDON project aims to address new solutions in this relevant health and safety societal challenge.

Convocatoria de propuestas

H2020-ICT-2014

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Convocatoria de subcontratación

H2020-ICT-2014-1

Régimen de financiación

RIA - Research and Innovation action

Coordinador

CLIVET SPA
Aportación neta de la UEn
€ 626 125,00
Dirección
VIA CAMP LONC 25 FRAZIONE VILLAPAI ERA
32032 Feltre
Italia

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Región
Nord-Est Veneto Belluno
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Enlaces
Coste total
€ 626 125,00

Participantes (6)