Systematic exploration of peroxisomal structure and function

Project Information

PeroxiSystem

Grant agreement ID: 646604

DOI

10.3030/646604

Project closed

EC signature date 13 March 2015

Start date 1 September 2015

End date 31 August 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

WEIZMANN INSTITUTE OF SCIENCE
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (21)

A piggybacking mechanism enables peroxisomal localization of the glyoxylate cycle enzyme Mdh2 in yeast

Author(s): Shiran Gabay-Maskit, Luis Daniel Cruz-Zaragoza, Nadav Shai, Miriam Eisenstein, Chen Bibi, Nir Cohen, Tobias Hansen, Eden Yifrach, Nofar Harpaz, Ruth Belostotsky, Wolfgang Schliebs, Maya Schuldiner, Ralf Erdmann, Einat Zalckvar
Published in: Journal of Cell Science, 2021, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.244376

YeastRGB: comparing the abundance and localization of yeast proteins across cells and libraries

Author(s): Benjamin Dubreuil, Ehud Sass, Yotam Nadav, Meta Heidenreich, Joseph M Georgeson, Uri Weill, Yuanqiang Duan, Matthias Meurer, Maya Schuldiner, Michael Knop, Emmanuel D Levy
Published in: Nucleic Acids Research, Issue 47/D1, 2018, Page(s) D1245-D1249, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gky941

Pex14p Phosphorylation Modulates Import of Citrate Synthase 2 Into Peroxisomes in Saccharomyces cerevisiae

Author(s): Andreas Schummer, Renate Maier, Shiran Gabay-Maskit, Tobias Hansen, Wignand W. D. Mühlhäuser, Ida Suppanz, Amir Fadel, Maya Schuldiner, Wolfgang Girzalsky, Silke Oeljeklaus, Einat Zalckvar, Ralf Erdmann, Bettina Warscheid
Published in: Frontiers in Cell and Developmental Biology, Issue 8, 2020, ISSN 2296-634X
Publisher: Frontiers Journal
DOI: 10.3389/fcell.2020.549451

Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins

Author(s): Justyna P. Wróblewska, Luis Daniel Cruz-Zaragoza, Wei Yuan, Andreas Schummer, Silvia G. Chuartzman, Rinse de Boer, Silke Oeljeklaus, Maya Schuldiner, Einat Zalckvar, Bettina Warscheid, Ralf Erdmann, Ida J. van der Klei
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Issue 1864/10, 2017, Page(s) 1656-1667, ISSN 0167-4889
Publisher: Elsevier BV
DOI: 10.1016/j.bbamcr.2017.05.021

Mind the Organelle Gap – Peroxisome Contact Sites in Disease

Author(s): Inês Gomes Castro, Maya Schuldiner, Einat Zalckvar
Published in: Trends in Biochemical Sciences, Issue 43/3, 2018, Page(s) 199-210, ISSN 0968-0004
Publisher: Elsevier BV
DOI: 10.1016/j.tibs.2018.01.001

Database for HIgh Throughput Screening hits (dHITS): A simple tool to retrieve gene specific phenotypes from systematic screens done in yeast

Author(s): Silvia G. Chuartzman, Maya Schuldiner
Published in: Yeast, 2018, ISSN 0749-503X
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/yea.3312

Validation of a yeast malate dehydrogenase 2 (Mdh2) antibody tested for use in western blots

Author(s): Shiran Gabay-Maskit, Maya Schuldiner, Einat Zalckvar
Published in: F1000Research, Issue 7, 2018, Page(s) 130, ISSN 2046-1402
Publisher: F1000 Research Ltd.
DOI: 10.12688/f1000research.13396.1

Defining the Mammalian Peroxisomal Proteome

Author(s): Eden Yifrach, Sven Fischer, Silke Oeljeklaus, Maya Schuldiner, Einat Zalckvar, Bettina Warscheid
Published in: Subcellular Biochememistry, 2018, Page(s) 47-66, ISSN 0306-0225
Publisher: Plenum Publishers
DOI: 10.1007/978-981-13-2233-4_2

Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

Author(s): Nadav Shai, Eden Yifrach, Carlo W. T. van Roermund, Nir Cohen, Chen Bibi, Lodewijk IJlst, Laetitia Cavellini, Julie Meurisse, Ramona Schuster, Lior Zada, Muriel C. Mari, Fulvio M. Reggiori, Adam L. Hughes, Mafalda Escobar-Henriques, Mickael M. Cohen, Hans R. Waterham, Ronald J. A. Wanders, Maya Schuldiner, Einat Zalckvar
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-03957-8

Genome-wide SWAp-Tag yeast libraries for proteome exploration

Author(s): Uri Weill, Ido Yofe, Ehud Sass, Bram Stynen, Dan Davidi, Janani Natarajan, Reut Ben-Menachem, Zohar Avihou, Omer Goldman, Nofar Harpaz, Silvia Chuartzman, Kiril Kniazev, Barbara Knoblach, Janina Laborenz, Felix Boos, Jacqueline Kowarzyk, Shifra Ben-Dor, Einat Zalckvar, Johannes M. Herrmann, Richard A. Rachubinski, Ophry Pines, Doron Rapaport, Stephen W. Michnick, Emmanuel D. Levy, Maya Schuldiner
Published in: Nature Methods, Issue 15/8, 2018, Page(s) 617-622, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-018-0044-9

Characterization of proteome dynamics in oleate reveals a novel peroxisome targeting receptor

Author(s): Eden Yifrach, Silvia G. Chuartzman, Noa Dahan, Shiran Maskit, Lior Zada, Uri Weill, Ido Yofe, Tsviya Olender, Maya Schuldiner, Einat Zalckvar
Published in: Journal of Cell Science, 2016, Page(s) jcs.195255, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.195255

A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites

Author(s): Michal Eisenberg-Bord, Nadav Shai, Maya Schuldiner, Maria Bohnert
Published in: Developmental Cell, Issue 39/4, 2016, Page(s) 395-409, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2016.10.022

No peroxisome is an island — Peroxisome contact sites

Author(s): Nadav Shai, Maya Schuldiner, Einat Zalckvar
Published in: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Issue 1863/5, 2016, Page(s) 1061-1069, ISSN 0167-4889
Publisher: Elsevier BV
DOI: 10.1016/j.bbamcr.2015.09.016

Peroxisystem: Harnessing systems cell biology to study peroxisomes

Author(s): Maya Schuldiner, Einat Zalckvar
Published in: Biology of the Cell, Issue 107/4, 2015, Page(s) 89-97, ISSN 0248-4900
Publisher: Portland Press, Ltd.
DOI: 10.1111/boc.201400091

Pex35 is a regulator of peroxisome abundance

Author(s): Ido Yofe, Kareem Soliman, Silvia G. Chuartzman, Bruce Morgan, Uri Weill, Eden Yifrach, Tobias P. Dick, Sara J. Cooper, Christer S. Ejsing, Maya Schuldiner, Einat Zalckvar, Sven Thoms
Published in: Journal of Cell Science, Issue 130/4, 2017, Page(s) 791-804, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.187914

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

Author(s): Ido Yofe, Uri Weill, Matthias Meurer, Silvia Chuartzman, Einat Zalckvar, Omer Goldman, Shifra Ben-Dor, Conny Schütze, Nils Wiedemann, Michael Knop, Anton Khmelinskii, Maya Schuldiner
Published in: Nature Methods, Issue 13/4, 2016, Page(s) 371-378, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/nmeth.3795

Coming together to define membrane contact sites

Author(s): Luca Scorrano, Maria Antonietta De Matteis, Scott Emr, Francesca Giordano, György Hajnóczky, Benoît Kornmann, Laura L. Lackner, Tim P. Levine, Luca Pellegrini, Karin Reinisch, Rosario Rizzuto, Thomas Simmen, Harald Stenmark, Christian Ungermann, Maya Schuldiner
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-09253-3

Protein Topology Prediction Algorithms Systematically Investigated in the Yeast Saccharomyces cerevisiae

Author(s): Uri Weill, Nir Cohen, Amir Fadel, Shifra Ben‐Dor, Maya Schuldiner
Published in: BioEssays, Issue 41/8, 2019, Page(s) 1800252, ISSN 0265-9247
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/bies.201800252

High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding

Author(s): Yury S. Bykov, Nir Cohen, Natalia Gabrielli, Hetty Manenschijn, Sonja Welsch, Petr Chlanda, Wanda Kukulski, Kiran R. Patil, Maya Schuldiner, John A.G. Briggs
Published in: Journal of Cell Biology, Issue 218/8, 2019, Page(s) 2797-2811, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.201812081

Assessment of GFP Tag Position on Protein Localization and Growth Fitness in Yeast

Author(s): Uri Weill, Gat Krieger, Zohar Avihou, Ron Milo, Maya Schuldiner, Dan Davidi
Published in: Journal of Molecular Biology, Issue 431/3, 2019, Page(s) 636-641, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2018.12.004

Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay

Author(s): Mira Rosenthal, Eyal Metzl-Raz, Jérôme Bürgi, Eden Yifrach, Layla Drwesh, Amir Fadel, Yoav Peleg, Doron Rapaport, Matthias Wilmanns, Naama Barkai, Maya Schuldiner, Einat Zalckvar
Published in: Proceedings of the National Academy of Sciences, Issue 117/35, 2020, Page(s) 21432-21440, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1920078117

Book chapters (1)

Peroxisome Mini-Libraries: Systematic Approaches to Study Peroxisomes Made Easy.

Author(s): Noa Dahan, Maya Schuldiner, Einat Zalckvar
Published in: Methods Mol Biol, 2017, Page(s) 305-318
Publisher: Springer New York
DOI: 10.1007/978-1-4939-6937-1_28

Non-peer reviewed articles (1)

Incredibly close—A newly identified peroxisome–ER contact site in humans

Author(s): Maya Schuldiner, Einat Zalckvar
Published in: Journal of Cell Biology, Issue 216/2, 2017, Page(s) 287-289, ISSN 0021-9525
Publisher: Rockefeller University Press
DOI: 10.1083/jcb.201701072