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Structure and Dynamics of Low-Complexity Regions in Proteins: The Huntingtin Case

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Evidence of the Reduced Abundance of Proline cis Conformation in Protein Poly Proline Tracts

Author(s): Annika Urbanek; Matija Popovic; Carlos A. Elena-Real; Anna Morató; Alejandro Estaña; Aurélie Fournet; Frédéric Allemand; Ana M. Gil; Carlos Cativiela; Juan Cortés; Ana I. Jiménez; Nathalie Sibille; Pau Bernadó
Published in: Journal of the American Chemical Society, 142, 2020, Page(s) 7976, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c02263

Site-Specific Isotopic Labeling (SSIL): Access to High-Resolution Structural and Dynamic Information in Low-Complexity Proteins.

Author(s): Urbanek, Annika; Elena‐Real, Carlos A.; Popovic, Matija; Morató, Anna; Fournet, Aurélie; Allemand, Frédéric; Delbecq, Stephane; Sibille, Nathalie; Bernadó, Pau
Published in: ChemBioChem, 5, 2020, Page(s) 769-775, ISSN 1439-7633
Publisher: Wiley-VCH GmbH
DOI: 10.1002/cbic.201900583

Realistic Ensemble Models of Intrinsically Disordered Proteins Using a Structure-Encoding Coil Database

Author(s): Alejandro Estaña, Nathalie Sibille, Elise Delaforge, Marc Vaisset, Juan Cortés, Pau Bernadó
Published in: Structure, 27, 2019, Page(s) 381-391, ISSN 0969-2126
Publisher: Cell Press
DOI: 10.1016/j.str.2018.10.016

Disentangling the complexity of low complexity proteins

Author(s): Pablo Mier, Lisanna Paladin, Stella Tamana, Sophia Petrosian, Borbála Hajdu-Soltész, Annika Urbanek, Aleksandra Gruca, Dariusz Plewczynski, Marcin Grynberg, Pau Bernadó, Zoltán Gáspári, Christos A Ouzounis, Vasilis J Promponas, Andrey V Kajava, John M Hancock, Silvio C E Tosatto, Zsuzsanna Dosztanyi, Miguel A Andrade-Navarro
Published in: Briefings in Bioinformatics, 21, 2020, Page(s) 458-472, ISSN 1467-5463
Publisher: Oxford University Press
DOI: 10.1093/bib/bbz007

The importance of definitions in the study of polyQ regions: A tale of thresholds, impurities and sequence context.

Author(s): Pablo Mier; Carlos A. Elena-Real; Annika Urbanek; Pau Bernadó; Miguel A. Andrade-Navarro
Published in: Computational and Structural Biotechnology Journal, 18, 2020, Page(s) 306-313, ISSN 2001-0370
Publisher: Elsevier
DOI: 10.1016/j.csbj.2020.01.012

Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins

Author(s): Annika Urbanek, Matija Popovic, Anna Morató, Alejandro Estaña, Carlos A Elena-Real, Pablo Mier, Aurélie Fournet, Frédéric Allemand, Stephane Delbecq, Miguel A Andrade-Navarro, Juan Cortés, Nathalie Sibille, Pau Bernadó
Published in: Structure, 28, 2020, Page(s) 733-746, ISSN 0969-2126
Publisher: Cell Press
DOI: 10.1016/j.str.2020.04.008

Robust Cell-Free Expression of Sub-Pathological and Pathological Huntingtin Exon-1 for NMR Studies. General Approaches for the Isotopic Labeling of Low-Complexity Proteins

Author(s): Anna Morató, Carlos A Elena-Real, Matija Popovic, Aurélie Fournet, Karen Zhang, Frédéric Allemand, Nathalie Sibille, Annika Urbanek, Pau Bernadó
Published in: Biomolecules, 10, 2020, Page(s) 1458, ISSN 2218-273X
Publisher: MDPI
DOI: 10.3390/biom10101458

Investigating the Formation of Structural Elements in Proteins Using Local Sequence-Dependent Information and a Heuristic Search Algorithm

Author(s): Estaña, Alejandro; Ghallab, Malik; Bernadó, Pau; Cortés, Juan
Published in: Molecules, 24, 2019, Page(s) 1150, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24061150

Predicting Secondary Structure Propensities in IDPs Using Simple Statistics from Three-Residue Fragments

Author(s): Alejandro Estaña, Amélie Barozet, Assia Mouhand, Marc Vaisset, Christophe Zanon, Pierre Fauret, Nathalie Sibille, Pau Bernadó, Juan Cortés
Published in: Journal of Molecuar Biology, 432, 2020, Page(s) 5447-5459, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2020.07.026

Solution scattering approaches to dynamical ordering in biomolecular systems

Author(s): Pau Bernadó, Nobutaka Shimizu, Giuseppe Zaccai, Hironari Kamikubo, Masaaki Sugiyama
Published in: Biochimica et Biophysica Acta (BBA) - General Subjects, 1862/2, 2018, Page(s) 253-274, ISSN 0304-4165
Publisher: Elsevier BV
DOI: 10.1016/j.bbagen.2017.10.015

A General Strategy to Access Structural Information at Atomic Resolution in Polyglutamine Homorepeats

Author(s): Annika Urbanek, Anna Morató, Frédéric Allemand, Elise Delaforge, Aurélie Fournet, Matija Popovic, Stephane Delbecq, Nathalie Sibille, Pau Bernadó
Published in: Angewandte Chemie International Edition, 57/14, 2018, Page(s) 3598-3601, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201711530

Hybrid parallelization of a multi-tree path search algorithm: Application to highly-flexible biomolecules

Author(s): Alejandro Estaña, Kevin Molloy, Marc Vaisset, Nathalie Sibille, Thierry Siméon, Pau Bernadó, Juan Cortés
Published in: Parallel Computing, 77, 2018, Page(s) 84-100, ISSN 0167-8191
Publisher: Elsevier BV
DOI: 10.1016/j.parco.2018.06.005

Small-angle scattering studies of intrinsically disordered proteins and their complexes

Author(s): Tiago N Cordeiro, Fátima Herranz-Trillo, Annika Urbanek, Alejandro Estaña, Juan Cortés, Nathalie Sibille, Pau Bernadó
Published in: Current Opinion in Structural Biology, 42, 2017, Page(s) 15-23, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/

Structural Characterization of Highly Flexible Proteins by Small-Angle Scattering.

Author(s): Tiago N. Cordeiro, Fátima Herranz-Trillo, Annika Urbanek, Alejandro Estaña, Juan Cortés, Nathalie Sibille, Pau Bernadó
Published in: Advances in Experimental Medical Biology, 2017, Page(s) 107-129
Publisher: Springer Singapore
DOI: 10.1007/978-981-10-6038-0_7