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Exploring selected long non-coding RNAs as diagnostics and therapeutic targets for heart failure

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Preclinical development of a miR-132 inhibitor for heart failure treatment (opens in new window)

Author(s): Ariana Foinquinos, Sandor Batkai, Celina Genschel, Janika Viereck, Steffen Rump, Mariann Gyöngyösi, Denise Traxler, Martin Riesenhuber, Andreas Spannbauer, Dominika Lukovic, Natalie Weber, Katrin Zlabinger, Ena Hašimbegović, Johannes Winkler, Jan Fiedler, Seema Dangwal, Martin Fischer, Jeanne de la Roche, Daniel Wojciechowski, Theresia Kraft, Rita Garamvölgyi, Sonja Neitzel, Shambhabi Chatter
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-14349-2

Living myocardial slices: a novel multicellular model for cardiac translational research (opens in new window)

Author(s): Filippo Perbellini, Thomas Thum
Published in: European Heart Journal, Issue 41/25, 2019, Page(s) 2405-2408, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehz779

Noncoding RNAs: potential regulators in cardioncology (opens in new window)

Author(s): Shambhabi Chatterjee, Shashi Kumar Gupta, Christian Bär, Thomas Thum
Published in: American Journal of Physiology-Heart and Circulatory Physiology, Issue 316/1, 2019, Page(s) H160-H168, ISSN 0363-6135
Publisher: American Physiological Society
DOI: 10.1152/ajpheart.00418.2018

Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors (opens in new window)

Author(s): Nataliya Gorinski, Monika Bijata, Sonal Prasad, Alexander Wirth, Dalia Abdel Galil, Andre Zeug, Daria Bazovkina, Elena Kondaurova, Elizabeth Kulikova, Tatiana Ilchibaeva, Monika Zareba-Koziol, Francesco Papaleo, Diego Scheggia, Gaga Kochlamazashvili, Alexander Dityatev, Ian Smyth, Adam Krzystyniak, Jakub Wlodarczyk, Diethelm W. Richter, Tatyana Strekalova, Stephan Sigrist, Claudia Bang, Lisa Hobu
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-11876-5

A practical guide for investigating cardiac physiology using living myocardial slices (opens in new window)

Author(s): S. A. Watson, A. Dendorfer, T. Thum, F. Perbellini
Published in: Basic Research in Cardiology, Issue 115/6, 2020, ISSN 0300-8428
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00395-020-00822-y

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy (opens in new window)

Author(s): Janika Viereck, Anne Bührke, Ariana Foinquinos, Shambhabi Chatterjee, Jan A Kleeberger, Ke Xiao, Heike Janssen-Peters, Sandor Batkai, Deepak Ramanujam, Theresia Kraft, Serghei Cebotari, Faikah Gueler, Andreas M Beyer, Jessica Schmitz, Jan H Bräsen, Jan D Schmitto, Mariann Gyöngyösi, Alexandra Löser, Marc N Hirt, Thomas Eschenhagen, Stefan Engelhardt, Christian Bär, Thomas Thum
Published in: European Heart Journal, 2020, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehaa519

Circular RNAs: A Novel Class of Functional RNA Molecules with a Therapeutic Perspective (opens in new window)

Author(s): Laura Santer, Christian Bär, Thomas Thum
Published in: Molecular Therapy, Issue 27/8, 2019, Page(s) 1350-1363, ISSN 1525-0016
Publisher: Nature Publishing Group
DOI: 10.1016/j.ymthe.2019.07.001

Combined high-throughput library screening and next generation RNA sequencing uncover microRNAs controlling human cardiac fibroblast biology (opens in new window)

Author(s): Katharina Schimmel, Stevan D. Stojanović, Cheng-Kai Huang, Mira Jung, Martin H. Meyer, Ke Xiao, Lea Grote-Levi, Christian Bär, Angelika Pfanne, Saskia Mitzka, Annette Just, Robert Geffers, Katharina Bock, Franziska Kenneweg, Felix Kleemiß, Christine S. Falk, Jan Fiedler, Thomas Thum
Published in: Journal of Molecular and Cellular Cardiology, Issue 150, 2021, Page(s) 91-100, ISSN 0022-2828
Publisher: Academic Press
DOI: 10.1016/j.yjmcc.2020.10.008

Stimulating pro-reparative immune responses to prevent adverse cardiac remodelling: consensus document from the joint 2019 meeting of the ESC Working Groups of cellular biology of the heart and myocardial function (opens in new window)

Author(s): Sabine Steffens, Sophie Van Linthout, Joost P G Sluijter, Carlo Gabriele Tocchetti, Thomas Thum, Rosalinda Madonna
Published in: Cardiovascular Research, Issue 116/11, 2020, Page(s) 1850-1862, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvaa137

Non-coding RNAs: emerging players in cardiomyocyte proliferation and cardiac regeneration (opens in new window)

Author(s): Naisam Abbas, Filippo Perbellini, Thomas Thum
Published in: Basic Research in Cardiology, Issue 115/5, 2020, ISSN 0300-8428
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00395-020-0816-0

miR-212/132 Cluster Modulation Prevents Doxorubicin-Mediated Atrophy and Cardiotoxicity (opens in new window)

Author(s): Shashi Kumar Gupta, Ankita Garg, Petros Avramopoulos, Stefan Engelhardt, Katrin Streckfuss-Bömeke, Sandor Batkai, Thomas Thum
Published in: Molecular Therapy, Issue 27/1, 2019, Page(s) 17-28, ISSN 1525-0016
Publisher: Nature Publishing Group
DOI: 10.1016/j.ymthe.2018.11.004

Circulating Long Noncoding RNA LIPCAR Predicts Heart Failure Outcomes in Patients Without Chronic Kidney Disease (opens in new window)

Author(s): Laura Santer, Begoña López, Susana Ravassa, Christian Baer, Isabelle Riedel, Shambhabi Chatterjee, María U. Moreno, Arantxa González, Ramón Querejeta, Florence Pinet, Thomas Thum, Javier Díez
Published in: Hypertension, Issue 73/4, 2019, Page(s) 820-828, ISSN 0194-911X
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/hypertensionaha.118.12261

TIP 30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation (opens in new window)

Author(s): Andrea Grund, Malgorzata Szaroszyk, Mortimer Korf‐Klingebiel, Mona Malek Mohammadi, Felix A Trogisch, Ulrike Schrameck, Anna Gigina, Christopher Tiedje, Matthias Gaestel, Theresia Kraft, Jan Hegermann, Sandor Batkai, Thomas Thum, Andreas Perrot, Cris dos Remedios, Eva Riechert, Mirko Völkers, Shirin Doroudgar, Andreas Jungmann, Ralf Bauer, Xiaoke Yin, Manuel Mayr, Kai C Wollert, Andreas Pich, H
Published in: EMBO Molecular Medicine, Issue 11/10, 2019, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201810018

Complex roads from genotype to phenotype in dilated cardiomyopathy: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology (opens in new window)

Author(s): Antoine Bondue, Eloisa Arbustini, Anna Bianco, Michele Ciccarelli, Dana Dawson, Matteo De Rosa, Nazha Hamdani, Denise Hilfiker-Kleiner, Benjamin Meder, Adelino F Leite-Moreira, Thomas Thum, Carlo G Tocchetti, Gilda Varricchi, Jolanda Van der Velden, Roddy Walsh, Stephane Heymans
Published in: Cardiovascular Research, Issue 114/10, 2018, Page(s) 1287-1303, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvy122

Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts (opens in new window)

Author(s): Federica De Majo, Jana-Charlotte Hegenbarth, Frank Rühle, Christian Bär, Thomas Thum, Martine de Boer, Dirk J. Duncker, Blanche Schroen, Anne-Sophie Armand, Monika Stoll, Leon J. De Windt
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-65115-9

Therapeutic and Diagnostic Translation of Extracellular Vesicles in Cardiovascular Diseases (opens in new window)

Author(s): Susmita Sahoo, Marta Adamiak, Prabhu Mathiyalagan, Franziska Kenneweg, Sabine Kafert-Kasting, Thomas Thum
Published in: Circulation, Issue 143/14, 2021, Page(s) 1426-1449, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.120.049254

Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis (opens in new window)

Author(s): Franziska Kenneweg, Claudia Bang, Ke Xiao, Chantal M. Boulanger, Xavier Loyer, Stephane Mazlan, Blanche Schroen, Steffie Hermans-Beijnsberger, Ariana Foinquinos, Marc N. Hirt, Thomas Eschenhagen, Sandra Funcke, Stevan Stojanovic, Celina Genschel, Katharina Schimmel, Annette Just, Angelika Pfanne, Kristian Scherf, Susann Dehmel, Stella M. Raemon-Buettner, Jan Fiedler, Thomas Thum
Published in: Molecular Therapy - Nucleic Acids, Issue 18, 2019, Page(s) 363-374, ISSN 2162-2531
Publisher: Nature Publishing Group
DOI: 10.1016/j.omtn.2019.09.003

Non‐coding RNAs: key players in cardiac disease (opens in new window)

Author(s): Fabian Philipp Kreutzer, Jan Fiedler, Thomas Thum
Published in: The Journal of Physiology, Issue 598/14, 2020, Page(s) 2995-3003, ISSN 0022-3751
Publisher: Blackwell Publishing Inc.
DOI: 10.1113/jp278131

SARS-CoV-2 receptor ACE2 expression in the human heart: cause of a post-pandemic wave of heart failure? (opens in new window)

Author(s): Thomas Thum
Published in: European Heart Journal, Issue 41/19, 2020, Page(s) 1807-1809, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehaa410

Studying Interactions between 2’-O-Me-Modified Inhibitors and MicroRNAs Utilizing Microscale Thermophoresis (opens in new window)

Author(s): Markus Herkt, Sandor Batkai, Thomas Thum
Published in: Molecular Therapy - Nucleic Acids, Issue 18, 2019, Page(s) 259-268, ISSN 2162-2531
Publisher: Nature Publishing Group
DOI: 10.1016/j.omtn.2019.08.019

Blood-based protein profiling identifies serum protein c-KIT as a novel biomarker for hypertrophic cardiomyopathy (opens in new window)

Author(s): Kristina Sonnenschein, Jan Fiedler, David de Gonzalo-Calvo, Ke Xiao, Angelika Pfanne, Annette Just, Carolin Zwadlo, Samira Soltani, Udo Bavendiek, Theresia Kraft, Cristobal Dos Remedios, Serghei Cebotari, Johann Bauersachs, Thomas Thum
Published in: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-80868-z

Inhibition of the Cardiac Fibroblast–Enriched lncRNA Meg3 Prevents Cardiac Fibrosis and Diastolic DysfunctionNovelty and Significance (opens in new window)

Author(s): Maria-Teresa Piccoli, Shashi Kumar Gupta, Janika Viereck, Ariana Foinquinos, Sabine Samolovac, Freya Luise Kramer, Ankita Garg, Janet Remke, Karina Zimmer, Sandor Batkai, Thomas Thum
Published in: Circulation Research, Issue 121/5, 2017, Page(s) 575-583, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.117.310624

Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling (opens in new window)

Author(s): Yassine Sassi, Petros Avramopoulos, Deepak Ramanujam, Laurenz Grüter, Stanislas Werfel, Simon Giosele, Andreas-David Brunner, Dena Esfandyari, Aikaterini S. Papadopoulou, Bart De Strooper, Norbert Hübner, Regalla Kumarswamy, Thomas Thum, Xiaoke Yin, Manuel Mayr, Bernhard Laggerbauer, Stefan Engelhardt
Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-01737-4

Circulating microRNA-132 levels improve risk prediction for heart failure hospitalization in patients with chronic heart failure (opens in new window)

Author(s): Serge Masson, Sandor Batkai, Julia Beermann, Christian Bär, Angelika Pfanne, Sabrina Thum, Michela Magnoli, Giovanna Balconi, Gian Luigi Nicolosi, Luigi Tavazzi, Roberto Latini, Thomas Thum
Published in: European Journal of Heart Failure, 2017, ISSN 1388-9842
Publisher: Elsevier BV
DOI: 10.1002/ejhf.961

Circulating Noncoding RNAs as Biomarkers of Cardiovascular Disease and Injury (opens in new window)

Author(s): Janika Viereck, Thomas Thum
Published in: Circulation Research, Issue 120/2, 2017, Page(s) 381-399, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.116.308434

Quaking Inhibits Doxorubicin-Mediated Cardiotoxicity Through Regulation of Cardiac Circular RNA ExpressionNovelty and Significance (opens in new window)

Author(s): Shashi Kumar Gupta, Ankita Garg, Christian Bär, Shambhabi Chatterjee, Ariana Foinquinos, Hendrik Milting, Katrin Streckfuß-Bömeke, Jan Fiedler, Thomas Thum
Published in: Circulation Research, Issue 122/2, 2018, Page(s) 246-254, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.117.311335

A large shRNA library approach identifies lncRNA Ntep as an essential regulator of cell proliferation (opens in new window)

Author(s): Julia Beermann, Dominique Kirste, Katharina Iwanov, Dongchao Lu, Felix Kleemiß, Regalla Kumarswamy, Katharina Schimmel, Christian Bär, Thomas Thum
Published in: Cell Death and Differentiation, Issue 25/2, 2017, Page(s) 307-318, ISSN 1350-9047
Publisher: Nature Publishing Group
DOI: 10.1038/cdd.2017.158

Nichtkodierende RNA (opens in new window)

Author(s): A. Bührke, C. Bär, T. Thum
Published in: Herz, 2017, ISSN 0340-9937
Publisher: Urban und Vogel Medien und Medizin Verlagsgesellschaft mbH
DOI: 10.1007/s00059-017-4660-4

Changing Direction (opens in new window)

Author(s): Christian Bär, Thomas Thum
Published in: Circulation Research, Issue 120/9, 2017, Page(s) 1393-1395, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.116.310316

Linc- ing the Noncoding Genome to Heart Function: Beating Hypertrophy (opens in new window)

Author(s): Shambhabi Chatterjee, Christian Bär, Thomas Thum
Published in: Trends in Molecular Medicine, Issue 23/7, 2017, Page(s) 577-579, ISSN 1471-4914
Publisher: Elsevier BV
DOI: 10.1016/j.molmed.2017.05.007

Exosomal MicroRNAs Released by Pediatric Cardiac Progenitor Cells (opens in new window)

Author(s): Ke Xiao, Thomas Thum
Published in: Circulation Research, Issue 120/4, 2017, Page(s) 607-609, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.117.310443

Long Noncoding RNAs in Pathological Cardiac Remodeling (opens in new window)

Author(s): Janika Viereck, Thomas Thum
Published in: Circulation Research, Issue 120/2, 2017, Page(s) 262-264, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.116.310174

Circular RNAs in heart failure (opens in new window)

Author(s): Yvan Devaux, Esther E. Creemers, Reinier A. Boon, Stanislas Werfel, Thomas Thum, Stefan Engelhardt, Stefanie Dimmeler, Iain Squire
Published in: European Journal of Heart Failure, Issue 19/6, 2017, Page(s) 701-709, ISSN 1388-9842
Publisher: Elsevier BV
DOI: 10.1002/ejhf.801

A long way for microRNAs to become meaningful prognostic biomarkers (opens in new window)

Author(s): Christian Bär, Thomas Thum
Published in: European Journal of Heart Failure, 2017, ISSN 1388-9842
Publisher: Elsevier BV
DOI: 10.1002/ejhf.1036

Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart (opens in new window)

Author(s): Cinzia Perrino, Albert-Laszló Barabási, Gianluigi Condorelli, Sean Michael Davidson, Leon De Windt, Stefanie Dimmeler, Felix Benedikt Engel, Derek John Hausenloy, Joseph Addison Hill, Linda Wilhelmina Van Laake, Sandrine Lecour, Jonathan Leor, Rosalinda Madonna, Manuel Mayr, Fabrice Prunier, Joost Petrus Geradus Sluijter, Rainer Schulz, Thomas Thum, Kirsti Ytrehus, Péter Ferdinandy
Published in: Cardiovascular Research, Issue 113/7, 2017, Page(s) 725-736, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvx070

Circulating Long Noncoding RNAs in Personalized Medicine (opens in new window)

Author(s): David de Gonzalo-Calvo, Franziska Kenneweg, Claudia Bang, Rocío Toro, Rutger W. van der Meer, Luuk J. Rijzewijk, Johannes W.A. Smit, Hildo J. Lamb, Vicenta Llorente-Cortes, Thomas Thum
Published in: Journal of the American College of Cardiology, Issue 68/25, 2016, Page(s) 2914-2916, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2016.10.014

Long noncoding RNA Chast promotes cardiac remodeling (opens in new window)

Author(s): J. Viereck, R. Kumarswamy, A. Foinquinos, K. Xiao, P. Avramopoulos, M. Kunz, M. Dittrich, T. Maetzig, K. Zimmer, J. Remke, A. Just, J. Fendrich, K. Scherf, E. Bolesani, A. Schambach, F. Weidemann, R. Zweigerdt, L. J. de Windt, S. Engelhardt, T. Dandekar, S. Batkai, T. Thum
Published in: Science Translational Medicine, Issue 8/326, 2016, Page(s) 326ra22-326ra22, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aaf1475

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial FibrillationClinical Perspective (opens in new window)

Author(s): Javier Barallobre-Barreiro, Shashi K. Gupta, Anna Zoccarato, Rika Kitazume-Taneike, Marika Fava, Xiaoke Yin, Tessa Werner, Marc N. Hirt, Anna Zampetaki, Alessandro Viviano, Mei Chong, Marshall Bern, Antonios Kourliouros, Nieves Domenech, Peter Willeit, Ajay M. Shah, Marjan Jahangiri, Liliana Schaefer, Jens W. Fischer, Renato V. Iozzo, Rosa Viner, Thomas Thum, Joerg Heineke, Antoine Kichler, Kinya
Published in: Circulation, Issue 134/11, 2016, Page(s) 817-832, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCULATIONAHA.115.016423

Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart FailureNovelty and Significance (opens in new window)

Author(s): Sandra C. Mayer, Ralf Gilsbach, Sebastian Preissl, Elsa Beatriz Monroy Ordonez, Tilman Schnick, Nadine Beetz, Achim Lother, Carolin Rommel, Hannah Ihle, Heiko Bugger, Frank Rühle, Andrea Schrepper, Michael Schwarzer, Claudia Heilmann, Ulrike Bönisch, Shashi Kumar Gupta, Jochen Wilpert, Oliver Kretz, Dominik von Elverfeldt, Joachim Orth, Klaus Aktories, Friedhelm Beyersdorf, Christoph Bode, Brigi
Published in: Circulation Research, Issue 117/7, 2015, Page(s) 622-633, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCRESAHA.115.306721

Non-coding RNAs as modulators of the cardiac fibroblast phenotype (opens in new window)

Author(s): Maria-Teresa Piccoli, Christian Bär, Thomas Thum
Published in: Journal of Molecular and Cellular Cardiology, Issue 92, 2016, Page(s) 75-81, ISSN 0022-2828
Publisher: Academic Press
DOI: 10.1016/j.yjmcc.2015.12.023

Circulating long-non coding RNAs as biomarkers of left ventricular diastolic function and remodelling in patients with well-controlled type 2 diabetes (opens in new window)

Author(s): D. de Gonzalo-Calvo, F. Kenneweg, C. Bang, R. Toro, R. W. van der Meer, L. J. Rijzewijk, J. W. Smit, H. J. Lamb, V. Llorente-Cortes, T. Thum
Published in: Scientific Reports, Issue 6, 2016, Page(s) 37354, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/srep37354

Antiageing concepts and cardiovascular disease (opens in new window)

Author(s): Thomas Thum
Published in: European Heart Journal, Issue 36/48, 2015, Page(s) 3435-3436, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehv412

Regulator of G-Protein Signaling 5 Prevents Smooth Muscle Cell Proliferation and Attenuates Neointima FormationSignificance (opens in new window)

Author(s): Jan-Marcus Daniel, André Prock, Jochen Dutzmann, Kristina Sonnenschein, Thomas Thum, Johann Bauersachs, Daniel G. Sedding
Published in: Arteriosclerosis, Thrombosis, and Vascular Biology, Issue 36/2, 2016, Page(s) 317-327, ISSN 1079-5642
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/ATVBAHA.115.305974

Non-coding RNAs as orchestrators of autophagic processes (opens in new window)

Author(s): Shashi Kumar Gupta, Thomas Thum
Published in: Journal of Molecular and Cellular Cardiology, Issue 95, 2016, Page(s) 26-30, ISSN 0022-2828
Publisher: Academic Press
DOI: 10.1016/j.yjmcc.2015.11.012

Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and Therapy (opens in new window)

Author(s): Christian Bär, Shambhabi Chatterjee, Thomas Thum
Published in: Circulation, Issue 134/19, 2016, Page(s) 1484-1499, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCULATIONAHA.116.023686

Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches (opens in new window)

Author(s): Julia Beermann, Maria-Teresa Piccoli, Janika Viereck, Thomas Thum
Published in: Physiological Reviews, Issue 96/4, 2016, Page(s) 1297-1325, ISSN 0031-9333
Publisher: American Physiological Society
DOI: 10.1152/physrev.00041.2015

Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction (opens in new window)

Author(s): Shashi Kumar Gupta, Ariana Foinquinos, Sabrina Thum, Janet Remke, Karina Zimmer, Christophe Bauters, Pascal de Groote, Reinier A. Boon, Leon J. de Windt, Sebastian Preissl, Lutz Hein, Sandor Batkai, Florence Pinet, Thomas Thum
Published in: Journal of the American College of Cardiology, Issue 68/14, 2016, Page(s) 1557-1571, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2016.07.739

A comprehensive method protocol for annotation and integrated functional understanding of lncRNAs (opens in new window)

Author(s): Meik Kunz, Beat Wolf, Maximilian Fuchs, Jan Christoph, Ke Xiao, Thomas Thum, David Atlan, Hans-Ulrich Prokosch, Thomas Dandekar
Published in: Briefings in Bioinformatics, Issue 21/4, 2019, Page(s) 1391-1396, ISSN 1477-4054
Publisher: Oxford Academic
DOI: 10.1093/bib/bbz066

CircSlc8a1, breaking a vicious circle in cardiac hypertrophy (opens in new window)

Author(s): Christopher Jahn, Christian Bär, Thomas Thum
Published in: Cardiovascular Research, Issue 115/14, 2019, Page(s) 1946-1947, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvz147

Serum circular RNAs act as blood-based biomarkers for hypertrophic obstructive cardiomyopathy (opens in new window)

Author(s): Kristina Sonnenschein, Adriana Luisa Wilczek, David de Gonzalo-Calvo, Angelika Pfanne, Anselm Arthur Derda, Carolin Zwadlo, Udo Bavendiek, Johann Bauersachs, Jan Fiedler, Thomas Thum
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-56617-2

Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction (opens in new window)

Author(s): Katharina Schimmel, Mira Jung, Ariana Foinquinos, Gorka San José, Javier Beaumont, Katharina Bock, Lea Grote-Levi, Ke Xiao, Christian Bär, Angelika Pfanne, Annette Just, Karina Zimmer, Soeun Ngoy, Begoña López, Susana Ravassa, Sabine Samolovac, Heike Janssen-Peters, Janet Remke, Kristian Scherf, Seema Dangwal, Maria-Teresa Piccoli, Felix Kleemiss, Fabian Philipp Kreutzer, Franziska Kenneweg, J
Published in: Circulation, Issue 141/9, 2020, Page(s) 751-767, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.119.042559

Preclinical and Clinical Development of Noncoding RNA Therapeutics for Cardiovascular Disease (opens in new window)

Author(s): Cheng-Kai Huang, Sabine Kafert-Kasting, Thomas Thum
Published in: Circulation Research, Issue 126/5, 2020, Page(s) 663-678, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.315856

Telomerase therapy attenuates cardiotoxic effects of doxorubicin (opens in new window)

Author(s): Shambhabi Chatterjee, Teresa Hofer, Alessia Costa, Dongchao Lu, Sandor Batkai, Shashi Kumar Gupta, Emiliano Bolesani, Robert Zweigerdt, Diego Megias, Katrin Streckfuss-Bömeke, Christina Brandenberger, Thomas Thum, Christian Bär
Published in: Molecular Therapy, 2021, ISSN 1525-0016
Publisher: Nature Publishing Group
DOI: 10.1016/j.ymthe.2020.12.035

Pharmacokinetic Studies of Antisense Oligonucleotides Using MALDI-TOF Mass Spectrometry (opens in new window)

Author(s): Markus Herkt, Ariana Foinquinos, Sandor Batkai, Thomas Thum, Andreas Pich
Published in: Frontiers in Pharmacology, Issue 11, 2020, ISSN 1663-9812
Publisher: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.00220

Translational Opportunities and Challenges of Long Noncoding RNAs in Cardiac Regeneration (opens in new window)

Author(s): Thomas Thum
Published in: Journal of the American College of Cardiology, Issue 72/5, 2018, Page(s) 551-552, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2018.05.039

Inflammatory cells and their non-coding RNAs as targets for treating myocardial infarction (opens in new window)

Author(s): Mira Jung, Michael Dodsworth, Thomas Thum
Published in: Basic Research in Cardiology, Issue 114/1, 2019, ISSN 0300-8428
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00395-018-0712-z

The Long Non-coding RNA Cyrano Is Dispensable for Pluripotency of Murine and Human Pluripotent Stem Cells (opens in new window)

Author(s): Hannah J. Hunkler, Jeannine Hoepfner, Cheng-Kai Huang, Shambhabi Chatterjee, Monica Jara-Avaca, Ina Gruh, Emiliano Bolesani, Robert Zweigerdt, Thomas Thum, Christian Bär
Published in: Stem Cell Reports, Issue 15/1, 2020, Page(s) 13-21, ISSN 2213-6711
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2020.05.011

Resident cardiac macrophages: crucial modulators of cardiac (patho)physiology (opens in new window)

Author(s): M. Sansonetti, F. J. G. Waleczek, M. Jung, T. Thum, F. Perbellini
Published in: Basic Research in Cardiology, Issue 115/6, 2020, ISSN 0300-8428
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00395-020-00836-6

Intellectual Property Rights

THE INCRNA MEG3 FOR THERAPY AND DIAGNOSIS OF CARDIAC REMODELLING

Application/Publication number: 17 722704
Date: 2017-04-26
Applicant(s): MEDIZINISCHE HOCHSCHULE HANNOVER

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