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CORDIS

Antibacterial (Nano)medicines Development

Ziel

Despite the investment of billions of euros, there has been an inexorable decline in the discovery of new antibiotics over the last decades. In this individual fellowship (IF) application we propose a strategy to develop bacterial histidine-kinase (HK) inhibitors targeted at the catalytic and ATP-biding domain (CA) as novel broad-spectrum antibacterial (nano)medicines. Furthermore, putative mechanism of resistance to HK inhibitors and known antibiotics will be studied and novel antibacterial drug targets will be identified by using transposon insertion mutant libraries (Tn-libraries) to identify mutations involved in intrinsic resistance to antibiotics and/or leading to increased sensitivity to existing antibiotics in multi-drug resistant (MDR) strains.

Programm/Programme

Thema/Themen

Finanzierungsplan

MSCA-IF-EF-ST - Standard EF

Alle im Rahmen dieses Finanzierungsinstruments finanzierten Projekte anzeigen

Aufforderung zur Vorschlagseinreichung

(öffnet in neuem Fenster) H2020-MSCA-IF-2014

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Koordinator

WAGENINGEN UNIVERSITY
Netto-EU-Beitrag
€ 165 598,80
Adresse
DROEVENDAALSESTEEG 4
6708 PB Wageningen
Niederlande
Region
Oost-Nederland Gelderland Veluwe
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 165 598,80