Publications Peer reviewed articles (16) Coordinated roles of SLX4 and MutSβ in DNA repair and the maintenance of genome stability Author(s): Young, S. J. West, S. C. Published in: Crit. Rev. Biochem. Mol. Biol., Issue 56, 2021, Page(s) 157-177, ISSN 1549-7798 Publisher: Taylor and Francis DOI: 10.1080/10409238.2021.1881433 Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors Author(s): Fugger, K. Bajrami, I. Silva Dos Santos, M. Young, S. J. Kunzelmann, S. Kelly, G. Hewitt, G. Patel, H. Goldstone, R. Carell, T. Boulton, S. J. MacRae, J. Taylor, I. A. West, S. C. Published in: Science, Issue 372, 2021, Page(s) 156-165, ISSN 1095-9203 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.abb4542 Defective ALC1 nucleosome remodelling confers PARPi sensitivity and synthetic lethality with HRD Author(s): Hewitt, G. Borel, V. Segura-Bayona, S. Takaki, T. Ruis, P. Bellelli, R. Lehmann, L. C. Sommerova, L. Vancevska, A. Tomas-Loba, A. Zhu, K. Cooper, C. Fugger, K. Patel, H. Goldstone, R. Schneider-Luftman, D. Herbert, E. Stamp, G. Brough, R. Pettitt, S. Lord, C. J. West, S. C. Ahel, I. Ahel, D. Chapman, J. R. Deindl, S. Boulton, S. J. Published in: Molecular Cell, Issue 81, 2021, Page(s) 767-783, ISSN 1097-4164 Publisher: Cell Press DOI: 10.1016/j.molcel.2020.12.006 Tackling PARP inhibitor resistance Author(s): Fugger, K. Hewitt, G. West, S. C. Boulton, S. J. Published in: Trends Cancer, Issue 12, 2021, Page(s) 1102-1118, ISSN 2405-8025 Publisher: Cell Press DOI: 10.1016/j.trecan.2021.08.007 Integrated genome and transcriptome analyses reveal the mechanism of genome instability in ataxia with oculomotor apraxia 2 Author(s): Kanagaraj, R. Mitter, R. Kantidakis, T. Edwards, M.M. Benitez, A. Chakravarty, P. Fu, B. Becherel, O. J. Yang, F. Lavin, M.F. Koren, A. Stewart, A. West, S.C. Published in: Proc. Natl. Acad. Sci. USA, Issue 119, 2022, Page(s) e2114314119, ISSN 1091-6490 Publisher: National Academy of Sciences DOI: 10.1073/pnas.2114314119 Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations Author(s): Ying Wai Chan, Kasper Fugger, Stephen C. West Published in: Nature Cell Biology, Issue 20/1, 2018, Page(s) 92-103, ISSN 1465-7392 Publisher: Nature Publishing Group DOI: 10.1038/s41556-017-0011-1 Genome Instability as a Consequence of Defects in the Resolution of Recombination Intermediates Author(s): Stephen C. West, Ying Wai Chan Published in: Cold Spring Harbor Symposia on Quantitative Biology, Issue 82, 2018, Page(s) 034256, ISSN 0091-7451 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/sqb.2017.82.034256 SMX makes the cut in genome stability Author(s): Haley D.M. Wyatt, Stephen C. West Published in: Oncotarget, Issue 8/61, 2017, ISSN 1949-2553 Publisher: Impact Journals DOI: 10.18632/oncotarget.22420 The SMX DNA Repair Tri-nuclease Author(s): Haley D.M. Wyatt, Rob C. Laister, Stephen R. Martin, Cheryl H. Arrowsmith, Stephen C. West Published in: Molecular Cell, Issue 65/5, 2017, Page(s) 848-860.e11, ISSN 1097-2765 Publisher: Cell Press DOI: 10.1016/j.molcel.2017.01.031 A new class of ultrafine anaphase bridges generated by homologous recombination Author(s): Ying Wai Chan, Stephen C. West Published in: Cell Cycle, 2018, Page(s) 1-9, ISSN 1538-4101 Publisher: Landes Bioscience DOI: 10.1080/15384101.2018.1515555 Resolution of single and double Holliday junction recombination intermediates by GEN1 Author(s): Shah Punatar, R. Martin, M. J. Wyatt, H. D. Chan, Y. W. West, S. C. Published in: Proc Natl Acad Sci U S A, Issue 114, 2017, Page(s) 443-450, ISSN 0027-8424 Publisher: National Academy of Sciences DOI: 10.1073/pnas.1619790114 Resolution of Recombination Intermediates: Mechanisms and Regulation Author(s): Stephen C. West, Miguel G. Blanco, Ying Wai Chan, Joao Matos, Shriparna Sarbajna, Haley D.M. Wyatt Published in: Cold Spring Harbor Symposia on Quantitative Biology, Issue 80, 2015, Page(s) 103-109, ISSN 0091-7451 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/sqb.2015.80.027649 Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis Author(s): Kotynkova, K. Su, K. C. West, S. C. Petronczki, M. Published in: Cell Reports, Issue 17, 2016, Page(s) 2672-2686, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2016.11.029 GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism Author(s): Ying Wai Chan, Stephen West Published in: Nucleic Acids Research, Issue 43/22, 2015, Page(s) 10882-10892, ISSN 0305-1048 Publisher: Oxford University Press DOI: 10.1093/nar/gkv1207 MutSβ Stimulates Holliday Junction Resolution by the SMX Complex Author(s): Young, S. J. Sebald, M. Shah Punatar, R. Larin, M. Masino, L. Rodrigo-Brenni, M. C. Liang, C. C. West, S. C. Published in: Cell Reports, Issue 33, 2020, Page(s) 108289, ISSN 2211-1247 Publisher: Cell Press DOI: 10.1016/j.celrep.2020.108289 Repeat expansions confer WRN dependence in microsatellite-unstable cancers Author(s): van Wietmarschen, Niek Sridharan, Sriram Nathan, William J. Tubbs, Anthony Chan, Edmond M. Callen, Elsa Wu, Wei Belinky, Frida Tripathi, Veenu Wong, Nancy Foster, Kyla Noorbakhsh, Javad Garimella, Kiran Cruz-Migoni, Abimael Sommers, Joshua A. Huang, Yongqing Borah, Ashir A. Smith, Jonathan T. Kalfon, Jeremie Kesten, Nikolas Fugger, Kasper Walker, Robert L. Dolzhenko, Egor Eberle, Michael A. Haywar Published in: Nature, Issue 586, 2020, Page(s) 292-298, ISSN 1476-4687 Publisher: MacMillan DOI: 10.1038/s41586-020-2769-8 Book chapters (3) Preparation and resolution of Holliday junction DNA recombination intermediates Author(s): Rajvee Shah Punatar, Stephen C. West Published in: Methods in Enzymology, Issue 600, 2018, Page(s) 569-590 Publisher: Elsevier DOI: 10.1016/bs.mie.2017.11.022 GEN1 endonuclease: Purification and nuclease assays Author(s): Ying Wai Chan, Stephen C. West Published in: Methods in Enzymology, Issue 600, 2018, Page(s) 527-542 Publisher: Elsevier DOI: 10.1016/bs.mie.2017.11.020 Analysis of Structure-Selective Endonuclease Activities From Yeast and Human Extracts Author(s): Joao Matos, Stephen C. West Published in: Methods in Enzymology, Issue 591, 2017, Page(s) 271-286 Publisher: Elsevier DOI: 10.1016/bs.mie.2017.03.005 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
