DNA strand break repair and links to human disease

Publikacje

Coordinated roles of SLX4 and MutSβ in DNA repair and the maintenance of genome stability

Autorzy: Young, S. J. West, S. C.
Opublikowane w: Crit. Rev. Biochem. Mol. Biol., Numer 56, 2021, Strona(/y) 157-177, ISSN 1549-7798
Wydawca: Taylor and Francis
DOI: 10.1080/10409238.2021.1881433

Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors

Autorzy: Fugger, K. Bajrami, I. Silva Dos Santos, M. Young, S. J. Kunzelmann, S. Kelly, G. Hewitt, G. Patel, H. Goldstone, R. Carell, T. Boulton, S. J. MacRae, J. Taylor, I. A. West, S. C.
Opublikowane w: Science, Numer 372, 2021, Strona(/y) 156-165, ISSN 1095-9203
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.abb4542

Defective ALC1 nucleosome remodelling confers PARPi sensitivity and synthetic lethality with HRD

Autorzy: Hewitt, G. Borel, V. Segura-Bayona, S. Takaki, T. Ruis, P. Bellelli, R. Lehmann, L. C. Sommerova, L. Vancevska, A. Tomas-Loba, A. Zhu, K. Cooper, C. Fugger, K. Patel, H. Goldstone, R. Schneider-Luftman, D. Herbert, E. Stamp, G. Brough, R. Pettitt, S. Lord, C. J. West, S. C. Ahel, I. Ahel, D. Chapman, J. R. Deindl, S. Boulton, S. J.
Opublikowane w: Molecular Cell, Numer 81, 2021, Strona(/y) 767-783, ISSN 1097-4164
Wydawca: Cell Press
DOI: 10.1016/j.molcel.2020.12.006

Tackling PARP inhibitor resistance

Autorzy: Fugger, K. Hewitt, G. West, S. C. Boulton, S. J.
Opublikowane w: Trends Cancer, Numer 12, 2021, Strona(/y) 1102-1118, ISSN 2405-8025
Wydawca: Cell Press
DOI: 10.1016/j.trecan.2021.08.007

Integrated genome and transcriptome analyses reveal the mechanism of genome instability in ataxia with oculomotor apraxia 2

Autorzy: Kanagaraj, R. Mitter, R. Kantidakis, T. Edwards, M.M. Benitez, A. Chakravarty, P. Fu, B. Becherel, O. J. Yang, F. Lavin, M.F. Koren, A. Stewart, A. West, S.C.
Opublikowane w: Proc. Natl. Acad. Sci. USA, Numer 119, 2022, Strona(/y) e2114314119, ISSN 1091-6490
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2114314119

Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations

Autorzy: Ying Wai Chan, Kasper Fugger, Stephen C. West
Opublikowane w: Nature Cell Biology, Numer 20/1, 2018, Strona(/y) 92-103, ISSN 1465-7392
Wydawca: Nature Publishing Group
DOI: 10.1038/s41556-017-0011-1

Genome Instability as a Consequence of Defects in the Resolution of Recombination Intermediates

Autorzy: Stephen C. West, Ying Wai Chan
Opublikowane w: Cold Spring Harbor Symposia on Quantitative Biology, Numer 82, 2018, Strona(/y) 034256, ISSN 0091-7451
Wydawca: Cold Spring Harbor Laboratory Press
DOI: 10.1101/sqb.2017.82.034256

SMX makes the cut in genome stability

Autorzy: Haley D.M. Wyatt, Stephen C. West
Opublikowane w: Oncotarget, Numer 8/61, 2017, ISSN 1949-2553
Wydawca: Impact Journals
DOI: 10.18632/oncotarget.22420

The SMX DNA Repair Tri-nuclease

Autorzy: Haley D.M. Wyatt, Rob C. Laister, Stephen R. Martin, Cheryl H. Arrowsmith, Stephen C. West
Opublikowane w: Molecular Cell, Numer 65/5, 2017, Strona(/y) 848-860.e11, ISSN 1097-2765
Wydawca: Cell Press
DOI: 10.1016/j.molcel.2017.01.031

A new class of ultrafine anaphase bridges generated by homologous recombination

Autorzy: Ying Wai Chan, Stephen C. West
Opublikowane w: Cell Cycle, 2018, Strona(/y) 1-9, ISSN 1538-4101
Wydawca: Landes Bioscience
DOI: 10.1080/15384101.2018.1515555

Resolution of single and double Holliday junction recombination intermediates by GEN1

Autorzy: Shah Punatar, R. Martin, M. J. Wyatt, H. D. Chan, Y. W. West, S. C.
Opublikowane w: Proc Natl Acad Sci U S A, Numer 114, 2017, Strona(/y) 443-450, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1619790114

Resolution of Recombination Intermediates: Mechanisms and Regulation

Autorzy: Stephen C. West, Miguel G. Blanco, Ying Wai Chan, Joao Matos, Shriparna Sarbajna, Haley D.M. Wyatt
Opublikowane w: Cold Spring Harbor Symposia on Quantitative Biology, Numer 80, 2015, Strona(/y) 103-109, ISSN 0091-7451
Wydawca: Cold Spring Harbor Laboratory Press
DOI: 10.1101/sqb.2015.80.027649

Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis

Autorzy: Kotynkova, K. Su, K. C. West, S. C. Petronczki, M.
Opublikowane w: Cell Reports, Numer 17, 2016, Strona(/y) 2672-2686, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2016.11.029

GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism

Autorzy: Ying Wai Chan, Stephen West
Opublikowane w: Nucleic Acids Research, Numer 43/22, 2015, Strona(/y) 10882-10892, ISSN 0305-1048
Wydawca: Oxford University Press
DOI: 10.1093/nar/gkv1207

MutSβ Stimulates Holliday Junction Resolution by the SMX Complex

Autorzy: Young, S. J. Sebald, M. Shah Punatar, R. Larin, M. Masino, L. Rodrigo-Brenni, M. C. Liang, C. C. West, S. C.
Opublikowane w: Cell Reports, Numer 33, 2020, Strona(/y) 108289, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2020.108289

Repeat expansions confer WRN dependence in microsatellite-unstable cancers

Autorzy: van Wietmarschen, Niek Sridharan, Sriram Nathan, William J. Tubbs, Anthony Chan, Edmond M. Callen, Elsa Wu, Wei Belinky, Frida Tripathi, Veenu Wong, Nancy Foster, Kyla Noorbakhsh, Javad Garimella, Kiran Cruz-Migoni, Abimael Sommers, Joshua A. Huang, Yongqing Borah, Ashir A. Smith, Jonathan T. Kalfon, Jeremie Kesten, Nikolas Fugger, Kasper Walker, Robert L. Dolzhenko, Egor Eberle, Michael A. Haywar
Opublikowane w: Nature, Numer 586, 2020, Strona(/y) 292-298, ISSN 1476-4687
Wydawca: MacMillan
DOI: 10.1038/s41586-020-2769-8

Preparation and resolution of Holliday junction DNA recombination intermediates

Autorzy: Rajvee Shah Punatar, Stephen C. West
Opublikowane w: Methods in Enzymology, Numer 600, 2018, Strona(/y) 569-590
Wydawca: Elsevier
DOI: 10.1016/bs.mie.2017.11.022

GEN1 endonuclease: Purification and nuclease assays

Autorzy: Ying Wai Chan, Stephen C. West
Opublikowane w: Methods in Enzymology, Numer 600, 2018, Strona(/y) 527-542
Wydawca: Elsevier
DOI: 10.1016/bs.mie.2017.11.020

Analysis of Structure-Selective Endonuclease Activities From Yeast and Human Extracts

Autorzy: Joao Matos, Stephen C. West
Opublikowane w: Methods in Enzymology, Numer 591, 2017, Strona(/y) 271-286
Wydawca: Elsevier
DOI: 10.1016/bs.mie.2017.03.005

Wyszukiwanie danych OpenAIRE...

Publikacje

Udostępnij tę stronę

Pobierz