Regeneration of the adult zebrafish brain

Project Information

ZF-BrainReg

Grant agreement ID: 669811

DOI

10.3030/669811

Project closed

EC signature date 19 October 2015

Start date 1 January 2016

End date 31 December 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

TECHNISCHE UNIVERSITAET DRESDEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (21)

Single cell sequencing of radial glia progeny reveals the diversity of newborn neurons in the adult zebrafish brain

Author(s): Christian Lange, Fabian Rost, Anja Machate, Susanne Reinhardt, Matthias Lesche, Anke Weber, Veronika Kuscha, Andreas Dahl, Steffen Rulands, Michael Brand
Published in: Development, Issue 147/1, 2020, Page(s) dev185595, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.185595

Isthmin1, a secreted signaling protein, acts downstream of diverse embryonic patterning centers in development

Author(s): Kesavan G, Raible F, Gupta M, Machate A, Yilmaz D, Brand M
Published in: Cell Tissue Research, Issue 383(3), 2020, Page(s) 987-1002, ISSN 0302-766X
Publisher: Springer Verlag
DOI: 10.1007/s00441-020-03318-2

Electrophysiological Properties of Adult Zebrafish Oligodendrocyte Progenitor Cells

Author(s): Vasiliki Tsata, Volker Kroehne, Susanne Reinhardt, Ali El-Armouche, Michael Brand, Michael Wagner, Michell M. Reimer
Published in: Frontiers in Cellular Neuroscience, Issue 13, 2019, ISSN 1662-5102
Publisher: Frontiers Research Foundation
DOI: 10.3389/fncel.2019.00102

Heparan sulfate proteoglycan expression in the regenerating zebrafish fin.

Author(s): Keil S, Gupta M, Brand M, Knopf F.
Published in: Developmental Dynamics, Issue 250(9), 2021, Page(s) 1368-1380, ISSN 1058-8388
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/dvdy.321

Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain.

Author(s): Suzzi S, Ahrendt R, Hans S, Semenova SA, Chekuru A, Wirsching P, Kroehne V, Bilican S, Sayed S, Winkler S, Spieß S, Machate A, Kaslin J, Panula P, Brand M
Published in: PLoS Genetics, Issue 7(9), 2021, Page(s) e1009794, ISSN 1553-7390
Publisher: Public Library of Science
DOI: 10.1371/journal.pgen.1009794

Polyacrylamide Bead Sensors for in vivo Quantification of Cell-Scale Stress in Zebrafish Development

Author(s): N. Träber, K. Uhlmann, S. Girardo, G. Kesavan, K. Wagner, J. Friedrichs, R. Goswami, K. Bai, M. Brand, C. Werner, D. Balzani, J. Guck
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-53425-6

Cre-Controlled CRISPR mutagenesis provides fast and easy conditional gene inactivation in zebrafish.

Author(s): Stefan Hans, Daniela Zöller, Juliane Hammer, Johanna Stucke, Sandra Spieß, Gokul Kesavan, Volker Kroehne, Juan Sebastian Eguiguren, Diana Ezhkova, Andreas Petzold, Andreas Dahl, Michael Brand
Published in: nature communications, Issue 12(1), 2021, Page(s) 1125, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-21427-6

A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord.

Author(s): Tsata V, Möllmert S, Schweitzer C, Kolb J, Möckel C, Böhm B, Rosso G, Lange C, Lesche M, Hammer J, Kesavan G, Beis D, Guck J, Brand M, Wehner D
Published in: Developmental Cell, Issue 56(4), 2021, Page(s) 509-524.e9, ISSN 1534-5807
Publisher: Cell Press
DOI: 10.1016/j.devcel.2020.12.009

In Vivo Chemical Screen in Zebrafish Embryos Identifies Regulators of Hematopoiesis Using a Semiautomated Imaging Assay

Author(s): Guruchandar Arulmozhivarman, Martin Stöter, Marc Bickle, Martin Kräter, Manja Wobus, Gerhard Ehninger, Friedrich Stölzel, Michael Brand, Martin Bornhäuser, Nona Shayegi
Published in: Journal of Biomolecular Screening, Issue 21/9, 2016, Page(s) 956-964, ISSN 1087-0571
Publisher: Sage Science Press
DOI: 10.1177/1087057116644163

Role of the immune response in initiating central nervous system regeneration in vertebrates: learning from the fish

Author(s): Viktoria Bosak, Kei Murata, Oliver Bludau, Michael Brand
Published in: The International Journal of Developmental Biology, Issue 62/6-7-8, 2018, Page(s) 403-417, ISSN 0214-6282
Publisher: University of the Basque Country Press
DOI: 10.1387/IJDB.180033VB

Cre-inducible site-specific recombination in zebrafish oligodendrocytes

Author(s): Alejandro Pinzon-Olejua, Cornelia Welte, Avinash Chekuru, Viktoria Bosak, Michael Brand, Stefan Hans, Claudia A.O. Stuermer
Published in: Developmental Dynamics, Issue 246/1, 2017, Page(s) 41-49, ISSN 1058-8388
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/dvdy.24458

Targeted knock-in of CreERT2 in zebrafish using CRISPR/Cas9

Author(s): Gokul Kesavan, Juliane Hammer, Stefan Hans, Michael Brand
Published in: Cell and Tissue Research, Issue 372/1, 2018, Page(s) 41-50, ISSN 0302-766X
Publisher: Springer Verlag
DOI: 10.1007/s00441-018-2798-x

Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development

Author(s): Jonathan Henninger, Buyung Santoso, Stefan Hans, Ellen Durand, Jessica Moore, Christian Mosimann, Michael Brand, David Traver, Leonard Zon
Published in: Nature Cell Biology, Issue 19/1, 2017, Page(s) 17-27, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/ncb3444

Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: - Preclinical Validation in Human CD34+ Stem and Progenitor Cells

Author(s): Guruchandar Arulmozhivarman, Martin Kräter, Manja Wobus, Jens Friedrichs, Elham Pishali Bejestani, Katrin Müller, Katrin Lambert, Dimitra Alexopoulou, Andreas Dahl, Martin Stöter, Marc Bickle, Nona Shayegi, Jochen Hampe, Friedrich Stölzel, Michael Brand, Malte von Bonin, Martin Bornhäuser
Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-017-12360-0

Radiobiological effects and proton RBE determined by wildtype zebrafish embryos

Author(s): Emília Rita Szabó, Michael Brand, Stefan Hans, Katalin Hideghéty, Leonhard Karsch, Elisabeth Lessmann, Jörg Pawelke, Michael Schürer, Elke Beyreuther
Published in: PLOS ONE, Issue 13/11, 2018, Page(s) e0206879, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0206879

CRISPR/Cas9-Mediated Zebrafish Knock-in as a Novel Strategy to Study Midbrain-Hindbrain Boundary Development

Author(s): Gokul Kesavan, Avinash Chekuru, Anja Machate, Michael Brand
Published in: Frontiers in Neuroanatomy, Issue 11, 2017, ISSN 1662-5129
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnana.2017.00052

Immune Suppressive and Bone Inhibitory Effects of Prednisolone in Growing and Regenerating Zebrafish Tissues

Author(s): Karina Geurtzen, Aude Vernet, Andrew Freidin, Martina Rauner, Lorenz C Hofbauer, Jürgen E Schneider, Michael Brand, Franziska Knopf
Published in: Journal of Bone and Mineral Research, 2017, ISSN 0884-0431
Publisher: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3231

Distinct roles of neuroepithelial-like and radial glia-like progenitor cells in cerebellar regeneration

Author(s): Jan Kaslin, Volker Kroehne, Julia Ganz, Stefan Hans, Michael Brand
Published in: Development, Issue 144/8, 2017, Page(s) 1462-1471, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.144907

Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth

Author(s): Sumeet Pal Singh, Sharan Janjuha, Theresa Hartmann, Özge Kayisoglu, Judith Konantz, Sarah Birke, Priyanka Murawala, Ezzaldin Ahmed Alfar, Kei Murata, Anne Eugster, Naoki Tsuji, Edward R. Morrissey, Michael Brand, Nikolay Ninov
Published in: Nature Communications, Issue 8/1, 2017, Page(s)  664, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-00461-3

Cell-fate plasticity, adhesion and cell sorting complementarily establish a sharp midbrain-hindbrain boundary

Author(s): Gokul Kesavan, Anja Machate, Stefan Hans, Michael Brand
Published in: Development, Issue 147/11, 2020, Page(s) dev186882, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.186882

Zebrafish Spinal Cord Repair Is Accompanied by Transient Tissue Stiffening

Author(s): Stephanie Möllmert, Maria A. Kharlamova, Tobias Hoche, Anna V. Taubenberger, Shada Abuhattum, Veronika Kuscha, Thomas Kurth, Michael Brand, Jochen Guck
Published in: Biophysical Journal, Issue 118/2, 2020, Page(s) 448-463, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2019.10.044

Book chapters (1)

The Zebrafish Cerebellum

Author(s): Jan Kaslin, Michael Brand
Published in: Essentials of Cerebellum and Cerebellar Disorders, 2016, Page(s) 411-421
Publisher: Springer International Publishing
DOI: 10.1007/978-3-319-24551-5_56

Other (1)

Loss of lrrk2 impairs dopamine catabolism, cell proliferation, and neuronal regeneration in the zebrafish brain

Author(s): Stefano Suzzi, Reiner Ahrendt, Stefan Hans, Svetlana A. Semenova, Saygin Bilican, Shady Sayed, Sylke Winkler, Sandra Spiess, Jan Kaslin, Pertti Panula, Michael Brand
Published in: bioRxiv, Issue 140608, 2017
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/140608