Regeneration of the adult zebrafish brain

Información del proyecto

ZF-BrainReg

Identificador del acuerdo de subvención: 669811

DOI

10.3030/669811

Proyecto cerrado

Fecha de la firma de la CE 19 Octubre 2015

Fecha de inicio 1 Enero 2016

Fecha de finalización 31 Diciembre 2021

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 2 500 000,00

Aportación de la UE

€ 2 500 000,00

Coordinado por

TECHNISCHE UNIVERSITAET DRESDEN
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (21)

Single cell sequencing of radial glia progeny reveals the diversity of newborn neurons in the adult zebrafish brain

Autores: Christian Lange, Fabian Rost, Anja Machate, Susanne Reinhardt, Matthias Lesche, Anke Weber, Veronika Kuscha, Andreas Dahl, Steffen Rulands, Michael Brand
Publicado en: Development, Edición 147/1, 2020, Página(s) dev185595, ISSN 0950-1991
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dev.185595

Isthmin1, a secreted signaling protein, acts downstream of diverse embryonic patterning centers in development

Autores: Kesavan G, Raible F, Gupta M, Machate A, Yilmaz D, Brand M
Publicado en: Cell Tissue Research, Edición 383(3), 2020, Página(s) 987-1002, ISSN 0302-766X
Editor: Springer Verlag
DOI: 10.1007/s00441-020-03318-2

Electrophysiological Properties of Adult Zebrafish Oligodendrocyte Progenitor Cells

Autores: Vasiliki Tsata, Volker Kroehne, Susanne Reinhardt, Ali El-Armouche, Michael Brand, Michael Wagner, Michell M. Reimer
Publicado en: Frontiers in Cellular Neuroscience, Edición 13, 2019, ISSN 1662-5102
Editor: Frontiers Research Foundation
DOI: 10.3389/fncel.2019.00102

Heparan sulfate proteoglycan expression in the regenerating zebrafish fin.

Autores: Keil S, Gupta M, Brand M, Knopf F.
Publicado en: Developmental Dynamics, Edición 250(9), 2021, Página(s) 1368-1380, ISSN 1058-8388
Editor: John Wiley & Sons Inc.
DOI: 10.1002/dvdy.321

Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain.

Autores: Suzzi S, Ahrendt R, Hans S, Semenova SA, Chekuru A, Wirsching P, Kroehne V, Bilican S, Sayed S, Winkler S, Spieß S, Machate A, Kaslin J, Panula P, Brand M
Publicado en: PLoS Genetics, Edición 7(9), 2021, Página(s) e1009794, ISSN 1553-7390
Editor: Public Library of Science
DOI: 10.1371/journal.pgen.1009794

Polyacrylamide Bead Sensors for in vivo Quantification of Cell-Scale Stress in Zebrafish Development

Autores: N. Träber, K. Uhlmann, S. Girardo, G. Kesavan, K. Wagner, J. Friedrichs, R. Goswami, K. Bai, M. Brand, C. Werner, D. Balzani, J. Guck
Publicado en: Scientific Reports, Edición 9/1, 2019, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-53425-6

Cre-Controlled CRISPR mutagenesis provides fast and easy conditional gene inactivation in zebrafish.

Autores: Stefan Hans, Daniela Zöller, Juliane Hammer, Johanna Stucke, Sandra Spieß, Gokul Kesavan, Volker Kroehne, Juan Sebastian Eguiguren, Diana Ezhkova, Andreas Petzold, Andreas Dahl, Michael Brand
Publicado en: nature communications, Edición 12(1), 2021, Página(s) 1125, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-21427-6

A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord.

Autores: Tsata V, Möllmert S, Schweitzer C, Kolb J, Möckel C, Böhm B, Rosso G, Lange C, Lesche M, Hammer J, Kesavan G, Beis D, Guck J, Brand M, Wehner D
Publicado en: Developmental Cell, Edición 56(4), 2021, Página(s) 509-524.e9, ISSN 1534-5807
Editor: Cell Press
DOI: 10.1016/j.devcel.2020.12.009

In Vivo Chemical Screen in Zebrafish Embryos Identifies Regulators of Hematopoiesis Using a Semiautomated Imaging Assay

Autores: Guruchandar Arulmozhivarman, Martin Stöter, Marc Bickle, Martin Kräter, Manja Wobus, Gerhard Ehninger, Friedrich Stölzel, Michael Brand, Martin Bornhäuser, Nona Shayegi
Publicado en: Journal of Biomolecular Screening, Edición 21/9, 2016, Página(s) 956-964, ISSN 1087-0571
Editor: Sage Science Press
DOI: 10.1177/1087057116644163

Role of the immune response in initiating central nervous system regeneration in vertebrates: learning from the fish

Autores: Viktoria Bosak, Kei Murata, Oliver Bludau, Michael Brand
Publicado en: The International Journal of Developmental Biology, Edición 62/6-7-8, 2018, Página(s) 403-417, ISSN 0214-6282
Editor: University of the Basque Country Press
DOI: 10.1387/IJDB.180033VB

Cre-inducible site-specific recombination in zebrafish oligodendrocytes

Autores: Alejandro Pinzon-Olejua, Cornelia Welte, Avinash Chekuru, Viktoria Bosak, Michael Brand, Stefan Hans, Claudia A.O. Stuermer
Publicado en: Developmental Dynamics, Edición 246/1, 2017, Página(s) 41-49, ISSN 1058-8388
Editor: John Wiley & Sons Inc.
DOI: 10.1002/dvdy.24458

Targeted knock-in of CreERT2 in zebrafish using CRISPR/Cas9

Autores: Gokul Kesavan, Juliane Hammer, Stefan Hans, Michael Brand
Publicado en: Cell and Tissue Research, Edición 372/1, 2018, Página(s) 41-50, ISSN 0302-766X
Editor: Springer Verlag
DOI: 10.1007/s00441-018-2798-x

Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development

Autores: Jonathan Henninger, Buyung Santoso, Stefan Hans, Ellen Durand, Jessica Moore, Christian Mosimann, Michael Brand, David Traver, Leonard Zon
Publicado en: Nature Cell Biology, Edición 19/1, 2017, Página(s) 17-27, ISSN 1465-7392
Editor: Nature Publishing Group
DOI: 10.1038/ncb3444

Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: - Preclinical Validation in Human CD34+ Stem and Progenitor Cells

Autores: Guruchandar Arulmozhivarman, Martin Kräter, Manja Wobus, Jens Friedrichs, Elham Pishali Bejestani, Katrin Müller, Katrin Lambert, Dimitra Alexopoulou, Andreas Dahl, Martin Stöter, Marc Bickle, Nona Shayegi, Jochen Hampe, Friedrich Stölzel, Michael Brand, Malte von Bonin, Martin Bornhäuser
Publicado en: Scientific Reports, Edición 7/1, 2017, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-017-12360-0

Radiobiological effects and proton RBE determined by wildtype zebrafish embryos

Autores: Emília Rita Szabó, Michael Brand, Stefan Hans, Katalin Hideghéty, Leonhard Karsch, Elisabeth Lessmann, Jörg Pawelke, Michael Schürer, Elke Beyreuther
Publicado en: PLOS ONE, Edición 13/11, 2018, Página(s) e0206879, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0206879

CRISPR/Cas9-Mediated Zebrafish Knock-in as a Novel Strategy to Study Midbrain-Hindbrain Boundary Development

Autores: Gokul Kesavan, Avinash Chekuru, Anja Machate, Michael Brand
Publicado en: Frontiers in Neuroanatomy, Edición 11, 2017, ISSN 1662-5129
Editor: Frontiers Research Foundation
DOI: 10.3389/fnana.2017.00052

Immune Suppressive and Bone Inhibitory Effects of Prednisolone in Growing and Regenerating Zebrafish Tissues

Autores: Karina Geurtzen, Aude Vernet, Andrew Freidin, Martina Rauner, Lorenz C Hofbauer, Jürgen E Schneider, Michael Brand, Franziska Knopf
Publicado en: Journal of Bone and Mineral Research, 2017, ISSN 0884-0431
Editor: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3231

Distinct roles of neuroepithelial-like and radial glia-like progenitor cells in cerebellar regeneration

Autores: Jan Kaslin, Volker Kroehne, Julia Ganz, Stefan Hans, Michael Brand
Publicado en: Development, Edición 144/8, 2017, Página(s) 1462-1471, ISSN 0950-1991
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dev.144907

Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth

Autores: Sumeet Pal Singh, Sharan Janjuha, Theresa Hartmann, Özge Kayisoglu, Judith Konantz, Sarah Birke, Priyanka Murawala, Ezzaldin Ahmed Alfar, Kei Murata, Anne Eugster, Naoki Tsuji, Edward R. Morrissey, Michael Brand, Nikolay Ninov
Publicado en: Nature Communications, Edición 8/1, 2017, Página(s)  664, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-017-00461-3

Cell-fate plasticity, adhesion and cell sorting complementarily establish a sharp midbrain-hindbrain boundary

Autores: Gokul Kesavan, Anja Machate, Stefan Hans, Michael Brand
Publicado en: Development, Edición 147/11, 2020, Página(s) dev186882, ISSN 0950-1991
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dev.186882

Zebrafish Spinal Cord Repair Is Accompanied by Transient Tissue Stiffening

Autores: Stephanie Möllmert, Maria A. Kharlamova, Tobias Hoche, Anna V. Taubenberger, Shada Abuhattum, Veronika Kuscha, Thomas Kurth, Michael Brand, Jochen Guck
Publicado en: Biophysical Journal, Edición 118/2, 2020, Página(s) 448-463, ISSN 0006-3495
Editor: Biophysical Society
DOI: 10.1016/j.bpj.2019.10.044

Book chapters (1)

The Zebrafish Cerebellum

Autores: Jan Kaslin, Michael Brand
Publicado en: Essentials of Cerebellum and Cerebellar Disorders, 2016, Página(s) 411-421
Editor: Springer International Publishing
DOI: 10.1007/978-3-319-24551-5_56

Other (1)

Loss of lrrk2 impairs dopamine catabolism, cell proliferation, and neuronal regeneration in the zebrafish brain

Autores: Stefano Suzzi, Reiner Ahrendt, Stefan Hans, Svetlana A. Semenova, Saygin Bilican, Shady Sayed, Sylke Winkler, Sandra Spiess, Jan Kaslin, Pertti Panula, Michael Brand
Publicado en: bioRxiv, Edición 140608, 2017
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/140608