Regeneration of the adult zebrafish brain

Informazioni relative al progetto

ZF-BrainReg

ID dell’accordo di sovvenzione: 669811

DOI

10.3030/669811

Progetto chiuso

Data della firma CE 19 Ottobre 2015

Data di avvio 1 Gennaio 2016

Data di completamento 31 Dicembre 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 2 500 000,00

Contributo UE

€ 2 500 000,00

Coordinato da

TECHNISCHE UNIVERSITAET DRESDEN
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (21)

Single cell sequencing of radial glia progeny reveals the diversity of newborn neurons in the adult zebrafish brain

Autori: Christian Lange, Fabian Rost, Anja Machate, Susanne Reinhardt, Matthias Lesche, Anke Weber, Veronika Kuscha, Andreas Dahl, Steffen Rulands, Michael Brand
Pubblicato in: Development, Numero 147/1, 2020, Pagina/e dev185595, ISSN 0950-1991
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dev.185595

Isthmin1, a secreted signaling protein, acts downstream of diverse embryonic patterning centers in development

Autori: Kesavan G, Raible F, Gupta M, Machate A, Yilmaz D, Brand M
Pubblicato in: Cell Tissue Research, Numero 383(3), 2020, Pagina/e 987-1002, ISSN 0302-766X
Editore: Springer Verlag
DOI: 10.1007/s00441-020-03318-2

Electrophysiological Properties of Adult Zebrafish Oligodendrocyte Progenitor Cells

Autori: Vasiliki Tsata, Volker Kroehne, Susanne Reinhardt, Ali El-Armouche, Michael Brand, Michael Wagner, Michell M. Reimer
Pubblicato in: Frontiers in Cellular Neuroscience, Numero 13, 2019, ISSN 1662-5102
Editore: Frontiers Research Foundation
DOI: 10.3389/fncel.2019.00102

Heparan sulfate proteoglycan expression in the regenerating zebrafish fin.

Autori: Keil S, Gupta M, Brand M, Knopf F.
Pubblicato in: Developmental Dynamics, Numero 250(9), 2021, Pagina/e 1368-1380, ISSN 1058-8388
Editore: John Wiley & Sons Inc.
DOI: 10.1002/dvdy.321

Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain.

Autori: Suzzi S, Ahrendt R, Hans S, Semenova SA, Chekuru A, Wirsching P, Kroehne V, Bilican S, Sayed S, Winkler S, Spieß S, Machate A, Kaslin J, Panula P, Brand M
Pubblicato in: PLoS Genetics, Numero 7(9), 2021, Pagina/e e1009794, ISSN 1553-7390
Editore: Public Library of Science
DOI: 10.1371/journal.pgen.1009794

Polyacrylamide Bead Sensors for in vivo Quantification of Cell-Scale Stress in Zebrafish Development

Autori: N. Träber, K. Uhlmann, S. Girardo, G. Kesavan, K. Wagner, J. Friedrichs, R. Goswami, K. Bai, M. Brand, C. Werner, D. Balzani, J. Guck
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-53425-6

Cre-Controlled CRISPR mutagenesis provides fast and easy conditional gene inactivation in zebrafish.

Autori: Stefan Hans, Daniela Zöller, Juliane Hammer, Johanna Stucke, Sandra Spieß, Gokul Kesavan, Volker Kroehne, Juan Sebastian Eguiguren, Diana Ezhkova, Andreas Petzold, Andreas Dahl, Michael Brand
Pubblicato in: nature communications, Numero 12(1), 2021, Pagina/e 1125, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-21427-6

A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord.

Autori: Tsata V, Möllmert S, Schweitzer C, Kolb J, Möckel C, Böhm B, Rosso G, Lange C, Lesche M, Hammer J, Kesavan G, Beis D, Guck J, Brand M, Wehner D
Pubblicato in: Developmental Cell, Numero 56(4), 2021, Pagina/e 509-524.e9, ISSN 1534-5807
Editore: Cell Press
DOI: 10.1016/j.devcel.2020.12.009

In Vivo Chemical Screen in Zebrafish Embryos Identifies Regulators of Hematopoiesis Using a Semiautomated Imaging Assay

Autori: Guruchandar Arulmozhivarman, Martin Stöter, Marc Bickle, Martin Kräter, Manja Wobus, Gerhard Ehninger, Friedrich Stölzel, Michael Brand, Martin Bornhäuser, Nona Shayegi
Pubblicato in: Journal of Biomolecular Screening, Numero 21/9, 2016, Pagina/e 956-964, ISSN 1087-0571
Editore: Sage Science Press
DOI: 10.1177/1087057116644163

Role of the immune response in initiating central nervous system regeneration in vertebrates: learning from the fish

Autori: Viktoria Bosak, Kei Murata, Oliver Bludau, Michael Brand
Pubblicato in: The International Journal of Developmental Biology, Numero 62/6-7-8, 2018, Pagina/e 403-417, ISSN 0214-6282
Editore: University of the Basque Country Press
DOI: 10.1387/IJDB.180033VB

Cre-inducible site-specific recombination in zebrafish oligodendrocytes

Autori: Alejandro Pinzon-Olejua, Cornelia Welte, Avinash Chekuru, Viktoria Bosak, Michael Brand, Stefan Hans, Claudia A.O. Stuermer
Pubblicato in: Developmental Dynamics, Numero 246/1, 2017, Pagina/e 41-49, ISSN 1058-8388
Editore: John Wiley & Sons Inc.
DOI: 10.1002/dvdy.24458

Targeted knock-in of CreERT2 in zebrafish using CRISPR/Cas9

Autori: Gokul Kesavan, Juliane Hammer, Stefan Hans, Michael Brand
Pubblicato in: Cell and Tissue Research, Numero 372/1, 2018, Pagina/e 41-50, ISSN 0302-766X
Editore: Springer Verlag
DOI: 10.1007/s00441-018-2798-x

Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development

Autori: Jonathan Henninger, Buyung Santoso, Stefan Hans, Ellen Durand, Jessica Moore, Christian Mosimann, Michael Brand, David Traver, Leonard Zon
Pubblicato in: Nature Cell Biology, Numero 19/1, 2017, Pagina/e 17-27, ISSN 1465-7392
Editore: Nature Publishing Group
DOI: 10.1038/ncb3444

Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: - Preclinical Validation in Human CD34+ Stem and Progenitor Cells

Autori: Guruchandar Arulmozhivarman, Martin Kräter, Manja Wobus, Jens Friedrichs, Elham Pishali Bejestani, Katrin Müller, Katrin Lambert, Dimitra Alexopoulou, Andreas Dahl, Martin Stöter, Marc Bickle, Nona Shayegi, Jochen Hampe, Friedrich Stölzel, Michael Brand, Malte von Bonin, Martin Bornhäuser
Pubblicato in: Scientific Reports, Numero 7/1, 2017, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-017-12360-0

Radiobiological effects and proton RBE determined by wildtype zebrafish embryos

Autori: Emília Rita Szabó, Michael Brand, Stefan Hans, Katalin Hideghéty, Leonhard Karsch, Elisabeth Lessmann, Jörg Pawelke, Michael Schürer, Elke Beyreuther
Pubblicato in: PLOS ONE, Numero 13/11, 2018, Pagina/e e0206879, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0206879

CRISPR/Cas9-Mediated Zebrafish Knock-in as a Novel Strategy to Study Midbrain-Hindbrain Boundary Development

Autori: Gokul Kesavan, Avinash Chekuru, Anja Machate, Michael Brand
Pubblicato in: Frontiers in Neuroanatomy, Numero 11, 2017, ISSN 1662-5129
Editore: Frontiers Research Foundation
DOI: 10.3389/fnana.2017.00052

Immune Suppressive and Bone Inhibitory Effects of Prednisolone in Growing and Regenerating Zebrafish Tissues

Autori: Karina Geurtzen, Aude Vernet, Andrew Freidin, Martina Rauner, Lorenz C Hofbauer, Jürgen E Schneider, Michael Brand, Franziska Knopf
Pubblicato in: Journal of Bone and Mineral Research, 2017, ISSN 0884-0431
Editore: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.3231

Distinct roles of neuroepithelial-like and radial glia-like progenitor cells in cerebellar regeneration

Autori: Jan Kaslin, Volker Kroehne, Julia Ganz, Stefan Hans, Michael Brand
Pubblicato in: Development, Numero 144/8, 2017, Pagina/e 1462-1471, ISSN 0950-1991
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dev.144907

Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth

Autori: Sumeet Pal Singh, Sharan Janjuha, Theresa Hartmann, Özge Kayisoglu, Judith Konantz, Sarah Birke, Priyanka Murawala, Ezzaldin Ahmed Alfar, Kei Murata, Anne Eugster, Naoki Tsuji, Edward R. Morrissey, Michael Brand, Nikolay Ninov
Pubblicato in: Nature Communications, Numero 8/1, 2017, Pagina/e  664, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-017-00461-3

Cell-fate plasticity, adhesion and cell sorting complementarily establish a sharp midbrain-hindbrain boundary

Autori: Gokul Kesavan, Anja Machate, Stefan Hans, Michael Brand
Pubblicato in: Development, Numero 147/11, 2020, Pagina/e dev186882, ISSN 0950-1991
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dev.186882

Zebrafish Spinal Cord Repair Is Accompanied by Transient Tissue Stiffening

Autori: Stephanie Möllmert, Maria A. Kharlamova, Tobias Hoche, Anna V. Taubenberger, Shada Abuhattum, Veronika Kuscha, Thomas Kurth, Michael Brand, Jochen Guck
Pubblicato in: Biophysical Journal, Numero 118/2, 2020, Pagina/e 448-463, ISSN 0006-3495
Editore: Biophysical Society
DOI: 10.1016/j.bpj.2019.10.044

Book chapters (1)

The Zebrafish Cerebellum

Autori: Jan Kaslin, Michael Brand
Pubblicato in: Essentials of Cerebellum and Cerebellar Disorders, 2016, Pagina/e 411-421
Editore: Springer International Publishing
DOI: 10.1007/978-3-319-24551-5_56

Other (1)

Loss of lrrk2 impairs dopamine catabolism, cell proliferation, and neuronal regeneration in the zebrafish brain

Autori: Stefano Suzzi, Reiner Ahrendt, Stefan Hans, Svetlana A. Semenova, Saygin Bilican, Shady Sayed, Sylke Winkler, Sandra Spiess, Jan Kaslin, Pertti Panula, Michael Brand
Pubblicato in: bioRxiv, Numero 140608, 2017
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/140608