Cochlear Optogenetics for Auditory Research and Prosthetics

Publicaciones

Understanding and treating paediatric hearing impairment.

Autores: Christian Wrobel; Maria-Patapia Zafeiriou; Tobias Moser
Publicado en: EBioMedicine, Edición 63, 2021, Página(s) 103171-, ISSN 2352-3964
Editor: Elsevier BV
DOI: 10.1016/j.ebiom.2020.103171

En route to sound coding strategies for optical cochlear implants

Autores: Lakshay Khurana; Tamas Harczos; Tobias Moser; Lukasz Jablonski
Publicado en: iScience, Edición 26(10), 2023, ISSN 2589-0042
Editor: Cell Press
DOI: 10.1016/j.isci.2023.107725

Utility of red‐light ultrafast optogenetic stimulation of the auditory pathway

Autores: Burak Bali, David Lopez de la Morena, Artur Mittring, Thomas Mager, Vladan Rankovic, Antoine Tarquin Huet, Tobias Moser
Publicado en: EMBO Molecular Medicine, Edición 13/6, 2021, ISSN 1757-4676
Editor: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202013391

Towards optogenetic approaches for hearing restoration

Autores: Tobias Moser, Alexander Dieter
Publicado en: Biochemical and Biophysical Research Communications, Edición 527/2, 2020, Página(s) 337-342, ISSN 0006-291X
Editor: Academic Press
DOI: 10.1016/j.bbrc.2019.12.126

Restoring Hearing with Light

Autores: Moser, T
Publicado en: GMS Zeitschrift für Audiologie - Audiological Acoustics; VOL: 5; DOC01 /20230120/, Edición 5, 2023, ISSN 2628-9083
Editor: Deutsche Gesellschaft für Audiologie

Multiscale photonic imaging of the native and implanted cochlea

Autores: Daniel Keppeler, Christoph A. Kampshoff, Anupriya Thirumalai, Carlos J. Duque-Afonso, Jannis J. Schaeper, Tabea Quilitz, Mareike Töpperwien, Christian Vogl, Roland Hessler, Alexander Meyer, Tim Salditt, Tobias Moser
Publicado en: Proceedings of the National Academy of Sciences of the USA, Edición 118(18), 2021, Página(s) e2014472118, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2014472118

Towards the optical cochlear implant: optogenetic approaches for hearing restoration

Autores: Alexander Dieter, Daniel Keppeler, Tobias Moser
Publicado en: EMBO Molecular Medicine, Edición 12/4, 2020, ISSN 1757-4676
Editor: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201911618

Fast photoswitchable molecular prosthetics control neuronal activity in the cochlea

Autores: G. Aida; H. Antoine; C. Matera; T. Anupriya; T. Anupriya; L. Amadeu; M. Tobias; M. Tobias; G. Pau
Publicado en: ournal of the American Chemical Society, Edición 144, 21, 2022, Página(s) 9229-9239, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1101/2021.05.25.445123

Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice

Autores: Burak Bali; Eva Gruber-Dujardin; Kathrin Kusch; Vladan Rankovic; Tobias Moser
Publicado en: Life Science Alliance, Edición 5(8), 2022, ISSN 2575-1077
Editor: Life Science Alliance, LLC
DOI: 10.26508/lsa.202101338

Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users

Autores: Hunniford, Victoria; Kühler, Robert; Wolf, Bettina; Keppeler, Daniel; Strenzke, Nicola; Moser, Tobias; Hunniford, Victoria; 1Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany; Kühler, Robert; 3Department of Otolaryngology, University Medical Center Göttingen, Göttingen, Germany; Wolf, Bettina; 1Institute for Auditory Neuroscience and
Publicado en: Frontiers in Neuroscience, Edición 17, 2023, ISSN 1662-4548
Editor: Frontiers Research Foundation
DOI: 10.3389/fnins.2023.1105562

Propagation-based phase-contrast x-ray tomography of cochlea using a compact synchrotron source

Autores: Mareike Töpperwien, Regine Gradl, Daniel Keppeler, Malte Vassholz, Alexander Meyer, Roland Hessler, Klaus Achterhold, Bernhard Gleich, Martin Dierolf, Franz Pfeiffer, Tobias Moser, Tim Salditt
Publicado en: Scientific Reports, Edición 8/1, 2018, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-018-23144-5

High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics

Autores: Thomas Mager, David Lopez de la Morena, Verena Senn, Johannes Schlotte, Anna D´Errico, Katrin Feldbauer, Christian Wrobel, Sangyong Jung, Kai Bodensiek, Vladan Rankovic, Lorcan Browne, Antoine Huet, Josephine Jüttner, Phillip G. Wood, Johannes J. Letzkus, Tobias Moser, Ernst Bamberg
Publicado en: Nature Communications, Edición 9/1, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-018-04146-3

Optogenetic stimulation of cochlear neurons activates the auditory pathway and restores auditory-driven behavior in deaf adult gerbils

Autores: Christian Wrobel, Alexander Dieter, Antoine Huet, Daniel Keppeler, Carlos J. Duque-Afonso, Christian Vogl, Gerhard Hoch, Marcus Jeschke, Tobias Moser
Publicado en: Science Translational Medicine, Edición 10/449, 2018, Página(s) eaao0540, ISSN 1946-6234
Editor: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aao0540

Near physiological spectral selectivity of cochlear optogenetics

Autores: Alexander Dieter, Carlos J. Duque-Afonso, Vladan Rankovic, Marcus Jeschke, Tobias Moser
Publicado en: Nature Communications, Edición 10/1, 2019, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-09980-7

Ultrafast optogenetic stimulation of the auditory pathway by targeting‐optimized Chronos

Autores: Daniel Keppeler, Ricardo Martins Merino, David Lopez de la Morena, Burak Bali, Antoine Tarquin Huet, Anna Gehrt, Christian Wrobel, Swati Subramanian, Tobias Dombrowski, Fred Wolf, Vladan Rankovic, Andreas Neef, Tobias Moser
Publicado en: The EMBO Journal, Edición 37/24, 2018, Página(s) e99649, ISSN 0261-4189
Editor: Nature Publishing Group
DOI: 10.15252/embj.201899649

μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve

Autores: Alexander Dieter, Eric Klein, Daniel Keppeler, Lukasz Jablonski, Tamas Harczos, Gerhard Hoch, Vladan Rankovic, Oliver Paul, Marcus Jeschke, Patrick Ruther, Tobias Moser
Publicado en: EMBO Molecular Medicine, Edición e12387, 2020, ISSN 1757-4676
Editor: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202012387

Viral rhodopsins 1 are an unique family of light-gated cation channels

Autores: Dmitrii Zabelskii, Alexey Alekseev, Kirill Kovalev, Vladan Rankovic, Taras Balandin, Dmytro Soloviov, Dmitry Bratanov, Ekaterina Savelyeva, Elizaveta Podolyak, Dmytro Volkov, Svetlana Vaganova, Roman Astashkin, Igor Chizhov, Natalia Yutin, Maksim Rulev, Alexander Popov, Ana-Sofia Eria-Oliveira, Tatiana Rokitskaya, Thomas Mager, Yuri Antonenko, Riccardo Rosselli, Grigoriy Armeev, Konstantin Shaitan
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-19457-7

Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants

Autores: Antoine Tarquin Huet, Tobias Dombrowski, Vladan Rankovic, Anupriya Thirumalai, Tobias Moser
Publicado en: Frontiers in Molecular Neuroscience, Edición 14, 2021, ISSN 1662-5099
Editor: Frontiers Research Foundation
DOI: 10.3389/fnmol.2021.635897

Devising a framework of optogenetic coding in the auditory pathway: Insights from auditory midbrain recordings

Autores: Maria Michael; Bettina Julia Wolf; Astrid Klinge-Strahl; Marcus Jeschke; Tobias Moser; Alexander Dieter
Publicado en: Brain Stimulation, Edición 16, 2023, Página(s) 1486-1500, ISSN 1935-861X
Editor: Elsevier BV
DOI: 10.1016/j.brs.2023.09.018

Graded optogenetic activation of the auditory pathway for hearing restoration

Autores: Artur Mittring; Tobias Moser; Antoine Huet
Publicado en: Brain Stimulation, Edición 16(2), 2024, Página(s) 466-483, ISSN 1935-861X
Editor: Elsevier BV
DOI: 10.1101/2022.09.05.506618

Is there an unmet medical need for improved hearing restoration?

Autores: Bettina Julia Wolf; Kathrin Kusch; Victoria Hunniford; Barbara Vona; Robert Kühler; Daniel Keppeler; Nicola Strenzke; Tobias Moser
Publicado en: Embo Molecular Medicine, Edición 14:e15798, 2022, ISSN 1757-4676
Editor: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202215798

Derechos de propiedad intelectual

MUTANT LIGHT-INDUCIBLE ION CHANNEL OF CHRIMSON

Número de solicitud/publicación: 20 17063458
Fecha: 2017-06-02
Solicitante(s): UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS

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