Deliverables Documents, reports (5) Researcher Declaration Declaration of ESRs Recruitment Recruitment of ESRs for TASPPI finalized Career Development Plan Career Plan for all ESRs finalized Businessplan Startup Businessplan for the spin-off of TASPPI Open Access Publication(s) Publications in peer-reviewed journals Publications Peer reviewed articles (15) Biophysical and structural insight into the USP8/14-3-3 interaction Author(s): Federica Centorrino, Alice Ballone, Madita Wolter, Christian Ottmann Published in: FEBS Letters, Issue 592, 2018, Page(s) 1211-1220, ISSN 0014-5793 Publisher: Elsevier BV DOI: 10.1002/1873-3468.13017 14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2) Author(s): Katarina Psenakova, Olivia Petrvalska, Salome Kylarova, Domenico Lentini Santo, Dana Kalabova, Petr Herman, Veronika Obsilova, Tomas Obsil Published in: Biochimica et Biophysica Acta (BBA) - General Subjects, Issue 1862, 2018, Page(s) 1612-1625, ISSN 0304-4165 Publisher: Elsevier BV DOI: 10.1016/j.bbagen.2018.04.006 Structural characterization of 14-3-3ζ in complex with the human Son of sevenless homolog 1 (SOS1) Author(s): Alice Ballone, Federica Centorrino, Madita Wolter, Christian Ottmann Published in: Journal of Structural Biology, Issue 202, 2018, Page(s) 210-215, ISSN 1047-8477 Publisher: Academic Press DOI: 10.1016/j.jsb.2018.01.011 Backbone chemical shift assignments of human 14-3-3σ Author(s): João Filipe Neves, Isabelle Landrieu, Hamida Merzougui, Emmanuelle Boll, Xavier Hanoulle, François-Xavier Cantrelle Published in: Biomolecular NMR Assignments, Issue 13/1, 2019, Page(s) 103-107, ISSN 1874-2718 Publisher: Springer Verlag DOI: 10.1007/s12104-018-9860-1 Protein X-ray crystallography of the 14-3-3ζ/SOS1 complex Author(s): Alice Ballone, Federica Centorrino, Madita Wolter, Christian Ottmann Published in: Data in Brief, Issue 19, 2018, Page(s) 1683-1687, ISSN 2352-3409 Publisher: Elsevier BV DOI: 10.1016/j.dib.2018.06.060 14-3-3: A Case Study in PPI Modulation Author(s): Alice Ballone, Federica Centorrino, Christian Ottmann Published in: Molecules, Issue 23/6, 2018, Page(s) 1386, ISSN 1420-3049 Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/molecules23061386 Interaction of an IκBα Peptide with 14-3-3 Author(s): Madita Wolter, Domenico Lentini Santo, Petr Herman, Alice Ballone, Federica Centorrino, Tomas Obsil, Christian Ottmann Published in: ACS Omega, Issue 5/10, 2020, Page(s) 5380-5388, ISSN 2470-1343 Publisher: ACS Publications DOI: 10.1021/acsomega.9b04413 Allosteric activation of yeast enzyme neutral trehalase by calcium and 14-3-3 protein Author(s): M. Alblova, A. Smidova, D. Kalabova, D. Lentini Santo, T. Obsil, V Obsilova. Obsilova Published in: Physiological Research, Issue 68, 2019, Page(s) 147-160, ISSN 0862-8408 Publisher: Akademie Ved Ceske Republiky DOI: 10.33549/physiolres.933950 Set-up and screening of a fragment library targeting the 14-3-3 protein interface Author(s): Dario Valenti, João Filipe Neves, François-Xavier Cantrelle, Stanimira Hristeva, Domenico Lentini Santo, Tomáš Obšil, Xavier Hanoulle, Laura M. Levy, Dimitrios Tzalis, Isabelle Landrieu, Christian Ottmann Published in: MedChemComm, Issue 10/10, 2019, Page(s) 1796-1802, ISSN 2040-2503 Publisher: Royal Society of Chemistry DOI: 10.1039/c9md00215d Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3σ Author(s): Ave Kuusk, João Filipe Neves, Kenny Bravo-Rodriguez, Anders Gunnarsson, Yasser B. Ruiz-Blanco, Michael Ehrmann, Hongming Chen, Isabelle Landrieu, Elsa Sanchez-Garcia, Helen Boyd, Christian Ottmann, Richard G. Doveston Published in: ACS Chemical Biology, Issue 15/1, 2019, Page(s) 262-271, ISSN 1554-8929 Publisher: American Chemical Society DOI: 10.1021/acschembio.9b00893 Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes Author(s): Sebastian A. Andrei, Femke A. Meijer, João Filipe Neves, Luc Brunsveld, Isabelle Landrieu, Christian Ottmann, Lech-Gustav Milroy Published in: ACS Chemical Neuroscience, Issue 9/11, 2018, Page(s) 2639-2654, ISSN 1948-7193 Publisher: American Chemical Society DOI: 10.1021/acschemneuro.8b00118 Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein–Protein Interaction Author(s): Leire Iralde-Lorente, Giusy Tassone, Letizia Clementi, Lorenzo Franci, Claire C Munier, Ylenia Cau, Mattia Mori, Mario Chiariello, Adriano Angelucci, Matthew W. D. Perry, Cecilia Pozzi, Stefano Mangani, Maurizio Botta Published in: ACS Chemical Biology, 2020, ISSN 1554-8929 Publisher: American Chemical Society DOI: 10.1021/acschembio.0c00039 Clinical candidates modulating protein-protein interactions: The fragment-based experience Author(s): Dario Valenti, Stanimira Hristeva, Dimitrios Tzalis, Christian Ottmann Published in: European Journal of Medicinal Chemistry, Issue 167, 2019, Page(s) 76-95, ISSN 0223-5234 Publisher: Elsevier BV DOI: 10.1016/j.ejmech.2019.01.084 AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins Author(s): Maria Saline, Lukas Badertscher, Madita Wolter, Roxanne Lau, Anders Gunnarsson, Tomas Jacso, Tyrrell Norris, Christian Ottmann, Arjan Snijder Published in: Journal of Biological Chemistry, Issue 294/35, 2019, Page(s) 13106-13116, ISSN 0021-9258 Publisher: American Society for Biochemistry and Molecular Biology Inc. DOI: 10.1074/jbc.ra119.008649 Design Of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization Author(s): Francesco Bosica, Sebastian Andrei, João Filipe Neves, Peter Brandt, Anders Gunnarsson, Isabelle Landrieu, Christian Ottmann, Gavin O'Mahony Published in: Chemistry - A European Journal, 2020, ISSN 0947-6539 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/chem.202001608 Book chapters (1) Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications Author(s): Clément Danis, Elian Dupré, Xavier Hanoulle, Isabelle Landrieu, Alessia Lasorsa, João Filipe Neves, Robert Schneider, Caroline Smet-Nocca Published in: Tau Biology, Issue 1184, 2019, Page(s) 35-45, ISBN 978-981-32-9357-1 Publisher: Springer Singapore DOI: 10.1007/978-981-32-9358-8_3 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available