Objective
Tendon Therapy Train is a research, training and innovation programme for human and equine tendon repair and regeneration that will exploit recent advancements in tissue engineering by self-assembly (TESA) technologies which have led to the clinical translation and commercialisation of advanced therapy medicinal products (ATMPs). Although TESA therapies have the potential to revolutionise healthcare for numerous clinical targets, a lack of researchers with the necessary interdisciplinary skillset to advance the field is limiting clinical translation. Tendon therapy train, a network of 8 beneficiaries and 8 partners (7 universities, 7 companies and 2 hospitals) from six countries across Europe, will train a cohort of 15 researchers to doctoral level in the interdisciplinary area of ATMPs. The innovative credentials of the research and training programme involve engineering suitable ex vivo culture environments that, by mimicking the native tendon tissue milieu (human and equine), will maintain the tenogenic phenotype of tendon derived cells and differentiate non-tendon derived cells (stem cells and dermal fibroblasts) towards the tenogenic lineage, subsequently enabling development of three-dimensional cell-assembled tissue equivalents, the clinical potential of which will be assessed in suitable preclinical models. The comprehensive Tendon Therapy Train programme will equip researchers with transferable inter- and multidisciplinary skills that will further European-based knowledge, innovation, competitiveness and leadership in the field of TESA / ATMP and ultimately enable clinical translation and commercialisation of the developed technologies.
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugs
- medical and health sciencesbasic medicinephysiologypathophysiology
- medical and health sciencesmedical biotechnologytissue engineering
- medical and health sciencesmedical biotechnologycells technologiesstem cells
- medical and health sciencesclinical medicinesurgerysurgical procedures
Programme(s)
Funding Scheme
MSCA-ITN-ETN - European Training NetworksCoordinator
H91 Galway
Ireland
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Participants (8)
4704 553 Braga
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NW1 OTU London
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6200 MD Maastricht
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01600 Trevoux
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45110 Ioannina
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Participation ended
38000 Grenoble
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
H91 Galway
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
CB25 9TL Cambridge
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partners (7)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
Galway
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
Thessaloniki
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
38221 Volos
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
ME4 4QZ Chatham
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
38670 Chasse Sur Rhone
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
80686 Munchen
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
Waterloo
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