Objective
Tendon Therapy Train is a research, training and innovation programme for human and equine tendon repair and regeneration that will exploit recent advancements in tissue engineering by self-assembly (TESA) technologies which have led to the clinical translation and commercialisation of advanced therapy medicinal products (ATMPs). Although TESA therapies have the potential to revolutionise healthcare for numerous clinical targets, a lack of researchers with the necessary interdisciplinary skillset to advance the field is limiting clinical translation. Tendon therapy train, a network of 8 beneficiaries and 8 partners (7 universities, 7 companies and 2 hospitals) from six countries across Europe, will train a cohort of 15 researchers to doctoral level in the interdisciplinary area of ATMPs. The innovative credentials of the research and training programme involve engineering suitable ex vivo culture environments that, by mimicking the native tendon tissue milieu (human and equine), will maintain the tenogenic phenotype of tendon derived cells and differentiate non-tendon derived cells (stem cells and dermal fibroblasts) towards the tenogenic lineage, subsequently enabling development of three-dimensional cell-assembled tissue equivalents, the clinical potential of which will be assessed in suitable preclinical models. The comprehensive Tendon Therapy Train programme will equip researchers with transferable inter- and multidisciplinary skills that will further European-based knowledge, innovation, competitiveness and leadership in the field of TESA / ATMP and ultimately enable clinical translation and commercialisation of the developed technologies.
Fields of science
- natural sciencesphysical sciencesastronomyplanetary scienceplanetary geology
- medical and health sciencesmedical biotechnologycells technologiesstem cells
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drug
- natural sciencesbiological sciencescell biology
- medical and health sciencesmedical biotechnologytissue engineering
Programme(s)
Call for proposal
H2020-MSCA-ITN-2015
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Funding Scheme
MSCA-ITN-ETN - European Training NetworksCoordinator
H91 Galway
Ireland
Participants (8)
4704 553 Braga
NW1 OTU London
6200 MD Maastricht
01600 Trevoux
45110 Ioannina
Participation ended
38000 Grenoble
H91 Galway
CB25 9TL Cambridge
Partners (7)
Galway
Thessaloniki
38221 Volos
ME4 4QZ Chatham
38670 Chasse Sur Rhone
80686 Munchen
Waterloo