Deliverables Websites, patent fillings, videos etc. (2) IDF and patent filings To protect intellectual property, three patents strengthening European innovation in cell-based therapy development will be filed: i) methods to differentiate dermal fibroblasts (DFs) and stem cells (BMSCs) towards tenogenic lineage; ii) methods to maintain tendon-specific function in vitro; and iii) the final tendon substitute products. Digital media dissemination Led by NUI Galway, digital media dissemination will include the Tendon Therapy website and dedicated project accounts on social media including twitter and linked-in. All press releases will also be issued electronically. Documents, reports (5) Supervisory Board of the Network supervisory agreement Ethics provide documents linked to the ethics issues Progress report progress report Draft Periodic Report periodic report Mid Term review meeting mid term review meeting Publications Peer reviewed articles (23) Natural Architectures for Tissue Engineering and Regenerative Medicine Author(s): Floris Honig, Steven Vermeulen, Amir A. Zadpoor, Jan de Boer, Lidy E. Fratila-Apachitei Published in: Journal of Functional Biomaterials, Issue 11/3, 2020, Page(s) 47, ISSN 2079-4983 Publisher: MDPI DOI: 10.3390/jfb11030047 Screening as a strategy to drive regenerative medicine research Author(s): Steven Vermeulen, Jan de Boer Published in: Methods, 2020, ISSN 1046-2023 Publisher: Academic Press DOI: 10.1016/j.ymeth.2020.04.004 Mechanotransduction is a context-dependent activator of TGF-β signaling in mesenchymal stem cells Author(s): Steven Vermeulen, Nadia Roumans, Floris Honig, Aurélie Carlier, Dennie G.A.J. Hebels, Aysegul Dede Eren, Peter ten Dijke, Aliaksei Vasilevich, Jan de Boer Published in: Biomaterials, Issue 259, 2020, Page(s) 120331, ISSN 0142-9612 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.biomaterials.2020.120331 Advancements and Challenges in Multidomain Multicargo Delivery Vehicles Author(s): Eugenia Pugliese, João Q. Coentro, Dimitrios I. Zeugolis Published in: Advanced Materials, Issue 30/13, 2018, Page(s) 1704324, ISSN 0935-9648 Publisher: United Nations Industrial Developement Organization DOI: 10.1002/adma.201704324 Biophysics Rules the Cell Culture but Has Yet to Reach the Clinic Author(s): Salomé Guillaumin, Ignacio Sallent, Dimitrios I. Zeugolis Published in: Journal of the American Academy of Orthopaedic Surgeons, Issue 25/7, 2017, Page(s) e144-e147, ISSN 1067-151X Publisher: American Academy of Orthopaedic Surgeons DOI: 10.5435/JAAOS-D-17-00324 Micro-Topographies Promote Late Chondrogenic Differentiation Markers in the ATDC5 Cell Line Author(s): Bach Q. Le, Aliaksei Vasilevich, Steven Vermeulen, Frits Hulshof, Dimitrios F. Stamatialis, Clemens A. van Blitterswijk, Jan de Boer Published in: Tissue Engineering Part A, Issue 23/9-10, 2017, Page(s) 458-469, ISSN 1937-3341 Publisher: Mary Ann Liebert Inc. DOI: 10.1089/ten.TEA.2016.0421 Identification of topographical architectures supporting the phenotype of rat tenocytes Author(s): Steven Vermeulen, Aliaksei Vasilevich, Dimitrios Tsiapalis, Nadia Roumans, Pascal Vroemen, Nick R.M. Beijer, Aysegul Dede Eren, Dimitrios Zeugolis, Jan de Boer Published in: Acta Biomaterialia, Issue 83, 2019, Page(s) 277-290, ISSN 1742-7061 Publisher: Elsevier BV DOI: 10.1016/j.actbio.2018.10.041 Current and upcoming therapies to modulate skin scarring and fibrosis Author(s): João Q. Coentro, Eugenia Pugliese, Geoffrey Hanley, Michael Raghunath, Dimitrios I. Zeugolis Published in: Advanced Drug Delivery Reviews, Issue Theme issue format, 2018, Page(s) digital, ISSN 0169-409X Publisher: Elsevier BV DOI: 10.1016/j.addr.2018.08.009 Wound healing and scar wars Author(s): Eugenia Pugliese, João Q. Coentro, Michael Raghunath, Dimitrios I. Zeugolis Published in: Advanced Drug Delivery Reviews, Issue 129, 2018, Page(s) 1-3, ISSN 0169-409X Publisher: Elsevier BV DOI: 10.1016/j.addr.2018.05.010 Shaping Cell Fate: Influence of Topographical Substratum Properties on Embryonic Stem Cells Author(s): Sarita Kumari, Steven Vermeulen, Ben van der Veer, Aurélie Carlier, Jan de Boer, Deepa Subramanyam Published in: Tissue Engineering Part B: Reviews, Issue 24/4, 2018, Page(s) 255-266, ISSN 1937-3368 Publisher: Mary Ann Liebert Inc. DOI: 10.1089/ten.teb.2017.0468 Joint academic and industrial efforts towards innovative and efficient solutions for clinical needs Author(s): Andrea De Pieri, Sofia Ribeiro, Dimitrios Tsiapalis, David Eglin, Marc Bohner, Peter Dubruel, Philip Procter, Dimitrios I. Zeugolis, Yves Bayon Published in: Journal of Materials Science: Materials in Medicine, Issue 29/8, 2018, ISSN 0957-4530 Publisher: Kluwer Academic Publishers DOI: 10.1007/s10856-018-6136-3 The Collagen Suprafamily: From Biosynthesis to Advanced Biomaterial Development Author(s): Anna Sorushanova, Luis M. Delgado, Zhuning Wu, Naledi Shologu, Aniket Kshirsagar, Rufus Raghunath, Anne M. Mullen, Yves Bayon, Abhay Pandit, Michael Raghunath, Dimitrios I. Zeugolis Published in: Advanced Materials, Issue 31/1, 2019, Page(s) 1801651, ISSN 0935-9648 Publisher: United Nations Industrial Developement Organization DOI: 10.1002/adma.201801651 Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose‐derived stem cells Author(s): Ana I. Gonçalves, Dominika Berdecka, Márcia T. Rodrigues, Aysegul Dede Eren, Jan Boer, Rui L. Reis, Manuela E. Gomes Published in: Journal of Tissue Engineering and Regenerative Medicine, Issue 13/12, 2019, Page(s) 2204-2217, ISSN 1932-6254 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/term.2967 Decellularized Porcine Achilles tendon induces anti-inflammatory macrophage phenotype in Vitro and tendon repair in vivo Author(s): Aysegul Dede Eren, Ravi Sinha, Egemen Deniz Eren, Yuan Huipin, Sultan Gulce-Iz, Henriette Valster, Lorenzo Moroni, Jasper Foolen, Jan de Boer Published in: Journal of Immunology and Regenerative Medicine, Issue 8, 2020, Page(s) 100027, ISSN 2468-4988 Publisher: Elsevier DOI: 10.1016/j.regen.2020.100027 The synergistic effect of low oxygen tension and macromolecular crowding in the development of extracellular matrix-rich tendon equivalents Author(s): Dimitrios Tsiapalis, Andrea De Pieri, Kyriakos Spanoudes, Ignacio Sallent, Stephen Kearns, Jack L Kelly, Michael Raghunath, Dimitrios I Zeugolis Published in: Biofabrication, Issue 12/2, 2020, Page(s) 025018, ISSN 1758-5090 Publisher: IOP Publishing DOI: 10.1088/1758-5090/ab6412 Hypoxia Preconditioning of Bone Marrow Mesenchymal Stem Cells Before Implantation in Orthopaedics Author(s): Dimitrios Tsiapalis, Dimitrios I. Zeugolis Published in: Journal of the American Academy of Orthopaedic Surgeons, Issue 27/23, 2019, Page(s) e1040-e1042, ISSN 1067-151X Publisher: American Academy of Orthopaedic Surgeons DOI: 10.5435/jaaos-d-19-00044 The cytokine secretion profile of mesenchymal stromal cells is determined by surface structure of the microenvironment Author(s): Daniëlle G. Leuning, Nick R. M. Beijer, Nadia A. du Fossé, Steven Vermeulen, Ellen Lievers, Cees van Kooten, Ton J. Rabelink, Jan de Boer Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-018-25700-5 Translational Research Symposium—collaborative efforts as driving forces of healthcare innovation Author(s): João Q. Coentro, Andrea De Pieri, Diana Gaspar, Dimitrios Tsiapalis, Dimitrios I. Zeugolis, Yves Bayon Published in: Journal of Materials Science: Materials in Medicine, Issue 30/12, 2019, ISSN 0957-4530 Publisher: Kluwer Academic Publishers DOI: 10.1007/s10856-019-6339-2 ISEV2018 abstract book Author(s): Clotilde Théry, Kenneth Witwer Published in: Journal of Extracellular Vesicles, Issue 7/sup1, 2018, Page(s) 1461450, ISSN 2001-3078 Publisher: US DOI: 10.1080/20013078.2018.1461450 Local pharmacological induction of angiogenesis: Drugs for cells and cells as drugs Author(s): Diana Gaspar, Rita Peixoto, Andrea De Pieri, Britta Striegl, Dimitrios I. Zeugolis, Michael Raghunath Published in: Advanced Drug Delivery Reviews, Issue 146, 2019, Page(s) 126-154, ISSN 0169-409X Publisher: Elsevier BV DOI: 10.1016/j.addr.2019.06.002 British Society for Matrix Biology Spring 2019 Meeting: “Stroma, Niche, Repair” Author(s): Gifford. V., et. at., Published in: International Journal of Experimental Pathology, Issue 100/4, 2019, ISSN 0959-9673 Publisher: Blackwell Publishing Inc. DOI: 10.1111/iep.12332 Immune Modulation by Design: Using Topography to Control Human Monocyte Attachment and Macrophage Differentiation Author(s): Vassey, Matthew J.; Figueredo, Grazziela P.; Scurr, David; Vasilevich, Aliaksei S.; Vermeulen, Steven; Carlier, Aurélie; Luckett, Jeni; Beijer, Nick R.M.; Williams, Paul; Winkler, Dave; de Boer, Jan; Ghaemmaghami, Amir M.; Alexander, Morgan R. Published in: Advanced Science, 2020, ISSN 2198-3844 Publisher: Wiley DOI: 10.1002/advs.201903392 Seaweed polysaccharides as macromolecular crowding agents Author(s): Andrea De Pieri, Shubhasmin Rana, Stefanie Korntner, Dimitrios I. Zeugolis Published in: International Journal of Biological Macromolecules, Issue 164, 2020, Page(s) 434-446, ISSN 0141-8130 Publisher: Elsevier BV DOI: 10.1016/j.ijbiomac.2020.07.087 Book chapters (6) Bioreactors for Tendon Tissue Engineering Author(s): Ana I. Gonçalves Published in: Bioreactors for Stem Cell Expansion and Differentiation, 2018, Page(s) 269-300, ISBN 9780-429453144 Publisher: CRC Press DOI: 10.1201/9780429453144-10 Preparation and Characterization of Tissue Surrogates Rich in Extracellular Matrix Using the Principles of Macromolecular Crowding Author(s): Adrian Djalali-Cuevas, Sergio Garnica-Galvez, Andrea Rampin, Diana Gaspar, Ioannis Skoufos, Athina Tzora, Nikitas Prassinos, Nikolaos Diakakis, Dimitrios I. Zeugolis Published in: The Extracellular Matrix - Methods and Protocols, Issue 1952, 2019, Page(s) 245-259, ISBN 978-1-4939-9132-7 Publisher: Springer New York DOI: 10.1007/978-1-4939-9133-4_20 Designing Microenvironments for Optimal Outcomes in Tissue Engineering and Regenerative Medicine: From Biopolymers to Culturing Conditions Author(s): Dimitrios Tsiapalis, Sofia Ribeiro, Andrea De Pieri, Ignacio Sallent, Salomé Guillaumin, Diana Gaspar, Stefanie Korntner, Yves Bayon, Manuela E. Gomes, Rui L. Reis, Dimitrios I. Zeugolis Published in: Reference Module in Biomedical Sciences, 2019, ISBN 9780-128012383 Publisher: Elsevier DOI: 10.1016/b978-0-12-801238-3.11140-7 Scaffolds for tendon tissue engineering Author(s): Héctor Capella-Monsonís, Salomé Guillaumin, Sofia Ribeiro, Stefanie Korntner, Yves Bayon, Dimitrios I. Zeugolis Published in: Handbook of Tissue Engineering Scaffolds: Volume One, 2019, Page(s) 259-298, ISBN 9780-081025635 Publisher: Elsevier DOI: 10.1016/b978-0-08-102563-5.00013-7 The effect of aligned electrospun fibers and macromolecular crowding in tenocyte culture Author(s): Dimitrios Tsiapalis, Shubhasmin Rana, Meletios Doulgkeroglou, Stephen Kearns, Jack Kelly, Yves Bayon, Dimitrios I. Zeugolis Published in: Methods in Cell Biology, 2019 Publisher: Elsevier DOI: 10.1016/bs.mcb.2019.11.003 Production and Characterization of Chemically Cross-Linked Collagen Scaffolds Author(s): Ignacio Sallent, Héctor Capella-Monsonís, Dimitrios I. Zeugolis Published in: Collagen - Methods and Protocols, Issue 1944, 2019, Page(s) 23-38, ISBN 978-1-4939-9094-8 Publisher: Springer New York DOI: 10.1007/978-1-4939-9095-5_3 Conference proceedings (3) Concept Design of a New Portable Medical Device for Lymphedema Monitoring: A EIT Health ClinMed Summer School Project Author(s): Jordi Tisaire, Elena Rodrigo, Sofia Ribeiro, Mariachiara Ricci, Juan Cuellar, Dimitrios Zeugolis, Yves Bayon, Isabel Rocha Published in: Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies, 2019, Page(s) 611-620, ISBN 978-989-758-353-7 Publisher: SCITEPRESS - Science and Technology Publications DOI: 10.5220/0007696706110620 Design and Characterization of Synthetic Biodegradable Films for Soft Tissue Engineering Author(s): Ribeiro, S.; Fernandes, E.; Gomes, M.; Reis, R.; Bayon, Y. and Zeugolis, D. Published in: Doctoral Consortium - Volume 1: DCBIOSTEC, 2019, Page(s) 28-32 Publisher: DCBIOSTEC Empowering Translation of New Ideas - A EIT Health ClinMed Summer School Overview Author(s): Sofia Ribeiro, Mariachiara Ricci, Albert Von Der Lieth, Yves Bayon, Dimitrios Zeugolis, Sylvia Pelayo, Isabelle Marque, Lionel Pazart Published in: Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies, 2019, Page(s) 603-610, ISBN 978-989-758-353-7 Publisher: SCITEPRESS - Science and Technology Publications DOI: 10.5220/0007696606030610 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
