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Crosstalk of Metabolism and Inflammation

Pubblicazioni

The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis

Autori: Lindsay Kosack, Riem Gawish, Alexander Lercher, Bojan Vilagos, Anastasiya Hladik, Karin Lakovits, Anannya Bhattacharya, Christopher Schliehe, Ildiko Mesteri, Sylvia Knapp, Andreas Bergthaler
Pubblicato in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322
DOI: 10.1038/s41598-017-10637-y

The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease

Autori: Lindsay Kosack, Bettina Wingelhofer, Alexandra Popa, Anna Orlova, Benedikt Agerer, Bojan Vilagos, Peter Majek, Katja Parapatics, Alexander Lercher, Anna Ringler, Johanna Klughammer, Mark Smyth, Kseniya Khamina, Hatoon Baazim, Elvin D. de Araujo, David A. Rosa, Jisung Park, Gary Tin, Siawash Ahmar, Patrick T. Gunning, Christoph Bock, Hannah V. Siddle, Gregory M. Woods, Stefan Kubicek, Elizabeth P.
Pubblicato in: Cancer Cell, Issue 35/1, 2019, Page(s) 125-139.e9, ISSN 1535-6108
DOI: 10.1016/j.ccell.2018.11.018

CD8+ T cells induce cachexia during chronic viral infection

Autori: Hatoon Baazim, Martina Schweiger, Michael Moschinger, Haifeng Xu, Thomas Scherer, Alexandra Popa, Suchira Gallage, Adnan Ali, Kseniya Khamina, Lindsay Kosack, Bojan Vilagos, Mark Smyth, Alexander Lercher, Joachim Friske, Doron Merkler, Alan Aderem, Thomas H. Helbich, Mathias Heikenwälder, Philipp A. Lang, Rudolf Zechner, Andreas Bergthaler
Pubblicato in: Nature Immunology, Issue 20/6, 2019, Page(s) 701-710, ISSN 1529-2908
DOI: 10.1038/s41590-019-0397-y

Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function

Autori: Alexander Lercher, Anannya Bhattacharya, Alexandra M. Popa, Michael Caldera, Moritz F. Schlapansky, Hatoon Baazim, Benedikt Agerer, Bettina Gürtl, Lindsay Kosack, Peter Májek, Julia S. Brunner, Dijana Vitko, Theresa Pinter, Jakob-Wendelin Genger, Anna Orlova, Natalia Pikor, Daniela Reil, Maria Ozsvár-Kozma, Ulrich Kalinke, Burkhard Ludewig, Richard Moriggl, Keiryn L. Bennett, Jörg Menche, Paul
Pubblicato in: Immunity, Issue 51/6, 2019, Page(s) 1074-1087.e9, ISSN 1074-7613
DOI: 10.1016/j.immuni.2019.10.014