Nanobody-targeted photodynamic therapy to kill cancer

Informazioni relative al progetto

KILLCANCER

ID dell’accordo di sovvenzione: 677582

DOI 10.3030/677582

Progetto chiuso

Data della firma CE 27 Aprile 2016

Data di avvio 1 Luglio 2016

Data di completamento 31 Dicembre 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 500 000,00

Contributo UE € 1 500 000,00

Coordinato da

UNIVERSITEIT UTRECHT
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (12)

Dual Targeting of Endothelial and Cancer Cells Potentiates In Vitro Nanobody-Targeted Photodynamic Therapy

Autori: Vida Mashayekhi, Katerina T. Xenaki, Paul M.P. van Bergen en Henegouwen, Sabrina Oliveira
Pubblicato in: Cancers, Numero 12/10, 2020, Pagina/e 2732, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12102732

Nanobody-targeted photodynamic therapy for the treatment of feline oral carcinoma: a step towards translation to the veterinary clinic

Autori: Irati Beltrán Hernández, Guillaume C.M. Grinwis, Alessia Di Maggio, Paul M.P. van Bergen en Henegouwen, Wim E. Hennink, Erik Teske, Jan W. Hesselink, Sebastiaan A. van Nimwegen, Jan A. Mol and Sabrina Oliveira
Pubblicato in: Nanophotonics, 2021, ISSN 2192-8614
Editore: De Gruyter
DOI: 10.1515/nanoph-2021-0195

Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions

Autori: Demian van Straten, Vida Mashayekhi, Henriette de Bruijn, Sabrina Oliveira, Dominic Robinson
Pubblicato in: Cancers, Numero 9/12, 2017, Pagina/e 19, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers9020019

Nanobody-Targeted Photodynamic Therapy Selectively Kills Viral GPCR-Expressing Glioblastoma Cells

Autori: Timo W. M. De Groof, Vida Mashayekhi, Tian Shu Fan, Nick D. Bergkamp, Javier Sastre Toraño, Jeffrey R. van Senten, Raimond Heukers, Martine J. Smit, Sabrina Oliveira
Pubblicato in: Molecular Pharmaceutics, Numero 16/7, 2019, Pagina/e 3145-3156, ISSN 1543-8384
Editore: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.9b00360

VHH-Photosensitizer Conjugates for Targeted Photodynamic Therapy of Met-Overexpressing Tumor Cells

Autori: Raimond Heukers, Vida Mashayekhi, Mercedes Ramirez-Escudero, Hans de Haard, Theo Verrips, Paul. van Bergen en Henegouwen, Sabrina Oliveira
Pubblicato in: Antibodies, Numero 8/2, 2019, Pagina/e 26, ISSN 2073-4468
Editore: MDPI
DOI: 10.3390/antib8020026

Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

Autori: Else Driehuis, Sacha Spelier, Irati Beltrán Hernández, Remco de Bree, Stefan M. Willems, Hans Clevers, Sabrina Oliveira
Pubblicato in: Journal of Clinical Medicine, Numero 8/11, 2019, Pagina/e 1880, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm8111880

Preclinical and Clinical Evidence of Immune Responses Triggered in Oncologic Photodynamic Therapy: Clinical Recommendations

Autori: Beltrán Hernández, Yu, Ossendorp, Korbelik, Oliveira
Pubblicato in: Journal of Clinical Medicine, Numero 9/2, 2020, Pagina/e 333, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9020333

Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session

Autori: Marion M. Deken, Marta M. Kijanka, Irati Beltrán Hernández, Maxime D. Slooter, Henriette S. de Bruijn, Paul J. van Diest, Paul M.P. van Bergen en Henegouwen, Clemens W.G.M. Lowik, Dominic J. Robinson, Alexander L. Vahrmeijer, Sabrina Oliveira
Pubblicato in: Journal of Controlled Release, Numero 323, 2020, Pagina/e 269-281, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2020.04.030

Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging

Autori: Henriette S. de Bruijn, Vida Mashayekhi, Tom J.L. Schreurs, Pieter B.A.A. van Driel, Gustav J. Strijkers, Paul J. van Diest, Clemens W.G.M. Lowik, Ann L.B. Seynhaeve, Timo L.M. ten Hagen, Jeanine J. Prompers, Paul M.P. van Bergen en Henegouwen, Dominic J. Robinson, Sabrina Oliveira
Pubblicato in: Theranostics, Numero 10/5, 2020, Pagina/e 2436-2452, ISSN 1838-7640
Editore: Ivyspring International Publisher
DOI: 10.7150/thno.37949

The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses

Autori: Irati Beltrán Hernández, Mathieu L. Angelier, Tommaso Del Buono D’Ondes, Alessia Di Maggio, Yingxin Yu, Sabrina Oliveira
Pubblicato in: Cancers, Numero 12/4, 2020, Pagina/e 978, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040978

Vascular targeted photodynamic therapy: A review of the efforts towards molecular targeting of tumor vasculature

Autori: Vida Mashayekhi, Charlotte Op 't Hoog, Sabrina Oliveira
Pubblicato in: Journal of Porphyrins and Phthalocyanines, Numero 23/11n12, 2019, Pagina/e 1229-1240, ISSN 1088-4246
Editore: Society of Porphyrins and Phthalocyanines
DOI: 10.1142/s1088424619300180

Molecular targets for anticancer therapies in companion animals and humans: what can we learn from each other?

Autori: Irati Beltrán Hernández, Jannes Z. Kromhout, Erik Teske, Wim E. Hennink, Sebastiaan A. van Nimwegen, Sabrina Oliveira
Pubblicato in: Theranostics, 2021, ISSN 1838-7640
Editore: Ivyspring International Publisher
DOI: 10.7150/thno.55760